Posted by polarbear206 on March 25, 2002, at 16:31:01
In reply to Re: Usually not, posted by OldSchool on March 22, 2002, at 16:13:34
> > I'm trying to build up to a therapeutic imipramine dose but at 60 I'm already tired. As I need to go to 200, this is discouraging. My doc says if I soldier through--over months--it will eventually subside. Anyone have experience that speaks to this? I already failed on nortriptyline which made me totally lightheaded and woozy.
> >
> > Thanks!
> > Lia
>
>
> Lia, usually TCAs are quite sedating. Tofranil is one of the most sedating antidepressants there is. Its from the anti-cholinergic side effects, thats a big part of it. I took Pamelor once for a few months and the sedation never went away. TCAs are just generally very sedating drugs, with the one exception of desipramine which some people like and claim is somewhat stimulating.
>
> If it were me, Id be opting for a modern class antidepressant. The modern class ADs generally have a much more tolerable side effect profile.
>
> Old School
Lia,
Elavil is the most sedating among the tricyclics. I also take imipramine. The sedation will wear off once you get used to the med and your body adjusts. This class of meds works the best for those with more severe "endogenous" depressions. It is very activating because it targets more then one neurotransmitter. The ssri's taken alone blunted my emotions. I feel more like my old self with the tricyclics. Good Luck.
poster:polarbear206
thread:99482
URL: http://www.dr-bob.org/babble/20020322/msgs/100082.html