Posted by Tony P on September 5, 2001, at 1:32:59
In reply to Re: Wellbutrin - weight loss or appetite gain? » Tony P, posted by SalArmy4me on September 4, 2001, at 16:01:09
Thanks for sharing. I was starting to feel that unnoticed, poor me, feeling when nobody responded right away! Perhaps my experience is uncommon, but bupropion has been so energizing for me that having a huge appetite just seems a natural part of it, so I'm surprised if more people don't experience that. Of course you're right Sal - even if I'm eating more food I might be processing it differently with the effects of the bupropion. I will put it on my list for when I see my MD day after tomorrow.
It occurs to me that if I were responding to someone _else's_ post, I would be inclined to say to them somrthing like, "Trust your body and listen to it, appreciating the pleasure of increased appetite but recognizing when you're full too. And if you build in enough of the other healthy activities, like exercise, leisure of a restorative sort, better sleep habits - you know your own list - your body will mostly look after itself. Don't waste mental energy trying to predict the future! Time will tell, and 10 or 15 lbs on the scale one way or the other is only a number after all - how your body feels and functions is what counts."
Well, that's my self-affirmation for the night; thanks for giving me a chance to say it out loud as it were!
Tony
> What about the possibility that you will lose weight due to a change in your metabolism on Wellbutrin, regardless of appetite?
>
> Diabetes
> Volume 50 SUPPLEMENT 2 June 2001 p A21
> Buproprion SR Significantly Enhances Weight Loss When Used with a Moderate-Intensity Lifestyle Intervention:
>
> "Preliminary studies suggest that Bupropion SR, approved for depression and smoking cessation, is an effective adjunct to diet for weight loss. We conducted a 6-month multi-center, randomized, double-blind, placebo-controlled, parallel-group study to test the safety and efficacy of Bupropion SR as an adjunct to a balanced energy-restricted diet and lifestyle program to treat obese adults. We enrolled 327 women and men, aged 18-65 years, with BMIs of 30-43. We excluded subjects who had a history of seizures, anorexia, bulimia, depression, psychosis, cigarette or substance abuse. After a 2-week run-in period subjects were randomly allocated to placebo, 300 mg/day, or 400 mg/day Bupropion SR. The lifestyle intervention included an energy-restricted diet (600 kcal deficit), use of 2 meal replacements/day, recording miles walked (pedometer), and a lifestyle diary. Subjects received dietetic counseling every 2-4 weeks. Retention rate at 24-weeks was ~70% and was similar in all groups. The weight loss (% of initial weight) and loss of >5% at 6 months (intention to treat analysis) are summarized in table."
poster:Tony P
thread:77387
URL: http://www.dr-bob.org/babble/20010902/msgs/77781.html