Posted by paxvox on August 16, 2001, at 20:21:39
In reply to Re: Does wellbutrin sr work for anxiety? » paxvox, posted by Janelle on August 16, 2001, at 18:01:39
> Thanks for the clarification. I could have sworn that Wellbutrin IS a dopamine agonist and does bbind to dopamine receptors, but I apparently am mistaken.
>
> I guess I thought this because it must block dopamine re-uptake, since it allows more free-floating dopamine to remain in the sytem.According to PDR 2000 " Wellbutrin is a weak blocker of the neuronal uptake of serotonin and norepinephrine, it also inhibits the neuronal reuptake of dopamine to some extent...it causes dose-related CNS stimulant effects."
So, while not an agonist of dopamine, it does allow some of it to "free-float".
However, SalArmy4me had a link to the guy that helped develop Wellbutrin originally in the late 1970's that expounds on these issues, and on the efficacy of bupropion.
poster:paxvox
thread:75255
URL: http://www.dr-bob.org/babble/20010814/msgs/75336.html