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Re: Wellbutrin. Sustained Release vs Imediate

Posted by SLS on June 5, 2001, at 8:11:44

In reply to Re: Wellbutrin. Sustained Release vs Imediate » Stephania, posted by Sunnely on June 4, 2001, at 23:43:34

Hi.


> > What is the difference of the SR vs the imediate release? Are there different sides? How does a pdoc chose which is a good choice?

> The main difference, IMHO, between Wellbutrin SR (sustained release) and Wellbutrin IR (immediate release) is in the degree of their peaks in blood concentrations. In contrast to the IR, the SR formulation avoids the rapid and high peaks in blood concentrations therefore, decreasing the risk of seizures.

I know someone who describes that the SR version actually feels different and better than the IR. It is almost as if they are different drugs. I have also seen the same sort of thing described about the patch version of selegiline feeling different and superior to the oral preparation. The differences described are global, and not limited to diurnal spiking or ebb and flow of effect. I wonder if the same thing is observed with the two preparations of Effexor.


- Scott

 

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