Posted by SalArmy4me on May 3, 2001, at 14:31:01
In reply to Re: -Tranxene- The lost benzodiazepine-Discussion, posted by Mr.Scott on May 3, 2001, at 9:41:06
Here's my "take" on Neurontin:
--It has anti-anxiety and antidepressant actions.
--It has no anticholinergic side-effects.
--Few sexual side-effects.
--It now comes in 600 and 800 mg tablets, reducing the number of pills one takes per day
--It requires no blood-levels taken.
--It has gained the respect of psychiatrists world-wide in less than a decade.
--Gabapentin has few negative drug interactions; it can even be taken with MAOIs and moclobemide.Here are the studies that prove Neurontin's efficacy:
1: Jefferson JW.
Benzodiazepines and anticonvulsants for social
phobia (social anxiety disorder).
J Clin Psychiatry. 2001;62 Suppl 1:50-3.
PMID: 112060352: Janowsky DS.
New Treatments of Bipolar Disorder.
Curr Psychiatry Rep. 1999 Dec;1(2):111-113.
PMID: 111229123: Keck PE, Mendlwicz J, Calabrese JR, Fawcett J,
Suppes T, Vestergaard PA, Carbonell C.
A review of randomized, controlled clinical
trials in acute mania.
J Affect Disord. 2000 Sep;59 Suppl 1:S31-S37.
PMID: 111218254: [No authors listed]
Valproate and other anticonvulsants for psychiatric disorders.
Med Lett Drugs Ther. 2000 Dec 11;42(1094):114-5.
PMID: 111148425: Vieta E, Martinez-Aran A, Nieto E, Colom F,
Reinares M, Benabarre A, Gasto C.
Adjunctive gabapentin treatment of bipolar disorder.
Eur Psychiatry. 2000 Nov;15(7):433-7.
PMID: 111129366: Frye MA, Ketter TA, Kimbrell TA, Dunn RT, Speer AM,
Osuch EA, Luckenbaugh DA, Cora-Ocatelli G, Leverich GS, Post RM.
A placebo-controlled study of lamotrigine and
gabapentin monotherapy in refractory mood disorders
J Clin Psychopharmacol. 2000 Dec;20(6):607-14.
PMID: 11106131
8: McElroy SL, Keck PE.
Pharmacologic agents for the treatment of acute
bipolar mania
Biol Psychiatry. 2000 Sep 15;48(6):539-57.
[Record as supplied by publisher]
PMID: 110182269: Bennett J, Goldman WT, Suppes T.
Gabapentin for treatment of bipolar and schizo-
affective disorders.
J Clin Psychopharmacol. 1997 Apr;17(2):141-2.
PMID: 1095049410: Pande AC, Pollack MH, Crockatt J, Greiner M,
Chouinard G, Lydiard RB, Taylor CB, Dager SR, Shiovitz T.
Placebo-controlled study of gabapentin treatment
of panic disorder.
J Clin Psychopharmacol. 2000 Aug;20(4):467-71.
PMID: 1091740812: Ghaemi SN, Gaughan S.
Novel anticonvulsants: a new generation of mood stabilizers?
Harv Rev Psychiatry. 2000 May-Jun;8(1):1-7. Review.
PMID: 1082429215: Brannon N, Labbate L, Huber M.
Gabapentin treatment for posttraumatic stress disorder.
Can J Psychiatry. 2000 Feb;45(1):84.
PMID: 1069649516: Dallocchio C, Buffa C, Mazzarello P.
Combination of donepezil and gabapentin for behavioral
disorders in Alzheimer's disease.
J Clin Psychiatry. 2000 Jan;61(1):64.
PMID: 1069565217: Herrmann N, Lanctot K, Myszak M.
Effectiveness of gabapentin for the treatment of
behavioral disorders in dementia.
J Clin Psychopharmacol. 2000 Feb;20(1):90-3.
PMID: 1065321419: Schaffer CB, Schaffer LC.
Open maintenance treatment of bipolar disorder spectrum
patients who responded to gabapentin augmentation in
the acute phase of treatment.
J Affect Disord. 1999 Oct;55(2-3):237-40.
PMID: 1062889420: Maurer I, Volz HP, Sauer H.
Gabapentin leads to remission of somatoform pain
disorder with major depression.
Pharmacopsychiatry. 1999 Nov;32(6):255-7.
PMID: 1059993621: Sokolski KN, Green C, Maris DE, DeMet EM.
Gabapentin as an adjunct to standard mood stabilizers
in outpatients with mixed bipolar symptomatology.
Ann Clin Psychiatry. 1999 Dec;11(4):217-22.
PMID: 1059673622: Brown ES, Hong SC.
Antidepressant-induced bruxism successfully treated
with gabapentin.
J Am Dent Assoc. 1999 Oct;130(10):1467-9.
PMID: 1057059023: Botts SR, Raskind J.
Gabapentin and lamotrigine in bipolar disorder.
Am J Health Syst Pharm. 1999 Oct 1;56(19):1939-44. Review.
PMID: 1055491124: Magnus L.
Nonepileptic uses of gabapentin.
Epilepsia. 1999;40 Suppl 6:S66-72; discussion S73-4. Review.
PMID: 1053068625: Connor KM, Davidson JR, Sutherland S, Weisler R.
Social phobia: issues in assessment and management.
Epilepsia. 1999;40 Suppl 6:S60-5; discussion S73-4. Review.
PMID: 10530685
poster:SalArmy4me
thread:61421
URL: http://www.dr-bob.org/babble/20010424/msgs/61529.html