Posted by vince on April 8, 2001, at 1:20:35
I've been taking Neurontin for about 2 1/2 months now. It has helped some. It mainly helps me with what I call psychological pain. (I think this pain may be what is technically labeled as dysphoria). But Neurontin doesn't help with all my symptoms of depression. So about three weeks ago my doc added in a combination of Prozac and nortriptyline because ssri/tca is one combination that I haven't tried. So now I’m taking Neurontin, Prozac and nortriptyline. I've found that the nortriptyline causes me to feel very sleepy and extremely lazy the next day. I just flop down anywhere and snooze. Even when I do wake up, I feel too tired to do anything. I don't remember being this tired on tca's in the past, but it’s been a long, long time since I've used them. Maybe when I was younger this symptom wasn’t so noticeable. I would like to give this combination a fair trial but I can’t tolerate this much somnolence.
Question: I have some adrafinil that I bought a couple of months ago but haven't tried yet. I'm hoping that it might remedy the somnolence caused by the nortriptyline. Does anyone have any idea as to whether there might be an adverse reaction between adrafinil and the ssri/tca mix? Would there be any undesirable overlap in brain chemistry between say the nortriptyline and the adrafinil, e.g. norepinephrine?
Another option might be switching the tca to desipramine, Is desipramine as sedating as nortiptyline?
Vince
poster:vince
thread:59079
URL: http://www.dr-bob.org/babble/20010403/msgs/59079.html