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Re: Melatonin + Depakene + Risperdal - OK ?!

Posted by Ted on April 4, 2001, at 12:31:40

In reply to Melatonin + Depakene + Risperdal - OK ?!, posted by jimmygold70 on April 4, 2001, at 9:16:25

Jimmy,

I don't recommend it. Valproic Acid (Depakote & Depakene) is a nasty drug with lots of side effects, so be especially careful. Talk to your doctor and see if something else would work, like

- raising your depakene dose
- take klonopin
- take ambien

Ted

> I'm taking Risperdal 1mg/day + Depakene 400mg/day. Since Depakene dose is still too low to contrast my hyperarousal, I'm taking melatonin for sleep. Actually, I can't fall asleep without 3-6mg melatonin. I've never discussed it with my physician, but is that combination OK ? Can melatonin interact with any of these ?
> (After all, melatonin is a 5-HT metabolite, and risperdal is a 5-HT2 antagonist: I'm afraid of either augmentation or loss of effect...)
>
> Jimmy


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