Posted by JohnX on March 16, 2001, at 0:33:05
Just thought I'd drum up some quick thoughts
or links on TD causes.My primary understanding of what causes TD particularly in the older neuroleptics (anti-psychotics), is that chronic D2 antagonism in the nigrostriatal pathway will cause spawning of new D2 receptors to couteract this. Sometimes when the neuroleptic is removed, the body is unable to "undue" the D2 receptors it has spawned, and this can cause the hyperkinetic movement disorders in TD.
Are there other know hypothesis/causes for TD?
-John
poster:JohnX
thread:56627
URL: http://www.dr-bob.org/babble/20010310/msgs/56627.html