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Re: Ziprasidone: More on tardive dyskinesia ..

Posted by ShelliR on March 9, 2001, at 21:30:32

In reply to Re: Ziprasidone: Not so fast., posted by Sunnely on March 9, 2001, at 16:32:30

Three questions re ziprasidone:

(1) Is the risk of td the same as for the other atypical antipsychotics? Any information out about that?

(2) I have read a lot about the things that make the risk of td greater (e.g, age, duration of taking medication, etc.). Everything I read says, "the risk is much smaller with atypical antipsychotics" or the risk is "very small".
I can't find any real statistics. Even in a release about resperidal (sp?), the results presented were again a comparison against older antipsychotics, AND said "significantly lower" AND the study was only three months long. So in three months some people obviously developed TD. I am keeping in mind that the subjects of this study were schizophrenic and I believe took at least 10mg. But still, this is just a three month period. So what does a smaller percentage actually mean? One percent, five percent? Or is this not known exactly because no one really wants to do a study to find out.

(3) I have tried all the other atypical antipsychotics (except zyprexa because of fear of weight gain) and have not been able to tolerate any of them. Has anyone else not been able to tolerate one because of side effects yet tolerate another--sort of like ads in general.

I am not trying to be an alarmist. I am just trying to make an educated decision on whether to try ziprsidone. And I feel frustrated at the constant reference to "smaller risk" because I don't know how to evaluate that.

Thanks for any replies. Shelli


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poster:ShelliR thread:54700
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