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Re: MAOIs are safe for you: consider them now

Posted by blackjack on March 2, 2001, at 16:29:59

In reply to MAOIs are safe for you: consider them now, posted by SalArmy4me on March 2, 2001, at 9:18:06

I had 2 hypertensive crises while taking Parnate, and in neither case had I had any food that should have been high enough in tyramine to trigger it. The problem with Parnate is that it metabolizes into, among other things, an amphetamine-like chemical that can trigger spontanious hypertensive crises. It's really rare tho. The worse of the two crises was like being beaten in the back of the head of the head with a 2x4. The other one was just a bad headache.

But, annoying as these episodes were, the only real danger MAOI's present is, like Sal said, when they are mixed with other drugs. Which can be annoying if you get a cold or have asthma...

All that being said, Parnate was far and away the most effective AD I ever took, and if it hadn't started working (I seem to have built an actual tolerence--it took increasing dosages to keep from having withdrawl symptoms) I'd be taking it today, cheese or no cheese.


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