Posted by PhoenixGirl on January 24, 2001, at 14:41:28
Drugs that increase the effect of serotonin apparently decrease dopamine. If these drugs are taken for years, can dopamine depletion continue even after they are stopped?
I've heard that drugs that increase dopamine, like amphetamines, will in the long term deplete dopamine (or something like that). Do scientists even know about long-term dopamine depletion from serotonergic and dopaminergic drugs?
The reason I'm asking is that I used to have a decent libido when I was on imipramine for a few years, but lost it during subsequent drugs like anafranil and celexa. I was on imipramine for about 3 years, and on the more serotonergic drugs for about 5 years. In the past two months, I've been on desipramine, which is similar to imipramine and actually less likely to cause sexual side effects than imipramine, but my libido has only slightly improved
and is not as good as it was on imipramine. I am wondering whether the especially libido-ruining drugs
have caused long-term libido problems in my brain.
poster:PhoenixGirl
thread:52430
URL: http://www.dr-bob.org/babble/20010122/msgs/52430.html