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Re: Scott, no liver? - It gives me gas. » allisonm

Posted by SLS on October 25, 2000, at 16:00:58

In reply to Scott, no liver?, posted by allisonm on October 21, 2000, at 21:00:09

NO LIVER !

:-)

renal = kidney
metabolized = liver
hepatic = liver


"Elimination: Gabapentin is eliminated from the systemic circulation by renal excretion as unchanged drug. Gabapentin is not appreciably metabolized in humans."

http://www.rxlist.com/cgi/generic/gabapent_cp.htm


"Gabapentin is not appreciably metabolized in humans, is eliminated solely by renal excretion, and can be removed from plasma by hemodialysis.

Gabapentin does not induce or inhibit hepatic mixed function oxidase enzymes responsible for drug metabolism, does not interfere with the metabolism of commonly coadministered antiepileptic drugs, and is minimally bound to plasma proteins."

http://www.rxmed.com/monographs/neurntin.html

 

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