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Re: Polypharmacy

Posted by LucindaLinda on September 2, 2000, at 2:22:04

In reply to Re: Polypharmacy, posted by ash on August 31, 2000, at 10:26:57

> I'd like to add one more thing about the sedating A/D's (Serzone, Remeron, Trazadone) and A/P's (Olanzapine). Serzone supposedly will help normalize one's sleep architecture, and I tried it for quite a while since my lab sleep studies have shown that I get zero Slow Wave Sleep (SWS, Stages 3 and 4 NREM). In a recent paper, Olanzapine was shown to increase SWS by 50 to 75% in healthy volunteers after just one night of dosing in the 5-10 mg range. Cindy, as you may be aware, lack of restful SWS is strongly implicated in the etiology of fibromylagia(FMS) and myofascial pain syndromes. So you might consider playing around with the dosages of Serzone and/or Olanzapine if you have FMS.

I have FMS and tried Serzone along with doxepin and flexeril and began to wake up gasping for air and realized (after dreaming about it) that I had stopped breathing in my sleep. I discontinued the Serzone immediately and after doing some research found that Serzone repressing breathing in some people when combined with other drugs.
Would be interested in more information about getting my sleep patterns back to normal? so that I can get off the sleep meds.


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poster:LucindaLinda thread:44126
URL: http://www.dr-bob.org/babble/20000822/msgs/44277.html