Posted by Greg on June 12, 2000, at 9:46:38
In reply to Re: Cam - A question for a friend? » Greg, posted by Cam W. on June 12, 2000, at 9:25:01
Cam,
Thanks for the quick response.
She has been taking the Zoloft for about 3 weeks this time, I'm unsure about the dose, but will see her tonight and get back to you with it. I think her main concern is that she didn't have the fatigue effect the first time and doesn't understand why it is happening now. She said she responded to it very quickly the first time out.
She also told me that while she is experiencing the fatigue, she wakes up 4-5 times during the night like someone turning on a light switch. Is this common? I thought about suggesting Wellbutrin, but if she is having some insomnia, it might not be the right thing for her? Decided to keep my mouth shut and leave it up to the experts like yourself.
I was changed from WB (because of the irrating effect I was experiencing) to Prozac a while ago. The Prozac worked OK for a while and then the fatigue started coming back. So I was put on a combo of the two (which I am told is pretty common), and things seem to be stabilizing well. My thanks for all your input on the subject!
Thanks,
Greg
> Greg - A couple of questions about your friend. How long has she been taking the Zoloft this time? What dose is she taking? (ie could these be 'start-up' side effects?) How long did it take her to respond to Zoloft the 1st time?
>
> The tired feeling could also be an effect of the depression and the Zoloft hasn't kicked in, yet. Has it been the 8 weeks taking Zoloft this time?
>
> Tell her not to give up too soon. The next step, if she needs to take it (if necessary) is to probably try another SSRI (since responded to one before). Maybe Paxil, especially if there is an anxiety component to this depression, due to it's reactive nature (ie a depression caused by an acute stressor).
>
> As to differences antidepressant response between males and females, I kinda glanced at a recent article before I left on vacation about this. It would be available on-line from one of the nice Journals (eg Archives of General Psychiatry, other Archives, British Medical Journal, British Journal of Psychiatry, JAMA, American Family Physician, or perhaps a paper published on Medscape - I can't recall). This paper is at work and I won't be going in for a week or two, just yet. I think (but am not certain) that the conclusion of the study said that there are no "clinical" differences in response to antidepressants between the sexes, at least none we can utilize, yet.
>
> Hope this helps - Cam W.
poster:Greg
thread:37011
URL: http://www.dr-bob.org/babble/20000610/msgs/37019.html