Posted by michael on June 11, 2000, at 16:57:07
In reply to Re: question about dopamine, posted by JohnL on June 10, 2000, at 19:19:44
Maybe I'm misunderstandin the question - was it essentially looking for dopamine agonists?
There are all the items that andrewB is exploring: amisulpride (low dose), mirapex?, selegiline (low dose - maoi-b), even sinemet (levodopa). Or maybe I'm addressing a different question than the one that was actually asked?
> CarolAnn,
>
> SJW affects dopamine. Though all its mechanisms are not fully understood, they have shown that it inhibits the reuptake of serotonin, NE, and dopamine in about equal proportions. As for SAMe, again I don't think they know enough about it. But I have seen in literature that it too has dopamine enhancing effects.
>
> But if you're looking for something that affects purely dopamine and nothing else, I can't think of anything. Some people claim taking the amino acid tyrosine directly boosts dopamine. I think it can to a certain extent, but there is a built in feedback loop that prevents this from working as much as we would like. I have yet to actually see anyone here actually get well with tyrosine supplementation, but it's touted a lot at the websites that sell it. Who knows.
>
> I know this isn't what you we referring to. I'm just throwing this in for a bit of light trivia. Marijuana boosts dopamine 6-fold. And when you drink alcohol, it causes a rush of dopamine. But as we all know, these are very short-lived effects. Definitely not what we're looking for. :-)
> JohnL
poster:michael
thread:36828
URL: http://www.dr-bob.org/babble/20000610/msgs/36946.html