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Re: Question for JohnL/(RE:remeron/anafranil)

Posted by JohnL on April 14, 2000, at 15:45:16

In reply to Re: Question for JohnL/(RE:remeron/anafranil), posted by Scott L. Schofield on April 14, 2000, at 12:50:04


> Is there any need to be wary of serotonin syndrome?
>
>
> - Scott

Good point Scott. I think anytime two serotonin medications are combined there should be an awareness of serotonin overload risk. Low starting doses and gradual increases is the best way I know of to keep the risks in check. Diarrhea accompanied with either unusual euphoria or unusual malaise is an early warning sign...a warning sign to back off. I think the risk is low, but nevertheless a risk worth monitoring. In my experience there is a lot of wisdom when people tell me "go low and slow". There have been times I think I got too aggressive too fast with dosing cocktails and I think I've experienced the outer edges of serotonin syndrome a couple of times. It would not have happened had I been a little more patient and conservative. I heard a saying once that I think has a lot of wisdom..."there are no safe drugs...only safe doses".


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