Re: med augmentation

Posted by Cam W. on January 25, 2000, at 7:15:40

In reply to med augmentation, posted by mtl on January 25, 2000, at 1:06:22

> Just wondering if selegiline can be used with venlafaxine?
>
> Looking to augment for anorgasmia, and chronic low energy. I'm currently taking 150mg venlafaxine/day. Already tried wellbutrin - no help for either issue.
>
> How about stimulants with venlafaxine? Dexidrine or ritilan? Would that be likly to help both issues, or just the low energy?
>
> Or has anybody tried pindolol with venlafaxine?
>
> Thanks,
>
> mtl
MTL - Sorry to here about your antidepressant-induced problem. Anorgasmia is more common than reported, in the literature. Wellbutrin is the first thing to try, but, for you, is not useful.
I am not sure of anything that will work 100%, but
have seen a study where it is said that Viagra may work (am skeptical). As for pindolol, it blocks the shut-off mechanism for the release of serotonin, so it will increase levels of serotonin in the synaptic gap. Serotonin may be what is causing your anorgasmia and quite possible, lack of energy. Pindolol is usually used to make SSRIs work faster.
As for selegiline, a drug normally used in Parkinsonism, it is an MOA-B inhibitor.I have seen no studies for anorgasmia or fatigue with this drug. It is thought to increase dopamine in Parkinsonism patients, but what it would do for anorgasmia, I really don't know. It is an awfully potent drug and would only use it as a last resort.
How long have you been taking Venlafaxine? Many times the sexual side effects caused by antidepressants will abate after about 6 months. Maybe try giving your body a little more time to adjust.
Also, stimulants like dexedrine may help, but the addictive potential would make me consider using them only with great caution. They can also interupt sleep patterns. I have seen no studies using dexedrine for anorgasmia, but have seen it augment the antidepressant activity of SSRIs.
Search the literature. Try PubMed or GratefulMed and do a search for anorgasmia. See what the experts have said. PubMed is at

Thread

med augmentation mtl 1/25/00
Re: med augmentation Cam W. 1/25/00
Cam W: med augmentation for Serzone? Mrs. G 1/25/00
Re: med augmentation Renee N 1/25/00
Re: Cam W: med augmentation for Serzone? Cam W. 1/25/00
Re: Cam W: med augmentation for Serzone? Cam W. 1/26/00
Re: Cam W: med augmentation for Serzone? Mrs. G 1/26/00

Post a new follow-up

Notify the administrators

Start a new thread

poster:Cam W. thread:19639
URL: http://www.dr-bob.org/babble/20000112/msgs/19647.html