Posted by JohnB on November 11, 1999, at 8:53:55
In reply to Neurontin Social Phobia Hype?, posted by Rick on November 11, 1999, at 0:13:51
Rick, yes, I think you are missing the point. The study was conducted with dosages ranging from 1800 mg/day to 3600 mg/day. So, the overall efficacy ratings are an average of patient response at the different dosages. 1800 mg/day is supposed to be sub-therapeutic, as is 2400 mg/day, as far as social phobia is concerned. 3600mg/day to 4800 mg/day are where the results are suppose to kick in. Discounting the patients at dosages under 3600 mg/day, you can easily estimate that the response for the few at the higher dosages was SIGNIFICANTLY higher than a 30% response rate.
Parke-Davis is planning a follow-up study at the higher dosages, as indicated at the end of their study report.
JohnB
poster:JohnB
thread:14991
URL: http://www.dr-bob.org/babble/19991108/msgs/15002.html