Posted by Jim on April 12, 1999, at 19:02:34
In reply to Re: Refractory depression--naltrexone theories?, posted by Wayne R. on April 12, 1999, at 8:00:51
Wayne,
On your questions about who naltrexone
works for and why, I too am just an
interested (perhaps too interested!)
patient. I agree that most reports
(especially Lee Dante's) see it working
only as an augmentation strategy with
things like SSRIs (and also sometimes
tricyclics). But when I did some of my own
research on naltrexone use across
the board, I did find a bunch of places
in the alcholism & autism literature where
there was some question about whether it
might have an antidepressant effect in its
own right. This has not really been
formally researched so you're right to see
naltrexone as remaining basically an
augmentation strategy for the time being.
(My *theory* that I posted was basically
the best one that I as a non-specialist could
come up with!) If there are other people
that naltrexone has helped, I'd be interested
to see them come out of the woodwork too!
-Jim
poster:Jim
thread:4588
URL: http://www.dr-bob.org/babble/19990501/msgs/4770.html