Posted by Elizabeth on April 12, 1999, at 5:16:51
In reply to Re: New Medications for Social Phobia, posted by Terry on April 6, 1999, at 10:49:57
Well, first of all I didn't say they should be first-line treatment; I said I think it is worthwhile to try SSRIs and high-potency benzodiazepines first. (In regards to the use of benzodiazepines, see Davidson et al "Treatment of SP with Clonazepam and Placebo" (1993), for example.)
A lot of people have this attitude, which is unfortunate. It turns out that a lot of the supposed interactions don't actually occur experimentally. Many of the food items listed as "restricted" on various MAOI diets are there as a result of isolated and poorly-documented case reports. Shulman and colleagues (1989, 1996, 1997, 1999) have done some long-overdue research in this area and made recommendations for a simplified diet based on actual tyramine (and dopa) levels in foods and on well-documented case reports. (A medline search for "Shulman KI" should give you the abstracts.)
By the way, I've taken MAOIs (following Shulman's dietary recommendations). The only thing I found annoying to have to avoid was Sudafed.
poster:Elizabeth
thread:4113
URL: http://www.dr-bob.org/babble/19990401/msgs/4733.html