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Dr. Bob is Robert Hsiung, MD,
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Posted by elanor roosevelt on January 27, 2008, at 8:21:28
In reply to Re: Trivastal non-sustained release form, posted by clipper40 on January 27, 2008, at 7:13:34
I had no adverse reactions to starting at 50mg a day as long as i took it at night with food
might have had some tired mornings but not now
dreams are better immediately
Posted by clipper40 on January 27, 2008, at 11:29:15
In reply to Re: Trivastal non-sustained release form, posted by elanor roosevelt on January 27, 2008, at 8:21:28
Good to know! Thanks.
Posted by atmlady on January 27, 2008, at 11:30:55
In reply to Re: Trivastal and Ixel - Questions and Comments » atmlady, posted by bleauberry on January 26, 2008, at 19:24:58
Hi, Bleauberry! I too have the runny nose with ixel! Funny, huh? That's too bad you couldn't continue with it; I know how you feel - I have the same relationship with Lexapro.
I was frightened to take the Trivastal, too. I took my first dose at night because I was afraid of the nausea and sleepiness that some others had reported. I had taken my 450mg of wellbutrin that morning, so I was also afraid of what the the interaction might be between the two drugs. I took the dose with a slice of bread and some cheese and a glass of water about 9:30pm. Laid in the bed reading, trying to relax, but hyper-alert to any twitch, itch, pain, or ghostly movement out of the corner of my eye. Was afraid I'd get super sleepy really fast, kept waiting to feel sleepy but never did. Kept waiting to feel nausea but never did. Kept waiting to feel confused, irritable, crazy, weepy - whatever, but I never did. Still, I was afraid. Told my 14 year old daughter to sleep with me that night - thinking if I had a seizure or started sleepwalking or something strange, she would at least be around to help call 911. So yeah, I was totally anxious and paranoid about taking the mystery pills. I stayed up for many hours, just thinking about stuff and things, quite alert, but finally calming down, eventually fell asleep about 3. Up at 5:30 feeling fine.
In the morning I thought, man, this stuff must be sugar pills - it must not be working because I don't feel any different. But I kept plugging at it - I was running out of wellbutrin and did not want to buy more, but the ixel had not yet arrived. So I decided to wean off the wellbutrin and replace it with trivastal and if my mystery pills were genuine, not sugar pills, then I should be able to switch over with few problems - that was my hypothesis. And it worked. That day I took 300mg of wb, the next 150mg and the next zero. And increased the trivastal from 50, to 100 to 150 per day. And no withdrawal symptoms. So that's what told me that the trivastal does indeed work on dopamine. If it was a sugar pill I'd have been sick from dropping the wellbutrin so abruptly. During that first week of Trivastal, I took at least one nap a day, and I mean really great naps. I never slept well on wellbutrin, and felt like I was making up a lot of lost sleep. I started dreaming again, good dreams. In one dream I heard my mother (dead 10 years) talking to me as if she were right there. In another my boyfriend made love to me and it seemed real! So, good dreams. Which I think might be because my unconscious and well as my conscious is beginning to experience pleasure and joy. Mind you, it's not like I'm bounding around in a joyful mania. In fact, the amount of pleasure and joy I'm experiencing on trivastal is probably still less than a normal person feels, but it's more than I've felt in a while. And really, for an anxious person like me who (really, I swear) does not like to take pills, it's just perfect. I prefer mild over wild, because I feel a little more in control.
Also, I kinda feel like it's working better as time goes by. Like maybe the blood levels had to be at a certain level for a certain period before it really began it's good works. Maybe my dopamine receptors needed to learn what to do with the new chemicals floating around. Then again, it may be the addition of ixel that seems to make it feel like it's working better.
Anyway, Bleauberry, I wouldn't be too afraid of taking that first dose. If you are paranoid like me about how it might affect you, take it in the morning on your day off, so you can putter around
and won't lay in bed worrying about whether your heart is still beating correctly, like I did! It does not make me sleepy at all. But if it makes yo sleepy you can always take a nap if it's your day off.Hope this helps you take the leap!
ATMlady
Posted by atmlady on January 27, 2008, at 11:48:46
In reply to Re: Trivastal non-sustained release form, posted by clipper40 on January 27, 2008, at 7:06:57
Hi, Clipper - No I'm using the LA, which I think means "long-acting", though for me, I think it lasts about 7-8 hours at the most. So I take it at 6am, noon and 6pm to try to keep a steady level. The 50mg pills I received are coated round tablets. I can't imagine they would be easy to cut in half without making a mess, but I'm sure it could be done. Might cause more of a problem with nausea if you take half a caplet and are missing that coating where it was cut, if you know what I mean.
I swear I remember reading in the package insert for the LA, of course right at the moment I can't find it, but I thought I read that it had two peaks - first one at 1 hour after ingesting and another smaller peak after 7 hours. I guess that's why they call it long-acting? But I can't say that I notice the second peak at all. Which is why I take them 6 hours apart. Then again, I was on the max dose of wellbutrin for quite a while and am used to continuous dopamine help. Someone who is relying on his own dopamine may notice the two peaks, but I don't.
Posted by Sigismund on January 27, 2008, at 18:58:32
In reply to Re: Trivastal non-sustained release form » clipper40, posted by atmlady on January 27, 2008, at 11:48:46
Any ideas about the duration of action of LA vs Retard?
Posted by clipper40 on January 27, 2008, at 21:09:04
In reply to Re: Trivastal non-sustained release form » clipper40, posted by atmlady on January 27, 2008, at 11:48:46
Guess I'd just have to be brave and take the whole pill then. Thanks.
Posted by Phillipa on January 27, 2008, at 23:50:39
In reply to Re: Trivastal non-sustained release form » atmlady, posted by clipper40 on January 27, 2008, at 21:09:04
Let us know how it goes sounds good so far for everyone. Phillipa
Posted by bulldog2 on January 28, 2008, at 14:47:40
In reply to Re: Trivastal LA vs Retard, posted by Sigismund on January 27, 2008, at 18:58:32
> Any ideas about the duration of action of LA vs Retard?
The retard is supposed to have a half life of 24 hours. The LA has two phases of release. The first is a half life of about 1 1/2 hours and the second phase about 6 1/2 hours. So it would seem you're getting a much more gradual release with Retard because both are a 50 mg pill.
Posted by atmlady on January 28, 2008, at 20:33:11
In reply to Re: Trivastal LA vs Retard, posted by bulldog2 on January 28, 2008, at 14:47:40
Day 4 on Ixel, day 10 on Trivastal
This Trivastal is so funny in how it enhances pleasure. I can go all day long doing normal things and not feel any different. But then some little thing - a song on the radio perhaps - will just affect me profoundly. I get a huge rush of pleasure and I'm like "This song is soooooo great!!!" Last night I had a sweet potato with dinner and felt like it was the best sweet potato I ever had in my life - it was sooooooo good! Then I checked myself - wait a minute, that's the trivastal.
It's weird that this effect is not constant. It just comes out of the blue. How come when I'm doing dishes or laundry I don't feel like this is the most fun EVER? It's like, if you already find pleasure in something - a type of food or a certain song - the trivastal enhances that. But it doesn't make you feel pleasure over things that you're just kinda "whatever" about.....
Then again, there are plenty of songs that I love and foods that I love that I don't get a rush over at all. I don't really get that.
Posted by clipper40 on January 28, 2008, at 20:57:30
In reply to Trivastal Musings, posted by atmlady on January 28, 2008, at 20:33:11
That is strange how it increases your pleasure some of the time but not all of the time. I already can get pleasure from things, especially music. If it can enhance that, then great. If not, no problem... as long as it can give me some motivation!!!
What dosage of Ixel are you on now? Any other reactions to that to report?
Posted by atmlady on January 30, 2008, at 20:42:47
In reply to Re: Trivastal Musings » atmlady, posted by clipper40 on January 28, 2008, at 20:57:30
Hi, Clipper! LOVE the Ixel. LOVE LOVE LOVE it. Just now at the end of week 1 and boy does it work! I'm going to wait another week before I decide to propose to whoever it was that invented Ixel, just to make sure I am not foolishly infatuated with it ;)
The NE boost is very powerful, and I do have some of the usual side effects related to that - supressed appetite, rapid heartbeat sometimes, mild hot-flashy feelings, sometimes a bit dizzy if I stand up fast. But NO PROBLEMS sleeping, oddly enough. I wake up feeling great.
I am thinking I might discontinue the Trivastal at some point, as a test, because it seems like my thinking is a bit clearer as the Trivastal wears off. Plus, how much of my love for Ixel is due to Trivastal making me fall in love with things like sweet potatoes and Three Dog Night? It would be interesting to see what Ixel is like on its own ....
Posted by clipper40 on January 30, 2008, at 22:35:59
In reply to Re: Trivastal Musings » clipper40, posted by atmlady on January 30, 2008, at 20:42:47
Wow, you certainly seem to have hit the jackpot lately!!! How much Ixel are you taking now?
I don't think I could handle all of that NE - my heart starts racing with the tiniest amount. But I'm wondering if a small amount might do me some good...
Posted by atmlady on January 31, 2008, at 6:59:43
In reply to Re: Ixel Musings » atmlady, posted by clipper40 on January 30, 2008, at 22:35:59
Hwy, Clipper - I take 2 of the 50mg caplets, but they make 25mg caplets too. They feel squishy, like powder is inside, so you might be able to go even lower if you break the caps .....
Posted by clipper40 on January 31, 2008, at 12:30:29
In reply to Re: Ixel Musings » clipper40, posted by atmlady on January 31, 2008, at 6:59:43
Thanks again. Please continue to update us on how you do with just the Ixel. I'm very interested in what each has contributed to your current wellness.
I think I said this before, but it's so nice to hear success stories.BTW, in 2-3 weeks I'll be trying the Trivastal myself. Wish me luck. No, on second thought, wish me motivation!
Posted by elanor roosevelt on February 1, 2008, at 0:11:23
In reply to Re: Ixel Musings » atmlady, posted by clipper40 on January 31, 2008, at 12:30:29
atm lady
i understand that lexapro was very good for you for a whilelexapro gave me an upbeat me for a while
i am already on trivastal 50x2, thinking about upping it. the pleasure/joy increase is reaching a plateau
maybe even going downhill
i ordered ixelhope it works as well for me as it seems to be for you
Posted by bulldog2 on February 3, 2008, at 2:01:03
In reply to ATMLady:Ixel + trivastal, posted by elanor roosevelt on February 1, 2008, at 0:11:23
> atm lady
> i understand that lexapro was very good for you for a while
>
> lexapro gave me an upbeat me for a while
>
> i am already on trivastal 50x2, thinking about upping it. the pleasure/joy increase is reaching a plateau
>
> maybe even going downhill
> i ordered ixel
>
> hope it works as well for me as it seems to be for youSeem to be building up a tolerance to trivastal.No longer notice anything on 50 mg..
Posted by atmlady on February 3, 2008, at 23:07:47
In reply to ATMLady:Ixel + trivastal, posted by elanor roosevelt on February 1, 2008, at 0:11:23
Hi, you two - I noticed a lessening of the trivastal pleasure rush just recently too - a plateau like Eleanor said, and I was at 150mg. I wasn't too hot on taking more. Plus I had a headache that I was pretty sure was from the trivastal. Decided to cut back.
So today I skipped my noon dose and only took 100 mg of trivastal all day, plus the 100 mg of ixel. Ended up taking my 6pm cocktail (50 ixel + 50 trivastal only) at 4:30 instead of 6pm 'cause I could really feel the difference! You know how you feel when withdrawing form an SSRI or wellbutrin? - whatever word explains that is what I felt today.
I always felt that trivastal pleasure rush very intermittently and unexpectedly but less and less during the past few days. More bad side effects (headache) than good in the past two days, or so it seemed like, so I decided to cut back. Today was kinda blah compared to yesterday, but 1,000,000,000,000,000 times better than two weeks ago. Today, I feel really normal. Not drugged, not pushed up, not pulled down, not artificial - just normal. Maybe it's a tolerance thing, maybe it's just getting used to a new "normal". I am still more Chatty Cathy than Mr. Spock, happy in a content sort of way, not in a "OMG, this sweet potato is the bomb, I need to buy 50 pounds of sweet potatoes" kind of way. If that makes any sense.
Still loving the ixel very much. Eleanor, be sure to take it with some food during the first week as it can make you feel a bit queasy. Also, I have noticed some constipation - probably because I am not eating so much.
A day like today - so normal, not on top of the world with a song in my heart and a rush of pleasure over seeing or hearing or tasting something fabulous, is sort of ...... blah. I make a point to remind myself of when I had those morbid thoughts that frightened me, that crushing fatigue, that hopelessness, the sleeplessness. So much better now. Like night and day!
ATMlady
Posted by elanor roosevelt on February 5, 2008, at 9:27:27
In reply to Re: ATMLady:Ixel + trivastal - bulldog + » elanor roosevelt, posted by atmlady on February 3, 2008, at 23:07:47
Today was kinda blah compared to yesterday, but 1,000,000,000,000,000 times better than two weeks ago. Today, I feel really normal. Not drugged, not pushed up, not pulled down, not artificial - just normal.
So this is where you have to really keep that reference of how you felt two weeks ago to understand where you are now
Sounds like you are doing well
Posted by ATMlady on February 7, 2008, at 17:45:20
In reply to Re: ATMLady:Ixel + trivastal - bulldog +, posted by elanor roosevelt on February 5, 2008, at 9:27:27
You are so sweet Elanor; I can't wait until you get your Ixel!
Posted by elanor roosevelt on February 21, 2008, at 16:14:33
In reply to Re: ATMLady:Ixel + trivastal - bulldog + » elanor roosevelt, posted by ATMlady on February 7, 2008, at 17:45:20
my ixel arrived at last
two-tone 50mg capsules
i'm doing some driving today so i will start tomorrow
down to trivastal at night onlywill take your advice on the ixel and take on a full stomach
anything else i should know?
Posted by Celt on February 27, 2008, at 10:36:38
In reply to Trivastal and Ixel - End of Day 2, So far So Good, posted by atmlady on January 26, 2008, at 9:22:39
What exactly does the addition of Ixel do when taking Trivastal? Trivastal for me has had great antianxiety properties, but leaves me lethargic and foggy headed. I have taken Ixel previously but it pooped out rapidly.
Posted by atmlady on February 27, 2008, at 21:36:09
In reply to Re: Trivastal and Ixel, what does combo do?, posted by Celt on February 27, 2008, at 10:36:38
Hi, Celt - In taking Ixel and Trivastal together I was trying to mimic the effects of Wellbutrin and Lexapro together, in other words, affect SE, NE and dopamine. I took the combo about two weeks and was feeling good, but was also kinda foggy headed which is not good for schoolwork. Then I happened to finally receive the provigil I'd ordered in the mail. Provigil being a dopamine re-uptake inhibitor and Trivistal being a dopamine agonist, I had ordered both (and some others) to experiment with the Ixel.
So one day (same day I just happened to take my laptop into the shop for a new hard drive and so was incommunicado with psychobabble for a while) I subbed the provigil for the trivistal and "Katie bar the door", as the saying goes. I guess it's been about a month now, and life has just exploded. I finally felt good enough to get off my duff and get a part-time job (I'm a full-time student too) and between those two obligations I am going, going, going. Holy moly!
I do miss the great sleep I was having with the Trivistal, the deep, long naps and the pleasant and vivid dreams; I had said in previous posts that it was mildly stimulating - oh ha ha ha - what does a depressed person know about feeling stimulated?
But this provigil is, man o man, like dynamite, for me anyway. I'm only taking 100mg a day with my 100mg ixel. Finally getting some stuff done, and mood is pretty good. Not sleeping much, but not seeming any worse the wear because of it. My psychiatrist seemed to think the combo was OK; wrote me a script for the provigil.
So that's where I'm at these days, and I apologize to everyone for the disappearing act - life has just been on fast-forward for me this past month!
Posted by bulldog2 on March 4, 2008, at 11:23:33
In reply to Now it's Ixel and Provigil; and apologies » Celt, posted by atmlady on February 27, 2008, at 21:36:09
> Hi, Celt - In taking Ixel and Trivastal together I was trying to mimic the effects of Wellbutrin and Lexapro together, in other words, affect SE, NE and dopamine. I took the combo about two weeks and was feeling good, but was also kinda foggy headed which is not good for schoolwork. Then I happened to finally receive the provigil I'd ordered in the mail. Provigil being a dopamine re-uptake inhibitor and Trivistal being a dopamine agonist, I had ordered both (and some others) to experiment with the Ixel.
>
> So one day (same day I just happened to take my laptop into the shop for a new hard drive and so was incommunicado with psychobabble for a while) I subbed the provigil for the trivistal and "Katie bar the door", as the saying goes. I guess it's been about a month now, and life has just exploded. I finally felt good enough to get off my duff and get a part-time job (I'm a full-time student too) and between those two obligations I am going, going, going. Holy moly!
>
> I do miss the great sleep I was having with the Trivistal, the deep, long naps and the pleasant and vivid dreams; I had said in previous posts that it was mildly stimulating - oh ha ha ha - what does a depressed person know about feeling stimulated?
>
> But this provigil is, man o man, like dynamite, for me anyway. I'm only taking 100mg a day with my 100mg ixel. Finally getting some stuff done, and mood is pretty good. Not sleeping much, but not seeming any worse the wear because of it. My psychiatrist seemed to think the combo was OK; wrote me a script for the provigil.
>
> So that's where I'm at these days, and I apologize to everyone for the disappearing act - life has just been on fast-forward for me this past month!No more trivastal?
Posted by atmlady on March 4, 2008, at 21:12:21
In reply to Re: Now it's Ixel and Provigil; and apologies, posted by bulldog2 on March 4, 2008, at 11:23:33
Nope - have not taken the Trivastal in a few weeks and I have TONS of it now in my medicine cabinet! What can I say, the Provigil just clicked with me - was exactly what (I think) I needed - and I have no desire to change a thing I'm doing because I feel like I've got the cocktail that works for me (for now anyway).
Never in 10 million years would I have ever thought I'd do well with a stimulant, with the insomnia I've suffered these past few years. I ordered the provigil only because it also worked on dopamine, like trivastal and mirapex, just to experiment as I moved from wellbutrin (lots of dopamine action) to ixel (no dopamine action). But, wow! I am up and working and can think and am not crying, and I can sleep at night, and I can orgasm, and I'm not eating 5,000 calories a day. So I'm like, not wanting to change a thing right now as you might imagine!
Posted by bulldog2 on March 9, 2008, at 15:21:58
In reply to Re: Now it's Ixel and Provigil; and apologies » bulldog2, posted by atmlady on March 4, 2008, at 21:12:21
I myself would try Ixel to see if it gave me extra energy. I think if I combined ixel with provigil my anxiety would go thru the roof. But glad it's working for you.
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Dr. Bob is Robert Hsiung, MD,
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