Psycho-Babble Medication Thread 1121935

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Depression in some women linked to a single enzyme

Posted by Hugh on March 21, 2023, at 13:01:08

Premenopausal women who suffer from depresson are much more likely to have low levels of estradiol than premenopausal women who aren't depressed. The depressed women's microbiome was found to degrade estradiol far more quickly than the microbiome of women who weren't depressed. Perhaps premenopausal women who are depressed would be especially good candidates for fecal transplant, or for the FDA-approved fecal drug Rebyota.

https://medicalxpress.com/news/2023-03-source-depression-linked-enzyme.html

Re: Depression in some women linked to a single enzyme

Posted by SLS on March 22, 2023, at 10:07:10

In reply to Depression in some women linked to a single enzyme, posted by Hugh on March 21, 2023, at 13:01:08

Hi, Hugh.

> Premenopausal women who suffer from depresson are much more likely to have low levels of estradiol than premenopausal women who aren't depressed. The depressed women's microbiome was found to degrade estradiol far more quickly than the microbiome of women who weren't depressed. Perhaps premenopausal women who are depressed would be especially good candidates for fecal transplant, or for the FDA-approved fecal drug Rebyota.
>
> https://medicalxpress.com/news/2023-03-source-depression-linked-enzyme.html

Do you know whether or not there is a corresponding reduction in testosterone for males with depression?

- Scott

Re: Depression in some women linked to a single enzyme » SLS

Posted by Hugh on March 23, 2023, at 15:22:44

In reply to Re: Depression in some women linked to a single enzyme, posted by SLS on March 22, 2023, at 10:07:10

Hi Scott,

Low testosterone, especially low free testosterone, can cause depression. I found this thread about it:

http://www.dr-bob.org/babble/20130828/msgs/1051148.html

> Hi, Hugh.
>
> > Premenopausal women who suffer from depresson are much more likely to have low levels of estradiol than premenopausal women who aren't depressed. The depressed women's microbiome was found to degrade estradiol far more quickly than the microbiome of women who weren't depressed. Perhaps premenopausal women who are depressed would be especially good candidates for fecal transplant, or for the FDA-approved fecal drug Rebyota.
> >
> > https://medicalxpress.com/news/2023-03-source-depression-linked-enzyme.html
>
> Do you know whether or not there is a corresponding reduction in testosterone for males with depression?
>
>
> - Scott

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