Psycho-Babble Medication Thread 1119302

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Keep an eye out for zuranolone for depression.

Posted by SLS on April 8, 2022, at 15:00:36

Hi.

Zuranolone is an oral medication related brexanolone, the "post-partum" drug. The problem with brexanolone is that it must be administered as continuous IV infusion over 60 hours.

Both drugs act as a GABA-A receptor positive allosteric modulator. It increases the activity of GABA neurons.

https://www.medscape.com/viewarticle/971633?spon=12&uac=41170BN&impID=4148783&sso=true&faf=1&src=WNL_mdpls_220408_mscpedit_psych

- Scott

Re: Keep an eye out for zuranolone for depression. » SLS

Posted by Jay2112 on April 8, 2022, at 22:24:33

In reply to Keep an eye out for zuranolone for depression., posted by SLS on April 8, 2022, at 15:00:36

> Hi.
>
> Zuranolone is an oral medication related brexanolone, the "post-partum" drug. The problem with brexanolone is that it must be administered as continuous IV infusion over 60 hours.
>
> Both drugs act as a GABA-A receptor positive allosteric modulator. It increases the activity of GABA neurons.
>
> https://www.medscape.com/viewarticle/971633?spon=12&uac=41170BN&impID=4148783&sso=true&faf=1&src=WNL_mdpls_220408_mscpedit_psych
>
>
> - Scott

Hey Scott,

How's it going? I do think it is interesting that they took a supplement, pregnenolone, off the market here in Canada, that works in similar ways.

Just IMwarpedHO.. :)

Jay

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