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Dr. Bob is Robert Hsiung, MD,
[email protected]Shown: posts 1 to 17 of 17. This is the beginning of the thread.
Posted by Jeroen on August 7, 2020, at 15:23:44
I've decide to give minocycline 50 mg + NAC 600 mg
and a strong pro biotic to protect my gut from the anti bioticany ideas NAC 600 mg is for the detox it will increase the herx heimer for 6 hours or longer before it goes better :(
my meds i take currently are
Abilify 20 mg
Nobiten 5 mg (half a pill in morning)
Clonazepam for seizures from the abilify
added this friday, Minocycline 50 mg (once a day)NAC 600 mg twice daily for anti biotic resistance, detox liver, herx heimer reaction
Prolardii GR caps strong pro biotic
am I good friends? I will go trough a drama otherwise :(
Posted by SLS on August 11, 2020, at 14:05:32
In reply to I've decide to give minocycline 50 mg + NAC 600 mg, posted by Jeroen on August 7, 2020, at 15:23:44
Good luck, Jeroen. Sounds like an interesting plan.
- Scott
Posted by Jeroen on August 11, 2020, at 15:33:31
In reply to Re: I've decide to give minocycline 50 mg + NAC 600 mg, posted by SLS on August 11, 2020, at 14:05:32
but didnt see your nick on recent posts
the NAC 600 mg gives me a slight anti depressant effect its good but weird...
should I up to 1200 mg so twice daily 600 mg, that i can be sure those biofilms are taken care off
Posted by Hugh on August 12, 2020, at 0:30:22
In reply to I've decide to give minocycline 50 mg + NAC 600 mg, posted by Jeroen on August 7, 2020, at 15:23:44
Low-dose aspirin (81 mg) might go well with minocycline.
Posted by undopaminergic on August 12, 2020, at 2:59:07
In reply to Re: I've decide to give minocycline 50 mg + NAC 600 mg, posted by Hugh on August 12, 2020, at 0:30:22
> Low-dose aspirin (81 mg) might go well with minocycline.
Why 81 exactly?
-undopaminergic
Posted by Hugh on August 12, 2020, at 9:24:12
In reply to Re: I've decide to give minocycline 50 mg + NAC 600 mg, posted by undopaminergic on August 12, 2020, at 2:59:07
That's just the dose low-dose aspirin is sold as, at least in the US. A regular dose of aspirin, taken daily, is more likely to irritate the stomach, or to thin the blood too much. Minocycline, combined with low-dose aspirin, seems to work well as an anti-inflammatory in people with bipolar disorder.
https://www.jwatch.org/na46040/2018/02/09/low-dose-aspirin-and-minocycline-adjunctive-treatments
Posted by SLS on August 12, 2020, at 9:25:08
In reply to Re: I've decide to give minocycline 50 mg + NAC 600 mg, posted by Hugh on August 12, 2020, at 0:30:22
> Low-dose aspirin (81 mg) might go well with minocycline.
For me, minocycline produced a significant improvement in my bipolar depression. I stopped taking it when I developed dark pigmentation in my feet and lower legs. I took it for over a year before the condition developed. That's common. I'm glad most of the hyperpigmentation has disappeared.
- Scott
Posted by SLS on August 13, 2020, at 20:40:39
In reply to I've decide to give minocycline 50 mg + NAC 600 mg, posted by Jeroen on August 7, 2020, at 15:23:44
Hi, Jeroen.
This was recently published by Dr. Robert Post of the NIH:
"The antioxidant N-acetylcysteine (NAC) helps depression, anxiety, and irritability, and is effective at treating habit-related behaviors such as trichotillomania (compulsive hair-pulling), obsessive-compulsive disorder (OCD), and drug use, including specifically reducing marijuana use in adolescents. A typical dose is 500600 mg capsules, one capsule twice a day for one week, then two capsules in the morning and two in the evening thereafter."
Good luck.
- Scott
Posted by SLS on August 13, 2020, at 20:44:15
In reply to I've decide to give minocycline 50 mg + NAC 600 mg, posted by Jeroen on August 7, 2020, at 15:23:44
Sorry, Jeroen.
My pasting of the quote was flawed. It should read:
"A typical dose is 500 mg or 600 mg capsules, one capsule twice a day for one week, then two capsules in the morning and two in the evening thereafter."
- Scott
Posted by Jeroen on August 14, 2020, at 3:31:41
In reply to Pasting error. Sorry. » Jeroen, posted by SLS on August 13, 2020, at 20:44:15
Already feel better for the moment
No adverse effects for the moment
Posted by Hugh on August 14, 2020, at 16:03:23
In reply to Re: I've decide to give minocycline 50 mg + NAC 600 mg » Hugh, posted by SLS on August 12, 2020, at 9:25:08
Scott,
I remember you posting about how much minocycline was helping you. I'm sorry to hear that you can no longer take it. It's so disappointing to find a helpful treatment, and then have to discontinue it because of unpleasant side effects.
> > Low-dose aspirin (81 mg) might go well with minocycline.
>
> For me, minocycline produced a significant improvement in my bipolar depression. I stopped taking it when I developed dark pigmentation in my feet and lower legs. I took it for over a year before the condition developed. That's common. I'm glad most of the hyperpigmentation has disappeared.
>
>
> - Scott
>
>
>
>
Posted by Jeroen on August 14, 2020, at 16:25:40
In reply to Re: I've decide to give minocycline 50 mg + NAC 600 mg » SLS, posted by Hugh on August 14, 2020, at 16:03:23
To SLS i remember that too of course
:( what was your dose? im on 50 mg once a day
Posted by SLS on August 15, 2020, at 18:08:55
In reply to To SLS i remember that too of course, posted by Jeroen on August 14, 2020, at 16:25:40
> To SLS i remember that too of course
> :( what was your dose? im on 50 mg once a dayI wish I had access to my notes today, but I'm out of town. I doubt that it was much less than the maximum recommended dosage.
- Scott
Posted by Jeroen on August 17, 2020, at 6:24:56
In reply to Re: To SLS i remember that too of course » Jeroen, posted by SLS on August 15, 2020, at 18:08:55
I don't understand this Scott, I'm taking 50 mg of minocycline it worked like a charm in the past, once a day i know its a low dose its been 3 days but it hasnt kicked in ;( ;(
What do you recommend 100 mg once a day?
Posted by Jeroen on August 17, 2020, at 6:31:03
In reply to Re: To SLS i remember that too of course » Jeroen, posted by SLS on August 15, 2020, at 18:08:55
;( ;( it hasnt kicked in or even restored my libido scott i really dont know whats going on with these meds
Posted by SLS on August 18, 2020, at 22:03:31
In reply to I'm using NAC 600 mg twice daily too, posted by Jeroen on August 17, 2020, at 6:31:03
> ;( ;( it hasnt kicked in or even restored my libido scott i really dont know whats going on with these meds
If you can, take a step back and catch your breath. It's not easy, but you need to reduce your anxiety and guard against making impulsive decisions. I have always been impatient, and it has caused me to make some bad decisions.
I don't have my notes, but I think I was taking 200 mg/day of minocycline. Minocycline might help depression by reducing brain inflammation.
As long as you don't have side effects, I think you should raise the dosage to 100 mg twice a day. I don't think it is necessary to titrate gradually. Minocycline is often started as a single 200 mg dose (loading dose) followed by 100 mg twice a day.
I have become interested in a drug called Caplyta (lumateperone). It is used as an antipsychotic, but acts to decrease glutamate activity. It is also a potent 5-HT2a receptor antagonist. There is some D2 antagonism, but it does not bind as strongly.
- Scott
Posted by SLS on August 26, 2020, at 23:57:21
In reply to Re: I'm using NAC 600 mg twice daily too » Jeroen, posted by SLS on August 18, 2020, at 22:03:31
Error: "decrease" should be "increase".
"I have become interested in a drug called Caplyta (lumateperone). It is used as an antipsychotic, but acts to INCREASE glutamate activity."
Sorry.
Blocking D1 receptors results in the stimulation of glutamatergic tracts.
In addition, lumateperone is being studied as a treatment for bipolar depression.
- Scott
This is the end of the thread.
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