Psycho-Babble Medication Thread 1102636

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Combining Stimulants?

Posted by bleauberry on December 29, 2018, at 8:09:20

I was surfing around yesterday looking for info on "Ritalin - Lyme" and "Ritalin hypo-arousal" "Ritalin depression" "Ritalin hypo-executive functioning" "Ritalin anhedonia" and also similar searches for Modafinil.

Several times I stumbled across situations where doctors had prescribed combinations of Modafinil+Ritalin or Modafinil+Adderall. These cocktails worked better than the individual ingredients. Some of these were stand-alone stimulant therapies while others had low doses of ssris, benzos, or antipsychotics also.

I had never heard of combining stimulants. But if you think about it, since they do have different mechanisms, it could make sense. Especially for patients who's primary symptoms are clustered in the realm of anhedonia, hypo-motivation, hypo-arrousal and generalized tiredness.

It was interesting that in these stories the patients had decades of inadequate treatment with antidepressants and common psych meds before they turned to stimulants, and that when they did turn to stimulants, the responses were profound and rapid.

Personally the best combo I was ever on was 20mg Prozac + 5mg Zyprexa + Modafinil (don't recall the dose). The best mono therapy I've ever had was Ritalin.

In my studies yesterday the general consensus was that for any patients considered aged with ongoing health issues of a wide variety (everything from psych to diabetes to fibromyalgia to lyme to chronic fatigue to cancer and more) Ritalin or the other stimulants, or combinations of them, are more beneficial to quality of life than other standard psychiatric medications.

 

Re: Combining Stimulants?

Posted by Christ_empowered on December 29, 2018, at 20:45:39

In reply to Combining Stimulants?, posted by bleauberry on December 29, 2018, at 8:09:20

I could see it being beneficial. modafanil could boost the traditional upper and help keep the doses of the Schedule II drugs lower. Plus...it has a long half life, right? That might make 1x daily dosing possible and reduce the severity of the crash once the Ritalin or amphetamine wears off. just a random thought.

interesting post. i saw a vintage ritalin ad, pushing it for depression...because of serious adverse effects from the 'antidepressants.' i guess nothing has changed?

 

Re: Combining Stimulants?

Posted by DrDad on December 30, 2018, at 15:38:33

In reply to Re: Combining Stimulants?, posted by Christ_empowered on December 29, 2018, at 20:45:39

Interesting info and I may talk to doc about adding modafinal to my dexedrine. I alternated days between various formulations of amphetamine and methylphenidate for years after finding out that I couldn't take either daily without them becoming ineffective. Recently I had to stop methylphenidate due to excess side effects so I've been looking around for options.

 

Re: Combining Stimulants?

Posted by linkadge on January 1, 2019, at 14:10:48

In reply to Re: Combining Stimulants?, posted by DrDad on December 30, 2018, at 15:38:33

Yeah, unfortunately, psychiatry has abandoned dopaminergic strategies for depression and pursued serotonin up the ying-yang (with only marginal results).

Nobody starts a revolution on SSRIs. The powers that be can keep us complacent.

Linkadge


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