Psycho-Babble Medication Thread 1071364

Shown: posts 1 to 24 of 24. This is the beginning of the thread.

 

Naurex´s Glyx-13 repeated dosing: Very promising

Posted by Lamdage22 on September 21, 2014, at 6:14:14

http://naurex.com/wp-content/uploads/2014/05/Naurex_Clinical_Advances-2014.05.06.pdf

 

Re: Naurex´s Glyx-13 repeated dosing: Very promising

Posted by Lamdage22 on September 21, 2014, at 6:26:03

In reply to Naurex´s Glyx-13 repeated dosing: Very promising, posted by Lamdage22 on September 21, 2014, at 6:14:14

I seriously hope that developments like this will fix my life in the next 5 years!

I remember when i first came to the US. The euphoria was huge...
New won freedom after school. Tons of friends and acquaintances from all over the world.

It was so awesome. I want that euphoria back. I want my life back.

Im just waiting in line for a decent treatment. Thats all i do :/

 

Re: Naurex´s Glyx-13 repeated dosing: Very promising

Posted by Lamdage22 on September 21, 2014, at 6:28:38

In reply to Re: Naurex´s Glyx-13 repeated dosing: Very promising, posted by Lamdage22 on September 21, 2014, at 6:26:03

http://spryliving.com/articles/new-depression-drug-offers-hope/

 

Re: Naurex´s Glyx-13 repeated dosing: Very promising

Posted by SLS on September 21, 2014, at 8:19:18

In reply to Re: Naurex´s Glyx-13 repeated dosing: Very promising, posted by Lamdage22 on September 21, 2014, at 6:28:38

I would prefer to see NRX-1074 (Naurex) approved. It works the same way, but is taken orally.


- Scott

 

Re: Naurex´s Glyx-13 repeated dosing: Very promising

Posted by Lamdage22 on September 21, 2014, at 8:55:33

In reply to Re: Naurex´s Glyx-13 repeated dosing: Very promising, posted by SLS on September 21, 2014, at 8:19:18

I know, i wouldnt care as long as i had remission.

Id take a shot every day if that would result in remission.

I only need to see that my doctor diagnoses me "Schizophrenia AND Depression" not " Schizophrenia"...
That way my future doctor could prescribe Glyx-13 (in Germany). US medication AND off-label use narrows down doctors willing to prescribe unneccessarily. I really do have both.

Of course id prefer NRX-1074, but i really dont mind the injections! Im only thinking "remission", nothing else.

 

Re: Naurex´s Glyx-13 repeated dosing: Very promising » Lamdage22

Posted by SLS on September 21, 2014, at 9:56:55

In reply to Re: Naurex´s Glyx-13 repeated dosing: Very promising, posted by Lamdage22 on September 21, 2014, at 8:55:33

> Of course id prefer NRX-1074, but i really dont mind the injections! Im only thinking "remission", nothing else.

Injections or I.V.?


- Scott

 

Re: Naurex´s Glyx-13 repeated dosing: Very promising

Posted by Lamdage22 on September 21, 2014, at 11:02:31

In reply to Re: Naurex´s Glyx-13 repeated dosing: Very promising » Lamdage22, posted by SLS on September 21, 2014, at 9:56:55

I think IV.

1mg of this stuff is like 180 dollars...

Jeez.

 

Re:

Posted by linkadge on September 21, 2014, at 13:20:43

In reply to Re: Naurex´s Glyx-13 repeated dosing: Very promising, posted by Lamdage22 on September 21, 2014, at 11:02:31

I notice that I can take Effexor (under 37.5mg) with mangnesium and zinc as needed. Sometimes, once a week or twice a week works well.

I would recommend that anyone with depression considers augmenting with magnesium and zinc.

Linkadge

 

Re:

Posted by Lamdage22 on September 21, 2014, at 14:25:16

In reply to Re:, posted by linkadge on September 21, 2014, at 13:20:43

Its really not funny.. i feel like crap.

All day every day. My life is disappearing. Friends are disappearing, my confidence is disappearing, joy, i don't know what that is.

Lets not even talk about motivation.

 

Re:

Posted by Lamdage22 on September 21, 2014, at 14:28:03

In reply to Re:, posted by Lamdage22 on September 21, 2014, at 14:25:16

Im pretty darn angry about circumstances in my life.

 

How long until these drugs might be available?

Posted by rovers95 on September 21, 2014, at 16:33:04

In reply to Naurex´s Glyx-13 repeated dosing: Very promising, posted by Lamdage22 on September 21, 2014, at 6:14:14

> http://naurex.com/wp-content/uploads/2014/05/Naurex_Clinical_Advances-2014.05.06.pdf
>
>

Does anyone know how long we will have to wait? I see GLYX-13 is being fast-tracked?

Rover

 

Re: How long until these drugs might be available? » rovers95

Posted by Phillipa on September 21, 2014, at 21:47:06

In reply to How long until these drugs might be available?, posted by rovers95 on September 21, 2014, at 16:33:04

Maybe never might not pass trials and the FDA is now concentrating on new antibiotic since other don't work. P

 

Re: How long until these drugs might be available?

Posted by Lamdage22 on September 22, 2014, at 5:22:20

In reply to How long until these drugs might be available?, posted by rovers95 on September 21, 2014, at 16:33:04

> > http://naurex.com/wp-content/uploads/2014/05/Naurex_Clinical_Advances-2014.05.06.pdf
> >
> >
>
> Does anyone know how long we will have to wait? I see GLYX-13 is being fast-tracked?
>
> Rover

2015 or 2016 if it will pass.

 

Re: How long until these drugs might be available?

Posted by Lamdage22 on September 22, 2014, at 5:27:10

In reply to Re: How long until these drugs might be available? » rovers95, posted by Phillipa on September 21, 2014, at 21:47:06

Phillipa,

why so pessimistic?

 

Re: Naurex´s Glyx-13 repeated dosing: Very promising

Posted by Lamdage22 on September 23, 2014, at 5:47:50

In reply to Re: Naurex´s Glyx-13 repeated dosing: Very promising, posted by Lamdage22 on September 21, 2014, at 11:02:31

This may be like the penicillin of psychiatry. Who knows?

As of now: Response rates up to double of that of SSRI and related drugs and response magnitude also double.

I am psyched. I hope this picture will hold true through phase III trials.

Maybe it will even be beneficial for psychosis? At the very least, i hope it will not have a tendency to cause psychosis.

All AD´s i had tried, they either don't work or cause psychosis. Well, to be fair, Mirtazapine had an effect and did not cause psychosis. Nightmares though.

Glyx-13 type drugs may be the exception!

 

Re: Naurex´s Glyx-13 repeated dosing: Very promising

Posted by SLS on September 23, 2014, at 8:40:35

In reply to Re: Naurex´s Glyx-13 repeated dosing: Very promising, posted by Lamdage22 on September 23, 2014, at 5:47:50

> This may be like the penicillin of psychiatry. Who knows?
>
> As of now: Response rates up to double of that of SSRI and related drugs and response magnitude also double.
>
> I am psyched. I hope this picture will hold true through phase III trials.
>
> Maybe it will even be beneficial for psychosis? At the very least, i hope it will not have a tendency to cause psychosis.
>
> All AD´s i had tried, they either don't work or cause psychosis. Well, to be fair, Mirtazapine had an effect and did not cause psychosis. Nightmares though.
>
> Glyx-13 type drugs may be the exception!

Infusions are very expensive and inconvenient. Hopefully, Naurex will consider offering an intranasal delivery system.


- Scott

 

Re: How long until these drugs might be available? » Lamdage22

Posted by Phillipa on September 23, 2014, at 9:33:21

In reply to Re: How long until these drugs might be available?, posted by Lamdage22 on September 22, 2014, at 5:27:10

I apologize Lamadge I was feeling sorry for myself no excuse and had just been in a huge fight with husband. No excuse but I owe you an explanation. Phillipa

 

Re: How long until these drugs might be available?

Posted by Lamdage22 on September 23, 2014, at 9:39:24

In reply to Re: How long until these drugs might be available? » Lamdage22, posted by Phillipa on September 23, 2014, at 9:33:21

Im sorry about that, Phillipa. An iDevice sync problem just woke up my own anger.

As for the expensive infusions: Thats not good.

If they do an open label study with inclusion criteria that i meet, i may travel to the US once again and do it.

I would like to.

Also my kind of wealthy father could help me. If it becomes a success, it will be available cheaplier over time.
Sorry if the grammar is off here;)

 

Re: How long until these drugs might be available? » Lamdage22

Posted by SLS on September 23, 2014, at 9:57:46

In reply to Re: How long until these drugs might be available?, posted by Lamdage22 on September 23, 2014, at 9:39:24

> Im sorry about that, Phillipa. An iDevice sync problem just woke up my own anger.
>
> As for the expensive infusions: Thats not good.
>
> If they do an open label study with inclusion criteria that i meet, i may travel to the US once again and do it.
>
> I would like to.
>
> Also my kind of wealthy father could help me. If it becomes a success, it will be available cheaplier over time.
> Sorry if the grammar is off here;)

Your grammar is excellent.

:-)

I have always had an immense amount of admiration and respect for people who have learned to speak English as a second language.


- Scott

 

Re: How long until these drugs might be available?

Posted by Lamdage22 on September 23, 2014, at 14:07:28

In reply to Re: How long until these drugs might be available? » Lamdage22, posted by SLS on September 23, 2014, at 9:57:46

So this is how youd say that?

I like learning english. It opens horizons.

So i have a solid lorazepam buzz now and will do surgery tomorrow with benzo midazolam IV:)

Sounds like fun to me

 

Re: How long until these drugs might be available? » Lamdage22

Posted by Phillipa on September 23, 2014, at 20:29:38

In reply to Re: How long until these drugs might be available?, posted by Lamdage22 on September 23, 2014, at 9:39:24

Lamadge thanks for understanding again I do apologize and do hope you can travel here and receive any meds you may need. Phillipa

 

Re: Naurex´s Glyx-13 should i enroll this study?

Posted by Lamdage22 on September 24, 2014, at 13:27:17

In reply to Re: Naurex´s Glyx-13 repeated dosing: Very promising, posted by SLS on September 23, 2014, at 8:40:35

http://clinicaltrials.gov/show/NCT01844726

 

Re: How long until these drugs might be available?

Posted by Lamdage22 on September 27, 2014, at 5:01:27

In reply to How long until these drugs might be available?, posted by rovers95 on September 21, 2014, at 16:33:04

> > http://naurex.com/wp-content/uploads/2014/05/Naurex_Clinical_Advances-2014.05.06.pdf
> >
> >
>
> Does anyone know how long we will have to wait? I see GLYX-13 is being fast-tracked?
>
> Rover

Way too long..

 

Re: How long until these drugs might be available?

Posted by Lamdage22 on September 27, 2014, at 11:54:12

In reply to Re: How long until these drugs might be available?, posted by Lamdage22 on September 27, 2014, at 5:01:27

Way way way too long.

1mg is 130 eur.

So i could buy one dose for the cheap price of 50.000 eur per dose. Thats awesome!


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