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Dr. Bob is Robert Hsiung, MD,
[email protected]Shown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by europerep on October 14, 2010, at 14:34:30
ok, this only relates to meds indirectly, but I think it's more appropriate here than anywhere else..
surely you all know how a kid might ask why exactly as many things happen on a given day as will fit into the newspaper of tomorrow.. and the answer is of course that the newspaper selects its news. now one might ask why exactly the amount of scientific articles is being written as will fit into weekly/monthly/etc. scientific journals out there, and of course these journals do their selecting too.. I remember a JCP issue where there was a list of all the reviewers, who were said to sift through hundreds of articles for each issue, in order to choose the most interesting 5 or 6 or 7 of them.. in scientific databases like sciencedirect.com, one can almost exclusively access published articles. so what happens with all the articles that are not being published? I am not refering to clinical studies whose results are not being released by a pharma company (like in the reboxetine thread above), but about "regular" studies, by university groups, that just don't make it into a journal. do they appear on PubMed, or somewhere else? does anybody know anything about that?
Posted by Phillipa on October 15, 2010, at 10:45:24
In reply to where is all the UNpublished science?, posted by europerep on October 14, 2010, at 14:34:30
No good question. Phillipa
Posted by bleauberry on October 15, 2010, at 16:28:10
In reply to where is all the UNpublished science?, posted by europerep on October 14, 2010, at 14:34:30
I think the powerhorse unpublished studies number in the thousands. They are the single patient studies, purely anecdotal, happening all over the country with creative open minded clinicians. These are the cases where mothers of autistic children are providing researchers with clues of where to study...what works in the real world for them and what doesn't. Doctors curing longstanding resistant depression by way of following up on a modest hunch of lyme disease instead of depression, despite not being able to know for sure in advance. On and on. Lots of things like that. Candida, another one. Food intolerances that were unsuspected. Simple stuff actually, but totally ignored. These are the unpublished studies that really have meaning behind them in the real world with with people in real time....not in the theoretical white coat world.
Posted by europerep on October 16, 2010, at 14:58:10
In reply to Re: where is all the UNpublished science?, posted by bleauberry on October 15, 2010, at 16:28:10
Well, what keeps these doctors from communicating their results, writing case reports, etc.? That is unWRITTEN science..
What I mean is rather neuroscientific studies of whether a certain drug binds to cloned in vitro opioid/NMDA/xyz receptors, etc...
Posted by bleauberry on October 18, 2010, at 19:05:49
In reply to Re: where is all the UNpublished science? » bleauberry, posted by europerep on October 16, 2010, at 14:58:10
> Well, what keeps these doctors from communicating their results, writing case reports, etc.? That is unWRITTEN science..
>
> What I mean is rather neuroscientific studies of whether a certain drug binds to cloned in vitro opioid/NMDA/xyz receptors, etc...Well, you've seen the waiting room. Unless a doctor is absolutely obsessed with love for his/her job, I think he/she is going home at 5pm, not writing any research. They certainly can't be doing any research with a backlog of patients waiting to see them.
The unpublished stuff. I don't know. I guess it might be interesting. But would it in any way be beneficial? I don't think so. The stuff that turns out to be really helpful is the stuff that people themselves discover. Such as LDN. No unpublished studies discovered that gem. Ok, let's assume every unpublished study is suddenly on your table to read. Now what? Do you think any of them are going to mean you will be cured in few weeks, because now you this or that has affinity for some receptor or something? Personally i don't see that.
Even the peer reviewed heralded published studies don't do us much good when it comes to actually getting better.
This is the end of the thread.
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