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Dr. Bob is Robert Hsiung, MD,
[email protected]Shown: posts 1 to 7 of 7. This is the beginning of the thread.
Posted by rovers95 on August 24, 2010, at 18:40:28
hey, this drug (ketoconazole) has shown potential for treating depression symptoms in those with high cortisol levels, has anyone used this themselves or know of anyone or any pdoc that has experience with it?
many thanks
rover
Posted by BrainDamage on August 25, 2010, at 8:23:17
In reply to Ketaconazole (Nizoral) as treatment for depression, posted by rovers95 on August 24, 2010, at 18:40:28
Firstly I should say that I've never taken Ketaconazole
I'm interested in Cortisol lowering therapies though
Something that concerns me is that Ketaconazole has Testosterone lowering properties
I would have though that this would be a problem for men taking the drugAnother thing that interests me is how people respond to Anticortisol treatments.
If you have a positive response to something that lowers Cortisol, does that mean that your Cortisol levels are to high?
Posted by rovers95 on August 25, 2010, at 11:11:09
In reply to Re: Ketaconazole (Nizoral) as treatment for depression, posted by BrainDamage on August 25, 2010, at 8:23:17
> Firstly I should say that I've never taken Ketaconazole
>
> I'm interested in Cortisol lowering therapies though
>
> Something that concerns me is that Ketaconazole has Testosterone lowering properties
> I would have though that this would be a problem for men taking the drug
>
> Another thing that interests me is how people respond to Anticortisol treatments.
>
> If you have a positive response to something that lowers Cortisol, does that mean that your Cortisol levels are to high?Well those who response to ketoconazole therapy appear to be those who are hypercortisolesimic and DMT non suppressors.
I have some and i really want to give it a try!!
Rover
Posted by SLS on August 25, 2010, at 11:40:25
In reply to Re: Ketaconazole (Nizoral) as treatment for depression, posted by rovers95 on August 25, 2010, at 11:11:09
Hi Rover.
> Well those who response to ketoconazole therapy appear to be those who are hypercortisolesimic and DMT non suppressors.
>
> I have some and i really want to give it a try!!Do you have any idea how long it takes to work?
- Scott
Posted by rovers95 on August 25, 2010, at 12:58:21
In reply to Re: Ketaconazole (Nizoral) as treatment for depression » rovers95, posted by SLS on August 25, 2010, at 11:40:25
> Hi Rover.
>
> > Well those who response to ketoconazole therapy appear to be those who are hypercortisolesimic and DMT non suppressors.
> >
> > I have some and i really want to give it a try!!
>
> Do you have any idea how long it takes to work?
>
>
> - Scott4 weeks in this study, but it started to work from the 1st dose onwards (i got the full pdf through athens). The second just states the results after 6 weeks.
http://www.biopsychiatry.com/ketoconazole.htm
http://www.ncbi.nlm.nih.gov/pubmed/8480829
i think it inhibits the P450 enzyme, so SSRI's, benzos and most APs are out, but i think some tricyclics MIGHT be ok??
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2042747/
rover
Posted by ed_uk2010 on August 25, 2010, at 13:56:44
In reply to Re: Ketaconazole (Nizoral) as treatment for depres » SLS, posted by rovers95 on August 25, 2010, at 12:58:21
Due to the risk of severe liver damage, ketoconazole is no longer a commonly used antifungal (its primary use). Just something to bear in mind.
Posted by bleauberry on August 25, 2010, at 15:39:53
In reply to Ketaconazole (Nizoral) as treatment for depression, posted by rovers95 on August 24, 2010, at 18:40:28
Well, it also kills yeast, fungus, and candida, which are believed by many to be epidemic problems underlying symptoms such as depression, fatigue, and brain fog. For sure I felt a ton better while on Diflucan.
This is the end of the thread.
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