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Dr. Bob is Robert Hsiung, MD,
[email protected]Shown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by TriedEveryDrug on December 23, 2009, at 17:33:09
I have tried various things that allegedly improve cognition one way or another. (I probably have some cognitive impairment either from ADD or bpII, but I'm talking about things that improve cognition in healthy people)
Aricept - did absolutely nothing for me.
Piracitam - nothing
Provigil - nothing
Stims - made my cognition worse!
PhosphatidylSerine - one brand (NeuroPS) seemed to work for about two weeks... then poop. (other brands, like GNC, did jack)
Omega-3 fish oil - nada
Does anyone know -- has anything been proven to improve cognition, let's say in otherwise healthy people?In the research I have done, various compounds have studies that claim various improvements... but maybe these studies are flawed somehow or another. I always keep my eye out for new studies and what not, but I'm starting to think this notion of being able to enhance cognition via some drug or nutrient is bunk...
Thanks
Posted by janejane on December 25, 2009, at 8:49:39
In reply to Cognitive enhancers... Is anything proven to work?, posted by TriedEveryDrug on December 23, 2009, at 17:33:09
Don't know much about this area, but noticed you didn't mention rhodiola rosea. Might be something to look into.
Posted by bleauberry on December 25, 2009, at 12:35:57
In reply to Cognitive enhancers... Is anything proven to work?, posted by TriedEveryDrug on December 23, 2009, at 17:33:09
Nothing is proven to work in anything.
Well, I guess it is fairly well proven that if we take two ends of a broken bone and stick them together they will heal up.
When it comes to drugs, herbs, supplements, and foods, nothing is proven. Everyone's biology and genes vary too much. What will do benefit for one will do harm to another.
Everything is experimental. Nothing is proven. That is unless you consider "60% of the sample achieved a 50% improvement of symptoms"...well, if that's a definition of "proven", then I guess a lot of things are proven, including most of the substances you listed. To me, those statistics are not proof of anything, except that they are proof they are 5% to 15% more effective than a sugar pill.
Posted by TriedEveryDrug on December 25, 2009, at 12:40:54
In reply to Re: Cognitive enhancers... Is anything proven to work?, posted by bleauberry on December 25, 2009, at 12:35:57
Fine... if we have to be officious and precise here, then what I mean is "generally accepted as efficacious".
Posted by bleauberry on December 25, 2009, at 12:59:09
In reply to Cognitive enhancers... Is anything proven to work?, posted by TriedEveryDrug on December 23, 2009, at 17:33:09
Well you are talking about healthy people. I have only studied what helps ill people. In that category the following come to mind, though I know there are others I am not recalling at this time.
Hydergine.
Trials of the "other" racitams, they each of unique qualities and synergies.
Savella.
Siberian Ginseng tincture...give it 3 months.
Cordyceps.
Bacopa.
Gotu Kola.
Rhodiola.
Wheat-free, gluten-free, dairy-free food choices (eat for health instead of pleasure).
Low Dose Naltrexone.
Japanese Knotwood (with its Resveratrol).
Trials of DLPA, Tyrsoine...if neuros are being gobbled up too fast, none of the drugs or supplements have enough there to work with. Kinid of like trying to dam up a river or change the direction of the flow when the river has barely a trickle. Even a mere 100mg day DLPA can boost reserves a lot over several weeks.
> I have tried various things that allegedly improve cognition one way or another. (I probably have some cognitive impairment either from ADD or bpII, but I'm talking about things that improve cognition in healthy people)
>
> Aricept - did absolutely nothing for me.
> Piracitam - nothing
> Provigil - nothing
> Stims - made my cognition worse!
> PhosphatidylSerine - one brand (NeuroPS) seemed to work for about two weeks... then poop. (other brands, like GNC, did jack)
> Omega-3 fish oil - nada
>
>
Posted by TriedEveryDrug on December 28, 2009, at 20:13:15
In reply to Re: Cognitive enhancers... Is anything proven to work?, posted by bleauberry on December 25, 2009, at 12:59:09
Nice list.
As far as milnacipran/savella, my understanding is that it is a SERT/NET agonist or reuptake inhibitor.
Or does this drug have other actions as well?
How long would someone have to trial the *racitams to see an effect? I have found these compounds to have little effect on me. Maybe they need to be mixed with hydergine?Interesting about the DLPA, Tyrsoine, too. Maybe Deplin as well?
Thanks
> Well you are talking about healthy people. I have only studied what helps ill people. In that category the following come to mind, though I know there are others I am not recalling at this time.
>
> Hydergine.
> Trials of the "other" racitams, they each of unique qualities and synergies.
> Savella.
> Siberian Ginseng tincture...give it 3 months.
> Cordyceps.
> Bacopa.
> Gotu Kola.
> Rhodiola.
> Wheat-free, gluten-free, dairy-free food choices (eat for health instead of pleasure).
> Low Dose Naltrexone.
> Japanese Knotwood (with its Resveratrol).
> Trials of DLPA, Tyrsoine...if neuros are being gobbled up too fast, none of the drugs or supplements have enough there to work with. Kinid of like trying to dam up a river or change the direction of the flow when the river has barely a trickle. Even a mere 100mg day DLPA can boost reserves a lot over several weeks.
>
This is the end of the thread.
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