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Dr. Bob is Robert Hsiung, MD,
[email protected]Shown: posts 1 to 10 of 10. This is the beginning of the thread.
Posted by inanimate peanut on December 22, 2009, at 19:22:59
What is the official upper limit for Parnate (from the PDR)? Who on here has doses higher than that? Sorry, I tried to google this and it just kept bringing up our previous posts. Also, if anyone has any articles that talk about the upper limit of Parnate, that would b very useful. Thanks!
Posted by inanimate peanut on December 22, 2009, at 19:27:54
In reply to Parnate upper limit, posted by inanimate peanut on December 22, 2009, at 19:22:59
Upper limit 60mg!!!!!!! according to the PDR! I know a lot of you are on more than that successfully.
Posted by willey on December 22, 2009, at 19:36:38
In reply to Re: Parnate upper limit, posted by inanimate peanut on December 22, 2009, at 19:27:54
> Upper limit 60mg!!!!!!! according to the PDR! I know a lot of you are on more than that successfully.
Not so much the pdr but more so the msds sheet for parnate states this.But remeber they iniatly had 30 as the max dose,then revivsed it to 60.
I take ease because i have numerous published articles about how effective high dose parnate can be,in fact some stating the sugges dose is simply wrong and not high enough.From the most validated info i have,it states parnate as so
60 therputic,raised first to 90,and for treatment resintance cases the final dose which is common is 125 to a max of no more then 200 mg.
I have not seen in any writing a dose above 200 mg used or recomended but have again and again seen the common being 100-125 and less common but still effective 200.Its not uncommon for under 100 mg to not be sufficient,which makes it sad as its rare no matter what data u bring to ur doc chances are high he will not even phantom the thought of going above 60.
Posted by ace on December 22, 2009, at 20:06:19
In reply to Parnate upper limit, posted by inanimate peanut on December 22, 2009, at 19:22:59
> What is the official upper limit for Parnate (from the PDR)? Who on here has doses higher than that? Sorry, I tried to google this and it just kept bringing up our previous posts. Also, if anyone has any articles that talk about the upper limit of Parnate, that would b very useful. Thanks!
Check this out mate:http://www.ncbi.nlm.nih.gov/pubmed/2710808
Posted by inanimate peanut on December 22, 2009, at 20:50:19
In reply to Re: Parnate upper limit, posted by willey on December 22, 2009, at 19:36:38
Can you give me links to those articles that you have to say that?
Posted by inanimate peanut on December 22, 2009, at 20:54:17
In reply to Re: Parnate upper limit » inanimate peanut, posted by ace on December 22, 2009, at 20:06:19
Thanks so much for the article. Anything I can show her like that will be helpful!
Posted by ace on December 22, 2009, at 20:59:04
In reply to Re: Parnate upper limit » ace, posted by inanimate peanut on December 22, 2009, at 20:54:17
Posted by Phillipa on December 23, 2009, at 0:12:08
In reply to Re: Parnate upper limit » ace, posted by inanimate peanut on December 22, 2009, at 20:54:17
When you googled parnate did you click the right side? As the left which it's on is for old posts only not the internet. And someone said if in parenthesis you get a more indepth search. Good luck Phillipa
Posted by Phillipa on December 23, 2009, at 0:17:23
In reply to Re: Parnate upper limit, posted by Phillipa on December 23, 2009, at 0:12:08
Here's one. Phillipa
Posted by willey on December 23, 2009, at 7:22:11
In reply to Re: Parnate upper limit » ace, posted by inanimate peanut on December 22, 2009, at 20:54:17
> Thanks so much for the article. Anything I can show her like that will be helpful!
Thanks to ace for providing that,but thats the main one,and it holds credintial as its source is from the ncbi.Now doing a search youll come across a lot more,however most will be user comments,and articles not published which wont hold as much water as the above.
But like phillipa said in her own way,play with keywords on google,example parnate high dose,parnate effective dose ranger,etc,search google groups as well,if you r willing to use user comments then you can fine many many results,many,i also take a look in a bit to see whati can find.
The company initialy set the high for 30 mg,then after time and results,officialy revised it to 60 as well as revised the no no food list.
With these official changes,combined with actualy speaking to them a number of times,my theory is they stay at the lower ranger because
-- Its safer to stay a lower range in general,even if most will respond to a higher dose simply because staying lower will just ensure more safety which is understandable.
--- The med is old,little pharmcology was ever known,or still learned of its action,just recently it was snuck in its profile that it affected gaba b.But maois due to there wide range of action on so many levels opposed to being in any way selective make them hard to understand drugs.
The sad part is to be on a more effective dose you have to hope you have a good doc to work with you,or give up on the drug,or and its aganist many peoples views which would be to do what it takes to be on a effective dose or parnate.
Last i hope you feel safer knowing the info in regard to the effivness of the high dose comes from a legit reputable source which was the ncbi.
Thanks again to ace cause i had forgot where i had seen that info.
This is the end of the thread.
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