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Dr. Bob is Robert Hsiung, MD,
[email protected]Shown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by matt sanz on March 30, 2009, at 1:10:28
I just have a quick question about switching meds. This week I took my last doses of two meds, Ludiomil which is a tricyclic type of antidepressant and Trazodone, also for depression. My last day of taking these meds was Monday. I started on Effexor XR on Friday. I was supposed to wait a week in between my last dose of the first meds and starting the Effexor, but instead I waited only 4 days. Should the fact that I only had a 4 day wash-out period before starting the Effexor have any impact on how well it is going to work? I'm just a little worried. Thanks for your responses.
-Matt
Posted by SLS on March 30, 2009, at 7:02:41
In reply to Switching meds question, please help., posted by matt sanz on March 30, 2009, at 1:10:28
> I just have a quick question about switching meds. This week I took my last doses of two meds, Ludiomil which is a tricyclic type of antidepressant and Trazodone, also for depression. My last day of taking these meds was Monday. I started on Effexor XR on Friday. I was supposed to wait a week in between my last dose of the first meds and starting the Effexor, but instead I waited only 4 days. Should the fact that I only had a 4 day wash-out period before starting the Effexor have any impact on how well it is going to work? I'm just a little worried. Thanks for your responses.
That is a very intelligent concern, but I don't believe that there is any medical basis for the effect you describe. Starting Effexor a few days earlier should not affect in any way its efficacy. Plenty of people do cross-titrations and even direct switches without any waiting period.Can you describe for me your experiences with Ludiomil?
Thanks.
- Scott
Posted by Zana on March 30, 2009, at 12:34:15
In reply to Re: Switching meds question, please help. » matt sanz, posted by SLS on March 30, 2009, at 7:02:41
I think the concern here and the reason for the wash-out period may be serotonin syndrome. Wikipedia had a good description of the symptoms. Check it out and see if you are experiencing anything that they describe.
How long have you been on the Effexor?
I agree with Scott. I don't think starting the Effexor a little early will impact the effects of the med but I would be a little concerned about the impact of having all three med in your system at the same time and might err on the side of caution and wait the full week to start the Effexor.
Zana
Posted by matt sanz on March 30, 2009, at 20:46:48
In reply to Re: Switching meds question, please help., posted by Zana on March 30, 2009, at 12:34:15
I was only on Ludiomil for four weeks. I didn't notice any benefits so my doc told me to come off it.
Posted by desolationrower on March 31, 2009, at 1:34:50
In reply to Re: Switching meds question, please help., posted by matt sanz on March 30, 2009, at 20:46:48
it would be pretty hard to get SS with maprotoline and another ssri.
-d/r
Posted by tensor on April 1, 2009, at 8:51:22
In reply to Switching meds question, please help., posted by matt sanz on March 30, 2009, at 1:10:28
No, there is no need to worry.
This is the end of the thread.
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