Psycho-Babble Medication Thread 878685

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nardil - blood sugar

Posted by g_g_g_unit on February 7, 2009, at 6:09:48

sorry to add yet another nardil thread. i have been quite tolerant w/r/t to se's, yet this blood sugar issue is bothering me. basically, if i go more than an hour or two without eating something, i fall into a terrible hypoglycemic state, which it can take a while to recover from. i have brought this up to my doctor and he said he can't see how the nardil would be doing this, which is strange because pubmed returns numerous abstracts on how hydrazines affect glucose. i am following a low GI diet which helps with hunger somewhat, yet like i say, if i go without eating, the repercussions are pretty bad. is this a side-effect that most likely won't go away? now 2 days @ 60mg. feel really relaxed, almost to a point of sublime indifference, yet no other positive social benefits (i.e. talkativeness), no positive cognitive changes (still have brain fog, memory's terrible, etc.), incredibly tired during the day...

 

Re: nardil - blood sugar

Posted by SLS on February 7, 2009, at 6:27:54

In reply to nardil - blood sugar, posted by g_g_g_unit on February 7, 2009, at 6:09:48

Hi GGG_U

> sorry to add yet another nardil thread. i have been quite tolerant w/r/t to se's, yet this blood sugar issue is bothering me. basically, if i go more than an hour or two without eating something, i fall into a terrible hypoglycemic state, which it can take a while to recover from. i have brought this up to my doctor and he said he can't see how the nardil would be doing this, which is strange because pubmed returns numerous abstracts on how hydrazines affect glucose. i am following a low GI diet which helps with hunger somewhat, yet like i say, if i go without eating, the repercussions are pretty bad. is this a side-effect that most likely won't go away? now 2 days @ 60mg. feel really relaxed, almost to a point of sublime indifference, yet no other positive social benefits (i.e. talkativeness), no positive cognitive changes (still have brain fog, memory's terrible, etc.), incredibly tired during the day...

You'll need perhaps 3 weeks at 60mg if it is going to work at that dosage. Rule of thumb for Nardil dosage is 1mg of Nardil for every 1kg of body weight. I'll let you do the math. 1kg = 2.2 lbs. becomes xxx pounds divided by 2.2. A lot of people end up at 75mg.

Regarding blood sugar, Nardil (phenelzine) can make a mess of glucose/insulin dynamics. It has to do with glucose disposal rate produced by hypersecretion of insulin. Hypogylcemia is a documented side effect of Nardil. You already know that. I don't doubt that this is what is happening here. However, you might as well give this side effect time to mitigate. If not, there is always Parnate.

I actually developed hypoglycemia upon discontinuing Nardil 90mg. It just likes to play with insulin levels - either on the way up or the way down. It took about 2-3 weeks for my blood sugar to normalize.

It is disappointing when a doctor doesn't know everything but thinks he does, isn't it? It is a question of attitude.


- Scott

 

Re: nardil - blood sugar

Posted by g_g_g_unit on February 7, 2009, at 6:50:09

In reply to Re: nardil - blood sugar, posted by SLS on February 7, 2009, at 6:27:54

thanks for your reply SLS. like i say - i hate to post continually, but as i'm sure you know, med trials can be frustrating experiences, especially when you have a doc who's dismissive and uninformed (thus making it seem like the patient is the one at fault for experiencing 'non-existent' side-effects; thank god the internet). i had heard about the 1mg per 1kg of body weight rule before; i weigh 63kg, so 60mg should hopefully be my optimal dose. the main benefit from nardil has in fact been that it's bought me enough time to get myself into therapy, which i think will provide the longest-lasting benefit for my condition. if nardil does fail, my plan was to go drug-free for a while to try and return to a baseline. otherwise, i am keeping parnate in mind

 

Re: nardil - blood sugar » g_g_g_unit

Posted by janejane on February 7, 2009, at 10:48:43

In reply to Re: nardil - blood sugar, posted by g_g_g_unit on February 7, 2009, at 6:50:09

I've never taken Nardil so I can't comment about that, but I've always had a tendency to crash if I don't eat every few hours. I recently started taking 200 mcg chromium daily (166% of DV) after reading that it can help regulate blood sugar. I'm not sure, but I think I notice a difference. It might be something to look into if it continues to be an issue with you.

 

Re: nardil - blood sugar

Posted by Phillipa on February 7, 2009, at 10:54:10

In reply to Re: nardil - blood sugar » g_g_g_unit, posted by janejane on February 7, 2009, at 10:48:43

Also small amounts of protein every four hours. For Blood sugar stabalization. I've taken nardil either. Phillipa

 

Re: nardil - blood sugar

Posted by bulldog2 on February 7, 2009, at 11:31:27

In reply to nardil - blood sugar, posted by g_g_g_unit on February 7, 2009, at 6:09:48

> sorry to add yet another nardil thread. i have been quite tolerant w/r/t to se's, yet this blood sugar issue is bothering me. basically, if i go more than an hour or two without eating something, i fall into a terrible hypoglycemic state, which it can take a while to recover from. i have brought this up to my doctor and he said he can't see how the nardil would be doing this, which is strange because pubmed returns numerous abstracts on how hydrazines affect glucose. i am following a low GI diet which helps with hunger somewhat, yet like i say, if i go without eating, the repercussions are pretty bad. is this a side-effect that most likely won't go away? now 2 days @ 60mg. feel really relaxed, almost to a point of sublime indifference, yet no other positive social benefits (i.e. talkativeness), no positive cognitive changes (still have brain fog, memory's terrible, etc.), incredibly tired during the day...

Since Nardil affects the body's ability to handle sugar I would go on a high protein, moderate fat and low carb diet. Make sure the carbs are complex.

 

Re: nardil - blood sugar

Posted by janejane on February 7, 2009, at 16:55:22

In reply to Re: nardil - blood sugar, posted by bulldog2 on February 7, 2009, at 11:31:27

Oh yeah, protein definitely helps. And about the chromium - some multivitamins include it so you may be getting enough already. (Mine didn't.) Good luck!

 

Re: nardil - blood sugar

Posted by g_g_g_unit on February 7, 2009, at 17:42:43

In reply to Re: nardil - blood sugar » g_g_g_unit, posted by janejane on February 7, 2009, at 10:48:43

> I've never taken Nardil so I can't comment about that, but I've always had a tendency to crash if I don't eat every few hours. I recently started taking 200 mcg chromium daily (166% of DV) after reading that it can help regulate blood sugar. I'm not sure, but I think I notice a difference. It might be something to look into if it continues to be an issue with you.

I've suffered from hypoglycemia in the past as well, yet the time limit I have before crashing is drastically reduced on nardil. a magnesium complex i take contains chromium, but i haven't noticed a huge difference using it; if the nardil ends up working in all other respects - with only the blood sugar symptoms persisting - then maybe i'll try stand-alone chromium supplementation


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