![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
[email protected]Shown: posts 1 to 10 of 10. This is the beginning of the thread.
Posted by FrequentFryer on November 11, 2008, at 4:23:55
I have been taking Anti-D's for about 6 years now (mainly for Social Anxiety / Depression) but have tried a hell of allot of combinations in that time because I cycle them quite fast usually only stay on them for 2 - 3 months, then change once they poop out.
Favourites would be Nardil & Effexor
I have been on Nardil 90mg for about three months now and am again thinking about quitting it because the Hyperhydrosis, Weight gain, Constipation and sex side effects barely make up for the tiny mood boost.
I dunno do you guys reckon I should.
A: Lower the dose to 45mg to tollerate the side effects and just stick with it.B: I always go straight to max dose 90mg's of Nardil and get a bit too high / manic once it kicks in for the first to months. Maybe I should have a med detox then restart Nardil on 45 mg and when it poops out go to 75 then 90 and try and maintain a longer start up effect.
C: Go back to Effexor so atleast I don't need to worry about the side effects as bad and just stick with it.
Posted by SLS on November 11, 2008, at 6:45:13
In reply to Long Time Antidepressant Psycho Dabblers?, posted by FrequentFryer on November 11, 2008, at 4:23:55
You have a difficult decision to make. I really don't have any strong feelings as to what you should do. I would only add that Marplan is an effective MAOI whose side effects are milder than those of Nardil.
If you go back to Effexor, perhaps you can try adding Wellbutrin and/or nortriptyline.
- Scott
Posted by azalea on November 11, 2008, at 23:04:59
In reply to Long Time Antidepressant Psycho Dabblers?, posted by FrequentFryer on November 11, 2008, at 4:23:55
Antidepressant poop-out may indicate that you would benefit from a mood stabilizer. There is some thought that rapid but not sustained response to antidepressants is part of the bipolar spectrum.
> I have been taking Anti-D's for about 6 years now (mainly for Social Anxiety / Depression) but have tried a hell of allot of combinations in that time because I cycle them quite fast usually only stay on them for 2 - 3 months, then change once they poop out.
>
> Favourites would be Nardil & Effexor
>
> I have been on Nardil 90mg for about three months now and am again thinking about quitting it because the Hyperhydrosis, Weight gain, Constipation and sex side effects barely make up for the tiny mood boost.
>
> I dunno do you guys reckon I should.
>
> A: Lower the dose to 45mg to tollerate the side effects and just stick with it.
>
> B: I always go straight to max dose 90mg's of Nardil and get a bit too high / manic once it kicks in for the first to months. Maybe I should have a med detox then restart Nardil on 45 mg and when it poops out go to 75 then 90 and try and maintain a longer start up effect.
>
> C: Go back to Effexor so atleast I don't need to worry about the side effects as bad and just stick with it.
>
Posted by Maxime on November 12, 2008, at 18:50:59
In reply to Long Time Antidepressant Psycho Dabblers?, posted by FrequentFryer on November 11, 2008, at 4:23:55
You could try to augment the meds with mood stabilisers, anti-psychotics or some T3.
If those things don't work have you thought about having ECT?
maxime
Posted by kenny7 on November 14, 2008, at 17:09:28
In reply to Re: Long Time Antidepressant Psycho Dabblers?, posted by SLS on November 11, 2008, at 6:45:13
just TRY and get off effexor
Posted by FrequentFryer on November 15, 2008, at 0:24:26
In reply to Re: Long Time Antidepressant Psycho Dabblers?, posted by SLS on November 11, 2008, at 6:45:13
Cheers for the input.
It is a tough one, I am gonna stick with the Nardil @ 90 for now.
Do you know if there is much difference between the popular Dopamine agonists? could you recommend one considering $ I would like to import Carbergoline (Im in Australia) but i'ts pretty expensive.
Would Bromocriptine or I dunno Mirapex do pretty much the same thing for mood and sex do ya reckon?> You have a difficult decision to make. I really don't have any strong feelings as to what you should do. I would only add that Marplan is an effective MAOI whose side effects are milder than those of Nardil.
>
> If you go back to Effexor, perhaps you can try adding Wellbutrin and/or nortriptyline.
>
>
> - Scott
Posted by FrequentFryer on November 15, 2008, at 0:32:34
In reply to Re: Long Time Antidepressant Psycho Dabblers? » FrequentFryer, posted by azalea on November 11, 2008, at 23:04:59
Yeah I take approx 150mg of seroquel a day. I never notice myself get manic but my uncle is bipolar, Lamictal is definatly up there at the top of my list.
> Antidepressant poop-out may indicate that you would benefit from a mood stabilizer. There is some thought that rapid but not sustained response to antidepressants is part of the bipolar spectrum.
>
> > I have been taking Anti-D's for about 6 years now (mainly for Social Anxiety / Depression) but have tried a hell of allot of combinations in that time because I cycle them quite fast usually only stay on them for 2 - 3 months, then change once they poop out.
> >
> > Favourites would be Nardil & Effexor
> >
> > I have been on Nardil 90mg for about three months now and am again thinking about quitting it because the Hyperhydrosis, Weight gain, Constipation and sex side effects barely make up for the tiny mood boost.
> >
> > I dunno do you guys reckon I should.
> >
> > A: Lower the dose to 45mg to tollerate the side effects and just stick with it.
> >
> > B: I always go straight to max dose 90mg's of Nardil and get a bit too high / manic once it kicks in for the first to months. Maybe I should have a med detox then restart Nardil on 45 mg and when it poops out go to 75 then 90 and try and maintain a longer start up effect.
> >
> > C: Go back to Effexor so atleast I don't need to worry about the side effects as bad and just stick with it.
> >
>
>
Posted by FrequentFryer on November 15, 2008, at 0:35:00
In reply to Re: Long Time Antidepressant Psycho Dabblers? » FrequentFryer, posted by Maxime on November 12, 2008, at 18:50:59
What do you think about ect? Iv'e heard its fairly dodgy unreliable, dose it work best on a particular type of mental disorder?
> You could try to augment the meds with mood stabilisers, anti-psychotics or some T3.
>
> If those things don't work have you thought about having ECT?
>
> maxime
Posted by SLS on November 15, 2008, at 6:07:12
In reply to Re: Long Time Antidepressant Psycho Dabblers? » SLS, posted by FrequentFryer on November 15, 2008, at 0:24:26
Hi.
I think using a dopamine receptor agonist is a treatment with a rather low probability of success. It does not tend to make people feel very well for extended periods of time. I have seen it help initially, though. If you choose to try one of these compounds, stay away from cabergoline and pergolide. They act to damage heart valves (valvulopathy) via agonizing 5-HT2b receptors. Although there is still debate about how often this occurs at low dosages, if you have alternatives, I would try those first. Mirapex (pramipexole) might have the best chance of helping. Unlike bromocriptine, which is restricted to D2 receptor agonism in the striatum and related structures, pramipexole works to stimulate both D2 and D3 receptors in the limbic system. The limbic system is responsible for feelings of reward and elevated mood.
Since none of us have a crystal ball for fortune telling, I would not presume to issue a recommendation to avoid Mirapex or Requip due to a lack of efficacy. You might very well benefit from them to make them worth keeping in your treatment regime.
Good luck.
- Scott> Cheers for the input.
> It is a tough one, I am gonna stick with the Nardil @ 90 for now.
> Do you know if there is much difference between the popular Dopamine agonists? could you recommend one considering $ I would like to import Carbergoline (Im in Australia) but i'ts pretty expensive.
> Would Bromocriptine or I dunno Mirapex do pretty much the same thing for mood and sex do ya reckon?
>
> > You have a difficult decision to make. I really don't have any strong feelings as to what you should do. I would only add that Marplan is an effective MAOI whose side effects are milder than those of Nardil.
> >
> > If you go back to Effexor, perhaps you can try adding Wellbutrin and/or nortriptyline.
> >
> >
> > - Scott
>
>
Posted by elanor roosevelt on November 16, 2008, at 22:36:53
In reply to Re: Long Time Antidepressant Psycho Dabblers?, posted by kenny7 on November 14, 2008, at 17:09:28
> just TRY and get off effexor
I just had a great withdrawal from effexor
nightmares every night but so vivid and interesting that i didn't mindbut that was it
not everyone suffers terribly getting off effexor
i've done it twice
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
[email protected]
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.