Psycho-Babble Medication Thread 860701

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Tofisopam/Emandaxin or Grandaxin Any Experience?

Posted by Mishal on November 4, 2008, at 2:17:53


Hi there,

I read a comment here in 2004, someone commented on this wonderful benzo called TOFISOPAM. It has been said to have anxiolytic and stimulating properties, something unusual with currently available benzos. Besides, no tolerance or withdrawal noticed.

What attracted me is posterer mentioned of its positive effects on motivation, sociability etc. Sad, this drug is not available either in Europe or US.

Here is Wiki extract on it:

"Tofisopam is not approved for sale in the United States or Canada. However, Vela Pharmaceuticals of New Jersey is developing the D- enantiomer (dextofisopam) as a treatment for irritable bowel syndrome with moderate efficacy demonstrated in clinical trials so far."

Any idea with anyone here on whether we will ever be able to get hold on this stuff?

 

Re: Tofisopam/Emandaxin or Grandaxin Any Experience? » Mishal

Posted by yxibow on November 5, 2008, at 22:01:37

In reply to Tofisopam/Emandaxin or Grandaxin Any Experience?, posted by Mishal on November 4, 2008, at 2:17:53

>
> Hi there,
>
> I read a comment here in 2004, someone commented on this wonderful benzo called TOFISOPAM. It has been said to have anxiolytic and stimulating properties, something unusual with currently available benzos. Besides, no tolerance or withdrawal noticed.
>
> What attracted me is posterer mentioned of its positive effects on motivation, sociability etc. Sad, this drug is not available either in Europe or US.
>
> Here is Wiki extract on it:
>
> "Tofisopam is not approved for sale in the United States or Canada. However, Vela Pharmaceuticals of New Jersey is developing the D- enantiomer (dextofisopam) as a treatment for irritable bowel syndrome with moderate efficacy demonstrated in clinical trials so far."
>
> Any idea with anyone here on whether we will ever be able to get hold on this stuff?


Probably a decade if ever since Vela was just bought out anyhow if I read correctly. Not every clinical trial gets to the market, it takes a long arduous process and a number of mental health drugs never make it.

Xanax has stimulating properties to a minor extent, thats why some people swear it has antidepressant effects.

It would be curious if any benzodiazepine ever was developed again for FDA/Canada/EMEA since the last one (Xanax) was in 1981.

-- Jay

 

Re: Tofisopam/Emandaxin or Grandaxin Any Experience?

Posted by Treehugger on November 6, 2008, at 10:32:53

In reply to Re: Tofisopam/Emandaxin or Grandaxin Any Experience? » Mishal, posted by yxibow on November 5, 2008, at 22:01:37

I tried Grandaxin a couple of years ago - It felt good, relaxing at first, but after a couple of hours I was nervous. It's stimulating effect was agitating for me. Tree


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