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Dr. Bob is Robert Hsiung, MD,
[email protected]Shown: posts 1 to 10 of 10. This is the beginning of the thread.
Posted by jms600 on September 28, 2008, at 17:20:33
Hi everyone
I'm sure I read on here some time back that one dose of Zyprexa is good for severe anxiety and real bad panic attacks/episodes.
By one dose I mean taking a single dose at the onset of a bad panic attack - as you would take a Valium or a Klonopin at the onset of a panic attack. Is this true, or does Zyprexa need to 'build up' in the body - as does an SSRI or Tricyclic??
In other words, how quick is the therapeutic effects of Zyprexa (is it as quick as a benzo or as slow as an SSRI for anxiety)??
Any thoughts anyone??
Thanks!
Posted by dbc on September 28, 2008, at 20:34:43
In reply to Can one dose of Zyprexa really help panic attacks?, posted by jms600 on September 28, 2008, at 17:20:33
I dont really see a correlation between dopamine activity and panic disorder. Seroquel might work due to its antihistamine activity simply knocking you out. I get delusion crazy from panic attacks and nothing really works properly besides benzos. Thats purely ancedotal but seems to not be far off for some people.
Strangely lamictal is pretty awsome for panic disorder in my case.
Posted by Phillipa on September 29, 2008, at 0:30:17
In reply to Re: Can one dose of Zyprexa really help panic attacks?, posted by dbc on September 28, 2008, at 20:34:43
lamictal helps your panic attacks? I tried it once and got to 50mg no side effects doesn't it act as an ad too? Xanax is the best for panic. Phillipa
Posted by llurpsienoodle on September 29, 2008, at 6:18:53
In reply to Can one dose of Zyprexa really help panic attacks?, posted by jms600 on September 28, 2008, at 17:20:33
Yep, it works for me. I take the Zydis Zyprexa, which is a instant-dissolve tablet 10mg. I have it on hand in case of emergency. It starts working in about 15 min. Basically it knocks me out and turns me into a zombie for 16 hours. Not always the ideal solution, but beats panic, in many circumstances.
-Ll
Posted by Quintal on September 29, 2008, at 10:30:35
In reply to Can one dose of Zyprexa really help panic attacks?, posted by jms600 on September 28, 2008, at 17:20:33
It will work straight away like a benzo, but it's stronger. It's quite long acting too so you'll be sedated for at least the rest of the day (and possibly into the next). I have used it for anxiety when nothing else worked, but only in small doses - like half a 2.5mg tablet, and even that's pretty heavy for me. I've also found it can also have an instant mood brightening effect.
Q
Posted by med_empowered on September 29, 2008, at 16:13:49
In reply to Re: Can one dose of Zyprexa really help panic attacks? » jms600, posted by Quintal on September 29, 2008, at 10:30:35
i mean, if you have the option.
Antipsychotics can induce sedation, reduce agitation, and make you apathetic--all of which can create a "tranquilizing" effect, especially if you keep the dose low and are fortunate enough to avoid the ill-effects of taking antipsychotics (eps, akathisia, dysphoria, cognitive and affective dulling, etc.). And there's always Neuroleptic Malignancy Syndrome...watch out for that.
Also, sometimes antipsychotics, epsecially used over the long-term, make panic *worse* or induce panic. Its probably because the dopamine blocking action creates chemically-induced Parkinson's (even before Parkinson's shows itself in muscle twitches and what not, patients will present with apathy, increased anxiety, panic attacks....basically all things that can also happen with antipsychotic usage).
Good luck.
Posted by bleauberry on September 29, 2008, at 17:15:18
In reply to Can one dose of Zyprexa really help panic attacks?, posted by jms600 on September 28, 2008, at 17:20:33
When I used to take zyprexa, it did work on panic attacks pretty fast. For me it took about an hour and really started to kick in at about 2 hours. I had been on it a long time and so the sedative side effects were gone. Also I had a much higher tolerance of it after so long. So even though it would probably last a long time for most people, it would last maybe 8 hours for me. But yeah, it was powerful against anxiety and panic. If I was ever in a situation where I just knew I needed some fast help, I would always retreat to privacy and sneak down a little extra zyprexa and be so much better it was like night and day.
But I would try xanax, and separately klonopin, first. They are just generally safer and even faster than zyprexa. If you have problems with those, then at least you can say you tried first line meds and then move on to off label meds like zyprexa.
Posted by Zyprexa on September 30, 2008, at 2:29:16
In reply to Can one dose of Zyprexa really help panic attacks?, posted by jms600 on September 28, 2008, at 17:20:33
I've found that when I quit the zyprexa I get realy anxious and panicy. This happens with in a week off it. If I take as much as 2.5mg, with in a hour I start feeling better.
Posted by yxibow on September 30, 2008, at 23:53:05
In reply to Can one dose of Zyprexa really help panic attacks?, posted by jms600 on September 28, 2008, at 17:20:33
> Hi everyone
>
> I'm sure I read on here some time back that one dose of Zyprexa is good for severe anxiety and real bad panic attacks/episodes.
>
> By one dose I mean taking a single dose at the onset of a bad panic attack - as you would take a Valium or a Klonopin at the onset of a panic attack. Is this true, or does Zyprexa need to 'build up' in the body - as does an SSRI or Tricyclic??Yes.
> In other words, how quick is the therapeutic effects of Zyprexa (is it as quick as a benzo or as slow as an SSRI for anxiety)??
>
> Any thoughts anyone??
>
> Thanks!A simple, no.
Atypicals don't really have any significant effects for several weeks and they don't build up for several months to their full potency.
A single "dose" whatever that is, would just be a antihistamine/muscarinic knockout effect, if you're not used to the medication already.
You'd wake up groggy and it wouldn't serve the best purposes. You might as well take Benadryl.
The Klonopin or Valium, as a PRN would be the best route, secondarily and not terribly effective for the specifics of panic would be a beta blocker like propranolol.
-- best wishes
-- Jay
Posted by yxibow on October 1, 2008, at 0:03:39
In reply to i'd try a benzo first..., posted by med_empowered on September 29, 2008, at 16:13:49
> i mean, if you have the option.
>
> Antipsychotics can induce sedation, reduce agitation, and make you apathetic--all of which can create a "tranquilizing" effect, especially if you keep the dose low and are fortunate enough to avoid the ill-effects of taking antipsychotics (eps, akathisia, dysphoria, cognitive and affective dulling, etc.). And there's always Neuroleptic Malignancy Syndrome...watch out for that.I know you're not a fan of antipsychotics and I'm not a fan needing to take one for my functionality, but that is a broad spectrum generalization of neuroleptics in general, though I agree EPS is a possibility even with one single dose but that usually is more with typicals than atypicals -- however, a lot of the strong atypicals can produce it too, but then even some people react with akathisia with Seroquel, so who knows.
NMS is extremely rare, and on a single dose would be one for a letter to the editor of a psychiatric journal.
> Also, sometimes antipsychotics, epsecially used over the long-term, make panic *worse* or induce panic. Its probably because the dopamine blocking action creates chemically-induced Parkinson's (even before Parkinson's shows itself in muscle twitches and what not, patients will present with apathy, increased anxiety, panic attacks....basically all things that can also happen with antipsychotic usage).Lets say I agree to disagree. Panic is also induced in some people by incredible fear and sometimes, even for a brief period, a neuroleptic can reduce that. Yes, I don't like being dulled, and I need to "experience" the world -- but at the same time, experiencing it means possibly having my complex of anxiety back. It's a touchy balance. Anyhow, that's just a very long personal journey and not to be taken as what anyone else might feel.
As for the primary posting, I would agree and noted that a benzodiazepine would probably quell it and it would be far less flattening on the system, one could go about their business instead of being sedated for 6+ hours -- and with a TCA, could be sedated for an entire day if one isn't used to it.
-- tidings
Jay
This is the end of the thread.
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