![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
[email protected]Shown: posts 3 to 27 of 27. Go back in thread:
Posted by FredPotter on November 29, 2007, at 21:53:00
In reply to Fastest Acting AD you have taken??, posted by clubfitter on November 29, 2007, at 20:05:27
Moclobemide was the fastest but also the fastest pooper
Posted by Justherself54 on November 29, 2007, at 22:01:04
In reply to Re: Fastest Acting AD you have taken??, posted by FredPotter on November 29, 2007, at 21:53:00
Lexapro was the fastest for me but pooped out like all SSRI's do. Currently on Nardil..took 13 days to kick in and I'm pretty impressed with it thus far..
Posted by FredPotter on November 29, 2007, at 22:02:39
In reply to Re: Fastest Acting AD you have taken??, posted by bleauberry on November 29, 2007, at 21:00:39
Having loaded up my nervous system gradually on 90mg per day of Nardil I'm trying to see how low I can go without recurrence of symptoms. One evening I'd obviously gone too low. Like flicking a switch I felt terrible again. So I immediately took 30mg of extra Nardil, 25 mg Nortriptyline and 300mg Niacin (I find the flush calming). Within two hours I was feeling great again. It's just that to get to this level, when topping up works in my experience, you have to build up the dose and wait. In my case 6.5 weeks. It was worth the wait. My depression and anxiety was replaced by euphoria, presumably a side effect. This lasted 2 or 3 weeks then I felt normal.
I concur with everyone who says - MAOIs should be first-line treatment for depression
Fred
Posted by sonic_gb on November 29, 2007, at 22:14:35
In reply to Re: Fastest Acting AD you have taken??, posted by FredPotter on November 29, 2007, at 21:53:00
I had exactly the same experience with Mocloemide. It was GREAT for 4-5 days and then no effect. That's why I'm hoping to get on a real MAOI to see if I get the same effect, but sustained over time.
Posted by Phillipa on November 29, 2007, at 22:46:27
In reply to Re: Fastest Acting AD you have taken?? » FredPotter, posted by sonic_gb on November 29, 2007, at 22:14:35
Luxox. Phillipa only one that does something don't know what but still here.
Posted by yxibow on November 30, 2007, at 5:34:25
In reply to Re: Fastest Acting AD you have taken??, posted by Phillipa on November 29, 2007, at 22:46:27
> Luxox. Phillipa only one that does something don't know what but still here.
Zyprexa the first time around at 5mg. After 3 days I had no use for Klonopin and I felt wonderful. Unfortunately it did cause shaky hands and I was put off by that. An atypical will stop depression in a very short course and long term transition to a fairly calming SSRI such as Luvox or Paxil which would cover anxiety and depression would be one idea.
Posted by Netch on November 30, 2007, at 6:25:26
In reply to Re: Fastest Acting AD you have taken?? » Phillipa, posted by yxibow on November 30, 2007, at 5:34:25
ethyl-EPA until it caused insomnia after 3-4 days
/Netch
Posted by B2chica on November 30, 2007, at 9:10:24
In reply to Fastest Acting AD you have taken??, posted by clubfitter on November 29, 2007, at 20:05:27
i think my saving grace medication has ALways been zyprexa...it is fast acting for me...literally within 24 hours i feel a difference.
(ex. this last time i went to the hospital, when i was admitted i literally could not physically stop crying except for a few minutes of reprieve here and there) within 24 hours i stopped...maybe partly because of hospital environment, maybe partly physical exhaustion....but quite frankly i've been on it before...i know its the med.)and also i agree about the ritalin. except that its very short acting. only helps for a few hours...better than nothing and VERY helpful if you are in a danger zone.
********
do becareful if you have ever had manic reactions to meds.
i have expecially to effexor and prozac (but don't let my responses to meds effect you....its just a cautionary note) one of those meds may work Wonders for you...just alwyas be alert for a change in your normal behavior.
best wishes
b2c.
Posted by B2chica on November 30, 2007, at 9:12:30
In reply to Re: Fastest Acting AD you have taken??, posted by Justherself54 on November 29, 2007, at 22:01:04
don't mean to hijack thread but have a question for Justherself54...
my pdoc wants me to start lexapro.
i finally got the nerve to take one this morning.
-how soon do you notice a difference?
-and do you have MDD or BP? if you have BP did you have any manic issues with this med?
-and how long before it pooped out...sorry for the 20 questions...but i appreciate any input you can give...
Thanks!!
b2c.
Posted by Maxime on November 30, 2007, at 15:41:49
In reply to Fastest Acting AD you have taken??, posted by clubfitter on November 29, 2007, at 20:05:27
Parnate ... hands down.
Maxime
Posted by clubfitter on November 30, 2007, at 17:10:09
In reply to Re: Fastest Acting AD you have taken?? » clubfitter, posted by Maxime on November 30, 2007, at 15:41:49
could you tell me more about your experience...how fast did it work for you...have you heard other stories to that effect....Parnate is exactly what i was hoping to hear...going to ask my doc for it next time...thanks!
Posted by Maxime on November 30, 2007, at 18:18:33
In reply to Re: Fastest Acting AD you have taken??)) MAXIME, posted by clubfitter on November 30, 2007, at 17:10:09
> could you tell me more about your experience...how fast did it work for you...have you heard other stories to that effect....Parnate is exactly what i was hoping to hear...going to ask my doc for it next time...thanks!
Hi
I started on 20 mg and ended up on 80 mg. After 3 days on 20 mg I could already feel the effect. I thought I was imagining it because no AD works that fast. It was acting as a stimulant. So my mood didn't lift in 3 days, but with the help of the stimulant effect I did feel better and was able to accomplish things I hadn't been about to in a while. My mood started to lift after 3 days on 30 mg.
I have heard others say the same thing about Parnate (more than with Nardil) so I am not the only one.
I hope this helps!
Maxime
Posted by Justherself54 on November 30, 2007, at 19:26:13
In reply to Re: Fastest Acting AD you have taken?? » Justherself54, posted by B2chica on November 30, 2007, at 9:12:30
> don't mean to hijack thread but have a question for Justherself54...
> my pdoc wants me to start lexapro.
> i finally got the nerve to take one this morning.
> -how soon do you notice a difference?
> -and do you have MDD or BP? if you have BP did you have any manic issues with this med?
> -and how long before it pooped out...
>
> sorry for the 20 questions...but i appreciate any input you can give...
> Thanks!!
> b2c.Hi B2c. I noticed a difference within 4-5 days..I have BP. I did experience a mild euphoria for a day or two, but nothing that concerned me..it pooped out on me after a year..that's why I'm now trying Nardil..hoping to find something that doesn't poop out after roughly the year mark..Lexapro was great for my social anxiety and I was even able to return to work until I crashed after the poop out..hope it works well for you as it did for me initially..don't remember any start-up side effects either..I found it a good med, next to Zoloft..except I suffer from the dreaded poop out syndrome! Good luck to you..keep up posted on how you're doing..
Posted by anonymoose on December 1, 2007, at 12:48:05
In reply to Fastest Acting AD you have taken??, posted by clubfitter on November 29, 2007, at 20:05:27
Mirapex. Adderall and ritalin have faster onset (immediate, significant increase in dopaminergic transmission) but have nasty long-term effects and are thus usually not sustainable.
A better approach is: What is the specific nature of your symptoms, and what underlying causes do they point to? (Serotonergic dysfunction? Dopaminergic? A combination of the two? Something else entirely??)
It's best try to treat the specific causes. Hard part is figuring out what those specific causes are. Only good ways I can think of are MRI, PET, and deductive analysis based on descriptive symptomology. For example, anxious, fearful depression points to serotonin; apathetic, anhedonic anergia points to dopamine. Overly simplistic analysis, to be sure, but better than the one-size-fits-all shot-in-the-dark approach to prescribing meds that most clinical psychiatrists rely so heavily on.
Posted by Phillipa on December 1, 2007, at 18:11:17
In reply to Re: Fastest Acting AD you have taken??, posted by anonymoose on December 1, 2007, at 12:48:05
Well then I'm serotonin as therapist said she'd call my depression agitated as pick constantly on cuticles and fear everything. Phillipa
Posted by anonymoose on December 1, 2007, at 19:15:03
In reply to Re: Fastest Acting AD you have taken?? » anonymoose, posted by Phillipa on December 1, 2007, at 18:11:17
Ever try a 5-HT2a/c antagonist like Mirtazapine? It's no wonderdrug, but its 2a/2c antagonism can be fast and very effective for driving away that constant irrational, fearful state.
Posted by Phillipa on December 1, 2007, at 19:21:45
In reply to Re: Fastest Acting AD you have taken?? » Phillipa, posted by anonymoose on December 1, 2007, at 19:15:03
Can you believe I was in the hospital and they put me on l5mg of remeron with chloral hydrate and started the valium so some xanax too. And I didn't sleep up in four hours of also 50mg of seroquel which when woke-up they repeated and I almost fainted when woke up again. End of the seroquel. Stayed on the remeron for a month with the others. Nothing no side effects just nothing. Phillipa ps must have tx resistant sleep.
Posted by Mishal on December 2, 2007, at 0:33:37
In reply to Fastest Acting AD you have taken??, posted by clubfitter on November 29, 2007, at 20:05:27
> Im very desperate here and need something to work ASAP. I've heard MAOI's work pretty fast? Is this true? Im going to talk about it with my doc. What have you tried that has worked fast? Thanks!
Fastest acting? My picks.1. Provigil (Can cause stimulant low at initial stage. No crashes after repeated dosing)
2. Stablon (Has to take 25mg TID. Can be reduced to the standard 12.5mg TID after a week or so)
3. Trivastal Retard (Notable effect after two to three days)
4. Solian (Dramatic early effects soon diminish. But subtle AD effects persist)
5. Dogmatil (Same as Solian)
Posted by stargazer2 on December 2, 2007, at 13:17:50
In reply to Re: Fastest Acting AD you have taken?? » anonymoose, posted by Phillipa on December 1, 2007, at 19:21:45
So you don't know how the Remeron would work by itself since you were on a combo of medications.
Remeron dose ranges from 15-45 for usual dosing. You perhaps could try this again alone and see what happens.
I have noticed that many of the med combinations I have taken do not give me a good idea of how any of the meds would work on their own.
I failed Marplan but I went back to my notes and saw I was on several other medications with it. In order to know whether it would really work again I would have to take it by itself.
Perhaps remeron would work for you alone, or perhaps just with the Valium, you have taken for so long, since I don't think you can come off of that without a real desire to do so and a plan to wean off it. But you really haven't given Remeron a good trial since you only took 15 mg and the other meds you took it with might have prevented it from working. There were too many ingredients in that recipe to know what was doing what.
They call that a shot gun approach. No real theory behind it, just using alot of meds to try and get any response.
Stargazer
Posted by Phillipa on December 2, 2007, at 17:45:00
In reply to Re: Fastest Acting AD you have taken??/phillipa, posted by stargazer2 on December 2, 2007, at 13:17:50
Stargazer the answer to that one is a pdoc put me on wellbutrin 150mg for a week and saw the pdoc and he thought I was manic. So sent to inpatient and they decided to try and make me sleep but since my first child I've had the same pattern of waking after four hours did it then to make sure she was still breathing. I was only l9 then. Plan at the hospital was a taper off the chloral hyrate and xanax and go on the valium first time in years. Think they gave me zoloft for depression. Phillipa
Posted by stargazer2 on December 2, 2007, at 18:24:46
In reply to Re: Fastest Acting AD you have taken??/phillipa » stargazer2, posted by Phillipa on December 2, 2007, at 17:45:00
You missed my point of the story. If you tried Remeron alone the effects may work completely differently than when you are on 3-4 other meds.
Taking many meds together may not work the same as when you are only taking one med by itself, say Remeron.Stargazer
Posted by Phillipa on December 2, 2007, at 20:07:42
In reply to Re: Fastest Acting AD you have taken??/phillipa, posted by stargazer2 on December 2, 2007, at 18:24:46
I understand but need to wait til after surgery and new pdoc in January. Full bottle never opened of remeron here in my drug cabinet. Thanks stargazer. Phillipa
Posted by stargazer2 on December 3, 2007, at 9:30:49
In reply to Re: Fastest Acting AD you have taken??/phillipa » stargazer2, posted by Phillipa on December 2, 2007, at 20:07:42
I know but is it an option (Remeron) you would try since you have such fear in trying new drugs. Will you have to stop any of your meds before surgery?
The only way someone will get better is by trial and error unless you are content with the place you are at. There's nothing worse in my book than taking something for which there is no improvement in my functioning.
Why take anything if it is not giving you some benefits, that makes no sense to me. All meds have side effects so you have to make sure your choice of meds has benefits to it even though the SE's may seem minimal, you are still affecting biochemical reactions in your body that over the long term might cause other problems.
hope your surgery goes well, is it scheduled yet?
Stargazer
Posted by tecknohed on December 3, 2007, at 19:27:46
In reply to Fastest Acting AD you have taken??, posted by clubfitter on November 29, 2007, at 20:05:27
All SSRIs (except fluoxetine & sertraline) & venlafaxine work for me on day one. But they all poop out within 2 weeks. Kind of the opposite to what they're supposed to do!
Not very helpfull I know, but a quick fix none the less.
Posted by qbsbrown on December 3, 2007, at 21:19:36
In reply to Fastest Acting AD you have taken??, posted by clubfitter on November 29, 2007, at 20:05:27
Lexapro- 3-4 days and depression is gone. Unfortunately, not good for my mania
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
[email protected]
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.