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Dr. Bob is Robert Hsiung, MD,
[email protected]Shown: posts 1 to 9 of 9. This is the beginning of the thread.
Posted by clubfitter on October 30, 2007, at 21:40:18
what is the difference between bupropion and budeprion? are they the same or are they different? thanks
Posted by yxibow on October 31, 2007, at 0:36:41
In reply to bupropion vs. budeprion-are they different?, posted by clubfitter on October 30, 2007, at 21:40:18
> what is the difference between bupropion and budeprion? are they the same or are they different? thanks
Same, just generic now, including the SR. I'm sure we can get into the generic debate and the AUC curve allowances -- whats most important with a generic if one believes they're really sensitive is to keep taking the same manufacturer. Its ultimately a personal choice how many $ a pill.
Posted by stargazer2 on October 31, 2007, at 9:22:20
In reply to Re: bupropion vs. budeprion-are they different? » clubfitter, posted by yxibow on October 31, 2007, at 0:36:41
What I think is really confusing is that with all other generic meds, there is usually only one generic name. Why are there two generic versions of wellbutrin, one called budeprion and one called Budepreion?
When I went to the pharmacy to pick up the prescription for Buproprion, the name, color and writing on the pill (Budeprion) was different. The pharmacist ensured (?) me the Budeprion was the generic of Buproprion, but he could not answer my questions about the bioequivalency of the pill.
Many former users of Buroprion are questioning the effects of the newer generic Budeprion in that they claim it does not work as well as Buproprion. The FDA is supposedly looking into these complaints.
Even though a generic has to have the same 'active' ingredients as the brand name med, the variations in pill coating and other so called 'non-active' ingredients are different enough, that the generic may dissolve and be absorbed very differently.
It is a cause for concern. I stopped taking Budepreion due to the side effects I never had with Buproprion.
Stargazer
Posted by clubfitter on October 31, 2007, at 9:52:43
In reply to Re: bupropion vs. budeprion-are they different?, posted by stargazer2 on October 31, 2007, at 9:22:20
Was the Bupropion effective for you??
Posted by Racer on October 31, 2007, at 11:51:17
In reply to Re: bupropion vs. budeprion-are they different?, posted by stargazer2 on October 31, 2007, at 9:22:20
>
> Even though a generic has to have the same 'active' ingredients as the brand name med, the variations in pill coating and other so called 'non-active' ingredients are different enough, that the generic may dissolve and be absorbed very differently.
>Actually, I think generics can be off by about 10% in either direction, which can cause trouble.
But as for the inactive ingredients, that's absolutely true. I've had allergic reactions to some generic fluoxetine, but not others and never the brand name Prozac.
Posted by clubfitter on October 31, 2007, at 11:55:33
In reply to Re: bupropion vs. budeprion-are they different? » stargazer2, posted by Racer on October 31, 2007, at 11:51:17
What do you mean by off by 10%...also, have you had any experience with Buprpion vs. Budeprion vs. Brand Name Wellbutrin?
Posted by Racer on October 31, 2007, at 12:01:04
In reply to Re: bupropion vs. budeprion-)Racer, posted by clubfitter on October 31, 2007, at 11:55:33
> What do you mean by off by 10%...also, have you had any experience with Buprpion vs. Budeprion vs. Brand Name Wellbutrin?
Off by 10%: according to my doctor, generics can be under or over the stated dose by about that. That means that for, say, a 1 mg tablet of alprazolam, you might get .9 to 1.1 mg of the active ingredient. That's not usually a problem, unless you go from the .9 to the 1.1 when you get your next bottle. That's my doctor's story, and I trust what he tells me. (Besides, that would certainly save the generics manufacturers money on quality control.)
As for the generic Wellbutrin, no direct experience here. I take 450 mg of the Wellbutrin XL, and the generic XL is available as 300 mg. My husband, though, does take the generic. He was doing better on 150 mg of the name brand, than he is on the 300 mg of the Budeprion. Then again, if you ask me, it's the wrong drug for him anyway, since he suffers from pretty severe anxiety. From what I've seen, I'm not impressed. If they came out with a 150 or 450 mg, I'd appeal to my insurer to get the name brand.
Posted by stargazer2 on October 31, 2007, at 12:17:40
In reply to Re: bupropion vs. budeprion)stargazer, posted by clubfitter on October 31, 2007, at 9:52:43
Posted by yxibow on October 31, 2007, at 23:44:00
In reply to Re: bupropion vs. budeprion-)Racer » clubfitter, posted by Racer on October 31, 2007, at 12:01:04
It behooves to remember that brand name medications can also occasionally have quality control issues.
This is the end of the thread.
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