Psycho-Babble Medication Thread 600967

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Flonase induced depression?

Posted by sda on January 20, 2006, at 1:20:54

I started using Flonase just over a month ago for my chronic nasal congestion, but stopped using it a few days ago under the recommendation of my doctor due its inneffectiveness. I've been pretty much free of depression for several months (didn't need any antidepressants for this), but the past couple days I've been very depressed for no apparant reason (almost to the point of tears).

Just last week I was feeling confident about myself and my future, but now I feel completely dissatisfied with almost everything. Last night stayed up till 4AM questioning my entire direction in life. It just felt like everything was going wrong, and that I was completely missing out on some wonderful life that I could be having. Kind of hard to explain, but you probably get the point. I am a kind of behind schedule with my classes/homework, I've been fighting to correct my sleep schedule for a while, and I'm under a lot of pressure considerring this is my first term back at school in a year since I went on medical leave for depression. Still, I really shouldn't be in tears over things like my college major and life goals; things which I was passionate about just a week earlier.

I really hope this is due to my withdrawal from the corticosteroids in Flonase. Google searches only turned up one mention of depression as a withdrawal symptom of Flonse though. I guess I'd say I haven't felt like this since the time I tried to go off of Zoloft a bit too soon/quickly.

So has anyone else here had a comparable experience with corticosteroid withdrawal? I have a feeling that its much worse for people who are already susceptible to depression.

Sorry, I had no idea what forum to post this in.

 

Re: Flonase induced depression? » sda

Posted by vbAgent on January 20, 2006, at 16:00:19

In reply to Flonase induced depression?, posted by sda on January 20, 2006, at 1:20:54

> I started using Flonase just over a month ago for my chronic nasal congestion, but stopped using it a few days ago under the recommendation of my doctor due its inneffectiveness. I've been pretty much free of depression for several months (didn't need any antidepressants for this), but the past couple days I've been very depressed for no apparant reason (almost to the point of tears).
>
> Just last week I was feeling confident about myself and my future, but now I feel completely dissatisfied with almost everything. Last night stayed up till 4AM questioning my entire direction in life. It just felt like everything was going wrong, and that I was completely missing out on some wonderful life that I could be having. Kind of hard to explain, but you probably get the point. I am a kind of behind schedule with my classes/homework, I've been fighting to correct my sleep schedule for a while, and I'm under a lot of pressure considerring this is my first term back at school in a year since I went on medical leave for depression. Still, I really shouldn't be in tears over things like my college major and life goals; things which I was passionate about just a week earlier.
>
> I really hope this is due to my withdrawal from the corticosteroids in Flonase. Google searches only turned up one mention of depression as a withdrawal symptom of Flonse though. I guess I'd say I haven't felt like this since the time I tried to go off of Zoloft a bit too soon/quickly.
>
> So has anyone else here had a comparable experience with corticosteroid withdrawal? I have a feeling that its much worse for people who are already susceptible to depression.
>
> Sorry, I had no idea what forum to post this in.

Hi there, anything is possible. I use Nasacort AQ. I've also used a few others...To answer your question, no, I haven't experienced depression after I stopped using a corticosteroid nasal spray. Have you checked the professional prescribing reference or talked to a pharmacist? I'm sure you have. Maybe restart Zoloft...(?)...Best of luck to you.

This too will pass...Peace.

 

Re: Flonase induced depression? » vbAgent

Posted by sda on January 20, 2006, at 22:09:01

In reply to Re: Flonase induced depression? » sda, posted by vbAgent on January 20, 2006, at 16:00:19

> Hi there, anything is possible. I use Nasacort AQ. I've also used a few others...To answer your question, no, I haven't experienced depression after I stopped using a corticosteroid nasal spray. Have you checked the professional prescribing reference or talked to a pharmacist? I'm sure you have. Maybe restart Zoloft...(?)...Best of luck to you.
>
> This too will pass...Peace.

Unfortunately my sleeping has become so borked now that I've been sleeping through normal business hours. More googling did reveal more sources that comment on depression being a withdrawal side effect of corticosteroids (although I'm not positive whether they're strictly reffering to systemic drugs). Now that I look back, I did feel very aggitated and depressed when I missed three consecutive doses of Flonase over Christmas break. I didn't think much of it at the time, but now that its happened twice it kind of seems suspisious.

 

Re: Flonase induced depression? » sda

Posted by vbAgent on January 21, 2006, at 1:04:43

In reply to Re: Flonase induced depression? » vbAgent, posted by sda on January 20, 2006, at 22:09:01

> > Hi there, anything is possible. I use Nasacort AQ. I've also used a few others...To answer your question, no, I haven't experienced depression after I stopped using a corticosteroid nasal spray. Have you checked the professional prescribing reference or talked to a pharmacist? I'm sure you have. Maybe restart Zoloft...(?)...Best of luck to you.
> >
> > This too will pass...Peace.
>
> Unfortunately my sleeping has become so borked now that I've been sleeping through normal business hours. More googling did reveal more sources that comment on depression being a withdrawal side effect of corticosteroids (although I'm not positive whether they're strictly reffering to systemic drugs). Now that I look back, I did feel very aggitated and depressed when I missed three consecutive doses of Flonase over Christmas break. I didn't think much of it at the time, but now that its happened twice it kind of seems suspisious.

The good news is that if it is Flonase induced depression it should pass soon, in my opinion. Give your body time to readjust. I did find something noteworthy in a professional prescribing reference called "MPR: Monthly Prescribing Reference" under Precautions. What I gather is that depression may be a symptom if adrenal insufficiency, although I don't know for sure. (?) Ask an allergist or the doctor who prescribed it. Sorry I can't be of more help. I know you want to figure it out.

Just a guess, but if you follow your doc's directions on how to use it (not using too many sprays) and maintain a regular (nasal spray) regimen you should be fine.

Remember, take my response for what it's worth - a grain of salt. Always do your own research & such. Take care. :-)

 

Re: Flonase induced depression? » sda

Posted by yxibow on January 21, 2006, at 5:23:03

In reply to Flonase induced depression?, posted by sda on January 20, 2006, at 1:20:54


> So has anyone else here had a comparable experience with corticosteroid withdrawal? I have a feeling that its much worse for people who are already susceptible to depression.
>
> Sorry, I had no idea what forum to post this in.

It sounds more like a random spurt of winter depression than Flonase, though anything is possible. Not being oral, its route to cross the blood-brain barrier is theoretically possibly through the sinus cavity but sounds fairly rare. Yes, HPA axis depression can occur, but that is mostly associated with oral corticosteroids like Prednisolone and Dexamethasone.


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