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Dr. Bob is Robert Hsiung, MD,
[email protected]Shown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by SadDoggie on February 4, 2005, at 1:43:18
If you take an antipsychotic(blocker of dopamine) and a stimulant(releaser of dopamine), will that keep the stimulant from helping with depression? I know it obviously seems like they contradict themselves and will keep me from getting a good effect, and possibly make me feel worse since it seems I need less dopamine. But I was hoping the antipsychotic maybe worked on a different part of the brain than the stimulant so that the stimulant could still help. Anyone know about this?
SadDoggie
Posted by bart on February 4, 2005, at 11:46:55
In reply to Antipsychotic plus Amphetamine, posted by SadDoggie on February 4, 2005, at 1:43:18
anytime I tried taking one of the atypical antipsychotics (zyprexa, seroquel) with amphetamine, it just simply dampened the effect of amphetamine.
Posted by CareBear04 on February 4, 2005, at 17:00:45
In reply to Antipsychotic plus Amphetamine, posted by SadDoggie on February 4, 2005, at 1:43:18
yeah, i agree with bart. antipsychotics and other D2 antagonists inhibit the mechanism of amphetamines, especially the appetite suppressing part. as for the other way around, i haven't found any real literature documenting that.
Posted by SadDoggie on February 4, 2005, at 22:55:05
In reply to Re: Antipsychotic plus Amphetamine » SadDoggie, posted by CareBear04 on February 4, 2005, at 17:00:45
Oh, that's unfortunate :(
Posted by med_empowered on February 4, 2005, at 23:11:20
In reply to Antipsychotic plus Amphetamine, posted by SadDoggie on February 4, 2005, at 1:43:18
i used to take 15mgs abilify with my adderall, until I dropped the abilify. Basically, it reduces the effect of the stimulant in question, but the combo is still used sometimes. As for your brain "needing less dopamine," there's no research to support the "dopamine hypothesis," which holds that people with certain mental illnesses have more dopamine or are hyper-sensitive to it. It is true that all antipsychotics dampen dopamine (SIGNIFICANTLY...think 70-90%), but it is NOT supported by any research that this "corrects a chemical imbalance". Just thought I'd post that.
This is the end of the thread.
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