Psycho-Babble Medication Thread 437468

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Dextromethorphan for opiate tolerance?

Posted by jerrympls on January 3, 2005, at 22:45:33

I think I read that dextromethorphan (OTC cough suppressant) can be used for opiate tolerance....am I correct about this? Or am I mixing things up?

Re: Dextromethorphan for opiate tolerance? » jerrympls

Posted by lars1 on January 5, 2005, at 5:58:57

In reply to Dextromethorphan for opiate tolerance?, posted by jerrympls on January 3, 2005, at 22:45:33

> I think I read that dextromethorphan (OTC cough suppressant) can be used for opiate tolerance....am I correct about this? Or am I mixing things up?

There are some animal studies suggesting that this might work. Likewise for other NMDA antagonists (memantine, ketamine). I don't think there is much in the way of human studies on this subject. You could search on "dextromethorphan tolerance" on PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi) to learn more.

Lars

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