Shown: posts 1 to 3 of 3. This is the beginning of the thread.
Posted by linkadge on December 31, 2004, at 19:15:05
Of all the drugs I cannot figure out, NMDA antagonists are among the foremost.
For starters I keep reading that NMDA angagonists are notorious for causing psychosis. But lithium, has antipsychotic properties and is a potent NMDA antagonist.
The other issue refers to neuroprotection. Some sources say that NMDA antagonists are neuroprotective, but then other sources say they are neurotoxic ie:
http://www.neurotransmitter.net/nan.html
Can somebody please clarify for me what is what ??
Linkadge
Posted by jlbl2l on December 31, 2004, at 21:49:42
In reply to NMDA antagonists WHO CAN HELP ??, posted by linkadge on December 31, 2004, at 19:15:05
The drug - "Namenda" is a partial (non competative) NMDA antagonist currently under studies for so many diseases (organic and mental) that I can't even list them all. It has a good saftey profile as well. Google search or groups, or boards will provide lots of information on Namenda.
I would suggest augmentation or a trial of it for certain conditions.
It has cured or remissed people with fibromyglia according some reports.
It is currently approved for Alzhierms , recently gaining asd the #1 treatment.
As far as phsycosis or schizophrenia, I am fairly certain that genetics combined with chronic viral or bacteral infections normally in humans disrupts the brain in time causing these things.
I know considerable information on NMDA, GABA, DOPAMINE and NOREP connections in the brain and suspected disorder causes. babblemail or respond and i will try to answer 1 question @ a time.
Hope this helps.
jlbl2l
Posted by ed_uk on January 1, 2005, at 11:32:20
In reply to NMDA antagonists WHO CAN HELP ??, posted by linkadge on December 31, 2004, at 19:15:05
Hi Link,
I imagine it depends very much on dose. Look at dextromethorphan (DXM) for example, at low cough-supressant doses it's generally well-tolerated with few side effects... but if you drink the bottle you're in for a shock.
See... http://www.erowid.org/chemicals/dxm/dxm.shtml
Read the 'Experiences'
Ed.
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