![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
[email protected]Shown: posts 2 to 26 of 26. Go back in thread:
Posted by cubbybear on November 20, 2004, at 7:00:55
In reply to Rare psychotropics, posted by ed_uk on November 19, 2004, at 13:31:16
? Have you ever taken any psychiatric drugs that are not on the market in the US? What country do you live in? What was your experience?
>
> I've taken Moclobemide, a reversible MAOI anti-depressant that isn't available in the U.S. but available in many other nations of the world. I live in Bangkok. My experience with this drug was awful--it made my depression worse.
Posted by SLS on November 20, 2004, at 9:20:31
In reply to Re: Rare psychotropics » ed_uk, posted by cubbybear on November 20, 2004, at 7:00:55
> ? Have you ever taken any psychiatric drugs that are not on the market in the US? What country do you live in? What was your experience?
> >
> > I've taken Moclobemide, a reversible MAOI anti-depressant that isn't available in the U.S. but available in many other nations of the world. I live in Bangkok. My experience with this drug was awful--it made my depression worse.I had a similar experience with moclobemide. It made my depression dramatically worse. I was immobilized by it. I spent all day lying on the couch curled up in the fetal position and wimpering. It was horrific.
- Scott
Posted by Iansf on November 20, 2004, at 13:21:50
In reply to Rare psychotropics, posted by ed_uk on November 19, 2004, at 13:31:16
>
> Amineptine
> Brofaromine
> Butriptyline
> Captodiame
> Carpipramine
> Dibenzepin
> Etoperidone
> Iproniazid
> Lofepramine (popular in UK)
> Medifoxamine
> Melitracen
> Milnacipran
> Minaprine
> Nialamide
> Opipramol
> oxypertine
> Pirlindole
> Quinupramine
> Rolipram
> Tianeptine
> Tofisopam
> Toloxatone
> valnoctamide
> Viloxazine
>
>
I had no idea there were so many drugs I'd never heard of, though as it happens I have tried three that are on the list.Tianeptine and minaprine for me were both like taking a placebo - no positive effects, no negative effects, no side effects.
Viloxazine made my depression worse. Perhaps if I had stuck with it more than three weeks, the negative effect would have reversed, but I was becoming so deeply depressed I didn't dare continue.
John Mc
Posted by ed_uk on November 20, 2004, at 14:37:25
In reply to Re: Rare psychotropics » ed_uk, posted by Iansf on November 20, 2004, at 13:21:50
Hi...
I've also taken moclobemide. No side effects, no good effects, no withdrawal symptoms. Felt a bit like a sugar pill!
Ed
PS. John MC... There are lots of other drugs I could have put on the list as well but I didn't have time!! It's amazing how there are so many drugs in other parts of the world that hardly anyone knows about.
Posted by cubbybear on November 21, 2004, at 4:56:56
In reply to Re: Rare psychotropics » ed_uk, posted by SLS on November 20, 2004, at 9:20:31
> > > I've taken Moclobemide, a reversible MAOI anti-depressant that isn't available in the U.S. but available in many other nations of the world. I live in Bangkok. My experience with this drug was awful--it made my depression worse.
>
> I had a similar experience with moclobemide. It made my depression dramatically worse. I was immobilized by it. I spent all day lying on the couch curled up in the fetal position and wimpering. It was horrific.
>
>
> - ScottHi Scott,
I know that I'm going off the orginal thread but I've always been curious about this. If I recall, you have responded well to Parnate or Nardil, correct? I wonder if there's any correlation or pattern, that people who have (previously) done well on an irreversible MAOI, do very badly on the reversible ones like Moclobemide. Any ideas?
cubbybear
>
>
Posted by SLS on November 21, 2004, at 7:01:21
In reply to Re: Rare psychotropics » SLS, posted by cubbybear on November 21, 2004, at 4:56:56
> > > > I've taken Moclobemide, a reversible MAOI anti-depressant that isn't available in the U.S. but available in many other nations of the world. I live in Bangkok. My experience with this drug was awful--it made my depression worse.
> >
> > I had a similar experience with moclobemide. It made my depression dramatically worse. I was immobilized by it. I spent all day lying on the couch curled up in the fetal position and wimpering. It was horrific.
> >
> >
> > - Scott
>
> Hi Scott,
> I know that I'm going off the orginal thread but I've always been curious about this. If I recall, you have responded well to Parnate or Nardil, correct? I wonder if there's any correlation or pattern, that people who have (previously) done well on an irreversible MAOI, do very badly on the reversible ones like Moclobemide. Any ideas?
> cubbybearYes, I have done better on Parnate and Nardil than I have on most other drugs. Off hand, I can't think of any reason why response to the irreversibles would be an index of exacerbation by the reversibles. I have, however, run across a Medline abstract that reports moclobemide reducing the dopamine content of an area of the brain that I can't remember. My guess is that this is the mechanism by which it exacerbates depression in some people.
How are you doing?
- Scott
Posted by ed_uk on November 21, 2004, at 11:15:45
In reply to Re: Rare psychotropics » SLS » cubbybear, posted by SLS on November 21, 2004, at 7:01:21
Hey, I just found a massive list of psychotropic drugs on Peter Lehmann's site. I haven't made any attempt to check the accuracy of the list so don't blame me if there are mistakes!!!! I just did a cut and paste, that's all. I did notice some bizarre errors in his list of neuroleptics so I didn't copy it.
Here is the place to find drugs that you've never been on! Some of them are available in distant countries, some are not on the market at all.
Does anyone have any personal experience of any of the more unusual drugs on these lists?
Antidepressants, common and rare....
Ademetionine
Amfebutamone
Amiflamine
Amineptine
Amitriptyline
Amitriptylinoxide
Amoxapine
Befloxaton
Benmoxin
Bupropion
Butriptyline
Caroxazone
Carpipramine
Cianopramine
Cidoxepin
Ciclazindol
Cimoxatone
Citalopram
Clomacran
Clomipramine
Clovoxamine
Dapoxetine
Demexiptiline
Desipramine
Dibenzepin
Dihydroergosine
Dimetacrine
Dosulepin
Dothiepin
Doxepin
Duloxetine
Echinopsidine iodide
Escitalopram
Etryptamine
Femoxetine
Fengabine
Fenoxypropazine
Flerobuterol
Flesinoxan
Flibanserin
Fluoxetine
Fluparoxan
Fluvoxamine
Gepirone
Idalpine
Idazoxan
Ifoxetine
Igmesine
Iprindole
Iproclozide
Iproniazid
Imipramine
Incazane
Iprindole
Ipsapirone
Isocarboxazid
Levoprotiline
Lofepramine
Maprotiline
Mebanazine
Medifoxamine
Melitracen
Metapramine
Metfendrazine
Metralindole
Mianserin
Milnacipran
Minaprine
Mirtazapine
Moclobemide
Napactadine
Napamezole
Nefazodone
Nialamide
Nisoxetine
Nitroxazepine
Nomifensine
Nortriptyline
Noxiptyline
Opipramol
Oxaflozane
Oxitriptan
Pargyline
Paroxetine
Phenelzine
Pheniprazine
Phenoxypropazine
Pipofenine
Pirlindole
Pivhydrazine
Propizepine
Protriptyline
Quinupramine
Racoxitriptan
Reboxetine
Rolipram
Safrazine
Seproxetine
Sertraline
Setiptiline
Tandamine
Tandospirone
Teniloxazine
Tetrindole
Tianeptine
Tofenacin
Toloxatone
Tomoxetine
Tranylcypromine
Trazodone
Trimipramine
Trocimine
Tryptophan
Venlafaxine
Viloxazine
Zimeldine
Zometapine
Sedatives, hypnotics and anxiolytics,
Both common and rare are listed.........Abecarnil
Adinazolam
Alpidem
Alprazolam
Azaperon
Benactyzine
Bentazepam
Benzodiazepinectamine
Bretazenil
Bromazepam
Brotizolam
Buspirone
Camazepam
Captodiame
Centalun
Cetamolol
Chlordemetildiazepam
Chlordiazepoxide
Chlormezanone
Cinolazepam
Clobazam
Clonazepam
Clorazepate Dipotassium
Clorazepate Potassium
Clotiazepam
Cloxazolam
Delorazepam
Demetildiazepam
Demoxepam
Diazepam
D,L-Kavain
Doxefazepam
Epanolol
Estazolam
Ethyl Loflazepate
Etifoxine
Etizolam
Etoperidone
Febabarmate
Fenpentadiol
Fludiazepam
Flumetazepam
Flunitrazepam
Flurazepam
Flutazolam
Flutoprazepam
Glaziovine
Halazepam
Haloxaloam
Hydroxyzine
Ipsaspirone
Kawain
Ketazolam
Loprodiol
Loprazolam
Lorazepam
Lorazepam pivalate
Lormetazepam
Mebutamate
Meclozine
Medazepam
Medazepam dibudinate
Mefequizone
Menilon
Mepiprazole
Meprobamate
Metaclazepam
Methylpentynol
Mexazolam
Midazolam
Nimetazepam
Nitrazepam
Nordazepam
Oxanamide
Oxazepam
Oxazepam hemisuccinate
Oxazolam
Perlapine
Phenaglycodol
Pinazepam
Prazepam
Quazepam
Reclazepam
Ritanserin
Soquinolol
Suriclone
Temazepam
Tetrabamate
Tetrazepam
Tilisolol
Tofisopam
Triflubazam
Triazolam
Trimetozine
Tybamate
Zaleplon
Zalospiron
Zolazepam
Zolpidem
Zopiclone
Ed
Posted by ed_uk on November 21, 2004, at 11:40:50
In reply to Re: More rare psychotropics, posted by ed_uk on November 21, 2004, at 11:15:45
HI
If anyone wants to find out more about any of the drugs that I listed go to...
www.psychotropics.dk
.........and then go to the alphabetical index and click on the drug that you are interested in. The info is useful but there are some mistakes, so take care!Ed
Posted by darkhorse on November 22, 2004, at 7:51:20
In reply to Re: More rare psychotropics, posted by ed_uk on November 21, 2004, at 11:15:45
Hi,
This is my list :
>
> Antidepressants, common and rare....
>
>
> Amineptine
> Amitriptyline
> Bupropion
> Citalopram
> Clomipramine
> Desipramine
> Dibenzepin
> Dosulepin
> Dothiepin
> Doxepin
> Escitalopram
> Fluoxetin
> Fluvoxamine
> Imipramine
> Maprotiline
> Melitracen
> Mianserin
> Milnacipran
> Mirtazapine
> Moclobemide
> Nefazodone
> Nortriptyline
> Opipramol
> Paroxetine
> Protriptyline
> Reboxetine
> Sertraline
> Setiptiline
> Tianeptine
> Tranylcypromine
> Trazodone
> Venlafaxine
> Viloxazine>
>
> Sedatives, hypnotics and anxiolytics,
> Both common and rare are listed.........> Alprazolam
> Bentazepam
> Bromazepam
> Brotizolam
> Buspirone
> Chlordemetildiazepam
> Chlordiazepoxide
> Cinolazepam
> Clobazam
> Clonazepam
> Clorazepate Dipotassium
> Clorazepate Potassium
> Cloxazolam
> Delorazepam
> Diazepam
> Estazolm
> Flunitrazepam
> Hydroxyzine
> Ketazolam
> Lorazepam
> Lormetazepam
> Meprobamate
> Midazolm
> Nitrazepam
> Oxazepam
Phenobarbital
> Prazepam
> Tetrazepam
> Tofisopam
> Triazolam
> Zolpidem
> Zopiclone
>
>
Any questions?? apart from being a great guinea pig!!!
Adam
>
>
Posted by cubbybear on November 22, 2004, at 9:00:15
In reply to Re: Rare psychotropics » SLS » cubbybear, posted by SLS on November 21, 2004, at 7:01:21
I have, however, run across a Medline abstract that reports moclobemide reducing the dopamine content of an area of the brain that I can't remember. My guess is that this is the mechanism by which it exacerbates depression in some people.
>
> How are you doing?
>
>
> - ScottHave been feeling pretty good mentally, as long as I get my daily 30 mg. of Parnate,every day. This year marks 20 years that I've been taking it. As you may remember from my previous posts, I now have to deal with the prospect of going for a colonoscopy and have been doing plenty of website research regarding safe anaesthesia/sedation with Parnate for this procedure.
Posted by ed_uk on November 22, 2004, at 11:18:51
In reply to Re: More rare psychotropics, posted by darkhorse on November 22, 2004, at 7:51:20
Hi Adam,
Yes, I have many questions! Too many, so I'll just ask a few so you're not overwhelmed!
What was your experience with amineptine? How did it differ from a stimulant?
What was melitracen like?
What was your experience with opipramol?
How did you find tranylcypromine?
How did protriptyline compare with desipramine?
Did hydroxyzine relieve your anxiety any better than other sedating antihistamines?
How did you find meprobamate and phenobarbital?
Apart from clobazam, did any of the benzos stand out as being especially bad?
Thank you!
Ed
Posted by pablo1 on November 23, 2004, at 17:37:55
In reply to Re: More rare psychotropics, posted by ed_uk on November 22, 2004, at 11:18:51
>
> What was your experience with amineptine? How did it differ from a stimulant?
It has more of a happy factor and less of a concentration effect. More druggy & euphoric but not that strong the way ritalin can be quite potent at a little higher dose, ameneptine doesn't make a huge difference at higher doses. Ameneptine was quite motivating for me and definitely relieved depression, ritalin just makes me zone in on things & not necessarily all that happy or more pleasure in life.
Posted by pablo1 on November 23, 2004, at 17:51:58
In reply to Re: More rare psychotropics, posted by ed_uk on November 21, 2004, at 11:40:50
Phenibut is one listed on that web site though not much info. Dr. Bob might be tempted to move this to the Alternative forum but I assure you it is a powerful psychoactive pharmeceutical.
It works on GABA maybe vaguely like GHB & is currently available legally over the internet. It has been around in Russia since the 1960's used for various psychiatric & medical uses. Mostly it's good for anti-anxiety & mood lifting type action. It does get you high at larger doses & apparently tolerance builds rather quickly. It lasts a long time like 18 hours and can take up to 2 hours before you feel the effects. I've just got some & been trying it for a few days to replace 1mg klonopin very effectively at 1/2 gram dose. I tried 1-1/2g yesterday evening & woke in the middle of the night with very detailed vivid dreams. People are reporting all sorts of different reactions but most agree it's definitely very psychoactive. I can't find much that isn't about using it recreationally, that's why I thought I'd mention it here. I guess it's just recently been 'discovered' in the US & there isn't much experience. I expect it will become controlled at some time.
Posted by Iansf on November 23, 2004, at 20:07:53
In reply to Re: ameneptine vs stimulant » ed_uk, posted by pablo1 on November 23, 2004, at 17:37:55
> It has more of a happy factor and less of a concentration effect. More druggy & euphoric but not that strong the way ritalin can be quite potent at a little higher dose, ameneptine doesn't make a huge difference at higher doses. Ameneptine was quite motivating for me and definitely relieved depression, ritalin just makes me zone in on things & not necessarily all that happy or more pleasure in life.>
Why did you stop taking amineptine? Because of the ban or for other reasons?
Posted by Iansf on November 23, 2004, at 20:16:21
In reply to Re: Phenibut » ed_uk, posted by pablo1 on November 23, 2004, at 17:51:58
Here's a link with a good discussion of phenibut:
http://www.1fast400.com/i64_Phenibut.html
Posted by darkhorse on November 24, 2004, at 6:20:10
In reply to Re: More rare psychotropics, posted by ed_uk on November 22, 2004, at 11:18:51
Hello ED :
> Hi Adam,
>
> Yes, I have many questions! Too many, so I'll just ask a few so you're not overwhelmed!
>
> What was your experience with amineptine? How did it differ from a stimulant?Amineptine at 200mg caused more and immediate depression.At 800=mg it acted like a stimulant,not an AD.
>
> What was melitracen like?I took it in a combo Deanxit which had flupenthixol...clean drug with no severe side effects but no effects at all.
>
> What was your experience with opipramol?That is a very good one..I only found it in the Sudan and seems to have vanished from planet earth...it has an immediate anxiolytic effects not unlike maprotiline.
>
> How did you find tranylcypromine?Took it at 60mg aday with diet.restrictions. stopped it after about a month because it made me behave like I was drunk and everybody noticed + itmade me eat like a horse and gained a lot of weight (it is not weight neutral at all !!).
>
> How did protriptyline compare with desipramine?Surprisingly,desipramine was more stimulating and caused tachycardia,while proto I took with fluoxetine but did not deliver the goods(motivation..etc),only more increase in weight (Again prot is NOT weight neutral)..I also hated reboxetine..the only pure NE that was really good for me was Ludiomil,and to a lesser extent Nortriptyline.
>
> Did hydroxyzine relieve your anxiety any better than other sedating antihistamines?It was like a placebo...nothing!
>
> How did you find meprobamate and phenobarbital?Meprobamate was very very heavy sedating and immediatly made me depressed...but phenobarbital was really good but I kept escalating the dose to get more benefit,so I stopped for fear of dependence....
Anothrer drug that gave me a very good anxiolytic effect and a nice buzz was chlormethiazole..do you have it in UK?
>
> Apart from clobazam, did any of the benzos stand out as being especially bad?Worst benzos : Cinloazepam,Clobazam,Clonazepam,Clorazepate,Tetrazepam.
Very good but rare benzos :
Bentazepam,Delorazepam,Cloxazolam,Flunitrazepam,Tofisopam.Very good benzos and more common :
Bromazepam,Lorazepam,Alprazolam.
>
> Thank you!
Adam
>
>
Posted by ed_uk on November 24, 2004, at 9:11:10
In reply to Re: More rare psychotropics, posted by darkhorse on November 24, 2004, at 6:20:10
Hi!
Thank you for the information, it was very interesting.
How did maprotiline differ from other NE reuptake inhibitors?
RE. Opipramol. Here is some info on the availability of opipramol. I have no idea whether it is accurate or up to date. I suspect that it is neither! Names of countries are abbreviated. As you can see, some preparations have been deleted and are no long available.
Commercial Info.
Depenil Terra........ TK: tabs.50mgEnsidon Ciba Geigy.......... SWE(deleted), USA: s-c tabs. 50mg
Insidon Novartis........... A, BRD, NL, GR, CH, ITA, F, B (deleted), ICL(deleted), DK(deleted), TK, Ciba-Geigy, DK, FIN (deleted), CZ, PL, Ciba-Geigy/Novartis, LTV, Geigy, NOR (deleted), EIRE: s-c. tabs. 50mg
Insomin Abdi Ibrahim........ TK: s-c tabs.50mg
Inzeton Biokem.............. TK: tabs.50mg
Opridon Deva............ TK: f-c tabs.50mg
Oprimol Fako........... TK: s-c tabs.50mg
Pramolan Polpharma.......... PL: s-c tabs.50mg
....... The current edition of Martindale suggests than opipramol may still be available in Austria, Germany, Israel and Switzerland. I have no idea if this info is up to date. Apparantly, Opipramol is no longer used in Belgium, France, Ireland, Italy, Netherlands, Norway or Sweden.Was opipramol anxiolytic after a single dose? What were the side effects like?
When you say Parnate made you act like you were drunk do you mean it made you over confident and disinhibited? Sounds like a good treatment for SP!!
How did reboxetine compare to TCAs like desipramine?
Yes, we do have chlormethiazole in the UK. We call it Heminevrin. It's only used to help people withdraw from alcohol though! No one uses it as an anxiolytic.
I find it very silly that some countries seem to think that flunitrazepam (Rohypnol) is so much more dangerous than other benzos. All the major benzos can cause amnesia, sedation, disinhibition, aggression etc. Flunitrazepam is not unique!
All the best,
Ed.
Posted by ed_uk on November 24, 2004, at 9:43:18
In reply to Re: More rare psychotropics » darkhorse, posted by ed_uk on November 24, 2004, at 9:11:10
Hi!
Thank you pablol for the information.
Anyone else taken any unusual meds?Regards,
Ed.
Posted by pablo1 on November 24, 2004, at 11:56:53
In reply to Re: ameneptine vs stimulant » pablo1, posted by Iansf on November 23, 2004, at 20:07:53
It is expensive ordered online & impractical. It is still available in South America. I ordered indirectly from there at high markup.
Also I was able to get the ritalin so thought I'd try that instead since I could continue that if it works.
I was also taking amisulpride with the ameneptine & maybe liked that better. Ameneptine is supposed to have tolerance issues & some liver damage though I'm not clear how serious that is.
>
> Why did you stop taking amineptine? Because of the ban or for other reasons?
>
>
Posted by darkhorse on November 25, 2004, at 6:54:18
In reply to Re: More rare psychotropics » darkhorse, posted by ed_uk on November 24, 2004, at 9:11:10
> Hi!
>
>
>
> How did maprotiline differ from other NE reuptake inhibitors?It gave a fast calming feeling very different than SSRIs.It did not give me this indifference/apthy feeling...it killed anxiety and made me focus,but not that energetic or sociable,just calm and focused.Also no tremors or tachycardia like other NEs..I think it has a moderate anti histaminic,anti sertonergic effects which relieves insomnia and anxiety + the NE inhibition which gives the antidepressant and focused effects.
I think it is way underrated and this thing about having seizures above 150mg is overexaggerated and the same could be said about both clomipramine and bupropion(I only took 75mg and never needed more anyway!).....but I still think that Imipramine gave me better antidepressant/motivated effects but less anxiolytic effects than maprotiline,oh and AC effects on maprotiline are benign.
(I think Maprotiline ranks for me among the top -available- ADs along with imipramine,fluoxetine)
>
>
> ....... The current edition of Martindale suggests than opipramol may still be available in Austria, Germany, Israel and Switzerland.It is not available in Austria.I only found it in the Sudan in 1995 (Insidon).
>
> Was opipramol anxiolytic after a single dose? What were the side effects like?Yes.some sedation,same degree as maprotiline,not like amitriptyline,doxepin or dothiepin.
>
> When you say Parnate made you act like you were drunk do you mean it made you over confident and disinhibited? Sounds like a good treatment for SP!!If being disinhibited and overconfident and arrogant and unsympathetic is the opposite to SP,I do not want it...my personality changed with this medication and I felt I'm not the same.but,again,with something like bromazepam and xanax you really erase SP without erasing who you are.
>
> How did reboxetine compare to TCAs like desipramine?Oooooh ! this one was a terrible experience,within 48 hours I had SEVERE constipation and urinatry problems and within days I had severe depression with horrible ideas,I couldn't even smile..if there is a depression pill it is this one...I tried it again with as little as 1mg with fluoxetine,but it was too much and killed prozac's effects...
I"m sure there is something in the chemestry of this medication that makes it unlike desipramine and the other NEs,maybe an NE2 antagonist effect...I noticed from older posts people had very bad reactions too...I swear if you give reboxetine to a normal guy but sensetive to it like me and others for a week or 2 I'm sure he will commit suicide.
>
> I find it very silly that some countries seem to think that flunitrazepam (Rohypnol) is so much more dangerous than other benzos. All the major benzos can cause amnesia, sedation, disinhibition, aggression etc. Flunitrazepam is not unique!I could not agree more !
>
> All the best,Adam.
Posted by ed_uk on November 25, 2004, at 8:14:40
In reply to Re: More rare psychotropics, posted by darkhorse on November 25, 2004, at 6:54:18
Hi Adam,
Thank you for answering my questions.
Yes, there does seem to be something strange about reboxetine. I wonder what makes it so horrible!
You made tranylcypromine sound scary! Do you think it made you manic? Have you ever been on any other MAOIs.... phenelzine, isocarboxazid etc.
I think opipramol was originally a German drug. Perhaps it's still available there.
How did the sedation from maprotiline differ from amitriptyline and dothiepin?
It's funny how when meprobamate was introduced it was claimed to be a 'selective' anxiolytic... unlike the barbiturates. But you prefered phenobarbital, finding it less sedating! I guess we're told that all new anti-anxiety drugs are selective when they're first introduced.
All the best...
Ed.PS. Darkhorse is a cool name.
Posted by SLS on November 25, 2004, at 8:32:21
In reply to Re: More rare psychotropics » darkhorse, posted by ed_uk on November 25, 2004, at 8:14:40
Me too.
> > > How did reboxetine compare to TCAs like desipramine?
> > Oooooh ! this one was a terrible experience,within 48 hours I had SEVERE constipation and urinatry problems and within days I had severe depression with horrible ideas,I couldn't even smile..if there is a depression pill it is this one...I tried it again with as little as 1mg with fluoxetine,but it was too much and killed prozac's effects...
> > I'm sure there is something in the chemestry of this medication that makes it unlike desipramine and the other NEs,maybe an NE2 antagonist effect...I noticed from older posts people had very bad reactions too...I swear if you give reboxetine to a normal guy but sensetive to it like me and others for a week or 2 I'm sure he will commit suicide.
> Yes, there does seem to be something strange about reboxetine. I wonder what makes it so horrible!
My experience with reboxetine was horrific. It exacerbated my depression and propelled me into a suicidal state for the entire time I took it. I aborted the trial after two weeks. Within 36 hours of its discontinuation, I gratefully returned to baseline. I experienced a great deal of anxiety with reboxetine, which was contributory to suicidality.
- Scott
Posted by darkhorse on November 25, 2004, at 9:11:04
In reply to Re: More rare psychotropics » darkhorse, posted by ed_uk on November 25, 2004, at 8:14:40
> Hi Ed
>
> You made tranylcypromine sound scary! Do you think it made you manic? Have you ever been on any other MAOIs.... phenelzine, isocarboxazid etc.No I wasn't manic,maybe hypomanic..well I do not want to label things,but what I'm sure of is that I was not myself and realised it(and others too)..
I don't want to scare you,people are different...but I'm not going to put Parnate in my mouth again..I want to be ME!!...
I tried selegiline 5mg in the morning all by itself and for 1st week I felt it was what I was looking for ; it gave me energy motivation and a nice stimulation. only side effect was sweating...but, unfortunatly after a week or more it "pooped-out" and started to make me feel tired and sleepy?!!...
the last MAO I tried was Moclobemide at 150-300mg it did NOTHING at 450-600mg it made one effect :increase in weight so it was a total waste of money and a failure.
>>
> How did the sedation from maprotiline differ from amitriptyline and dothiepin?VERY different,if Amitrip sedation was 10,dothiepin would be 7-8 ,maprotiline would be like 4-5...
You see, Maprotiline's sedation dose not interfere with life like amitriptyline or the severely sedating doxepin and mirtazapine,it is more in the category of "benzo" sedation (at 25-75mg)
>
> It's funny how when meprobamate was introduced it was claimed to be a 'selective' anxiolytic... unlike the barbiturates. But you prefered phenobarbital, finding it less sedating! I guess we're told that all new anti-anxiety drugs are selective when they're first introduced.Haha!! That is very true !
>
> All the best...
> Ed.
>
> PS. Darkhorse is a cool name.Thank YOU for your kindness .
Adam.
P.S. Have you also tried the dreaded rebox?...
Posted by darkhorse on November 25, 2004, at 9:13:50
In reply to Re: More rare psychotropics, posted by SLS on November 25, 2004, at 8:32:21
>Hello Scott
Thank you for sharing your experience....it is good to find that we are not alone !
Adam.
Me too.
>
> > > > How did reboxetine compare to TCAs like desipramine?
>
> > > Oooooh ! this one was a terrible experience,within 48 hours I had SEVERE constipation and urinatry problems and within days I had severe depression with horrible ideas,I couldn't even smile..if there is a depression pill it is this one...I tried it again with as little as 1mg with fluoxetine,but it was too much and killed prozac's effects...
>
> > > I'm sure there is something in the chemestry of this medication that makes it unlike desipramine and the other NEs,maybe an NE2 antagonist effect...I noticed from older posts people had very bad reactions too...I swear if you give reboxetine to a normal guy but sensetive to it like me and others for a week or 2 I'm sure he will commit suicide.
>
> > Yes, there does seem to be something strange about reboxetine. I wonder what makes it so horrible!
>
> My experience with reboxetine was horrific. It exacerbated my depression and propelled me into a suicidal state for the entire time I took it. I aborted the trial after two weeks. Within 36 hours of its discontinuation, I gratefully returned to baseline. I experienced a great deal of anxiety with reboxetine, which was contributory to suicidality.
>
>
> - Scott
>
>
Posted by ed_uk on November 25, 2004, at 12:46:59
In reply to Re: More rare psychotropics, posted by darkhorse on November 25, 2004, at 9:13:50
Hi Adam,
No, I've never taken the dreaded reboxetine. I think I'll stick with lofepramine. I can't imagine reboxetine having any major advantages over lofep for me. Anyway, no one ever prescribes Edronax in England. I've worked in various pharmacies and I've never once seen a prescription for it!
Ed.
This is the end of the thread.
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