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Dr. Bob is Robert Hsiung, MD,
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Posted by blnch on October 30, 2004, at 18:15:03
In reply to Re: Cymbalta Side-effects/Nausea, etc. ?s, posted by banga on October 30, 2004, at 16:38:48
I do want to report that I found someone here advising crystallized ginger for nausea. I got some yesterday and it does provide some relief. I think less is more. YMMV.
Posted by ed_uk on October 30, 2004, at 18:25:05
In reply to Re: Cymbalta Side-effects/Nausea, etc. ?s, posted by blnch on October 30, 2004, at 18:15:03
Hello.......
The most effective and well tolerated antidepressant for me has been lofepramine (Gamanil). It is one of the most popular TCAs in the UK. Nausea is very rare with lofepramine and its anticholinergic side effects are milder than any of the other TCAs. It is not on the market in the US (do you live there?) but your pharmacy may be able to import it if your doctor was willing to prescribe it.
Ed
Posted by blnch on October 30, 2004, at 18:32:29
In reply to Re: Cymbalta Side-effects/Nausea, etc. ?s, posted by ed_uk on October 30, 2004, at 18:25:05
Thank you. I am not aware that this med is available in the US - yes, I am across the pond from you. I will look into it.
Posted by ed_uk on October 30, 2004, at 19:20:19
In reply to Re: Cymbalta Side-effects/Nausea, etc. ?s » ed_uk, posted by blnch on October 30, 2004, at 18:32:29
Lofepramine is an old drug (I think it was first tested as an antidepressant in about 1975 if I remember correctly). Its always been quite popular in the UK, especially before the SSRIs were introduced. I imagine you could get hold of it fairly easily, it's available in lots of other places as well as the UK.
Ed
Posted by CrazyCO on October 30, 2004, at 21:40:08
In reply to Re: Cymbalta Side-effects/Nausea, etc. ?s, posted by blnch on October 30, 2004, at 12:37:28
I take cymbalta currently 120mg and I have had slight nausea about 30 minutes or so after I take it. But it is more like butterflies than actual nauea and it passes very quickly.
Posted by CrazyCO on October 30, 2004, at 21:41:40
In reply to Re: Cymbalta Side-effects/Nausea, etc. ?s, posted by blnch on October 30, 2004, at 12:37:28
Seroquel has not given many any food craving thus far, and I hope it stays that way, I've only been taking it for about 2 weeks now for sleep.
Posted by ravenstorm on October 31, 2004, at 10:41:51
In reply to Re: Cymbalta Side-effects/Nausea, etc. ?s » blnch, posted by CrazyCO on October 30, 2004, at 21:41:40
blnch--what happened to you when you tried parnate?
For those who posted about gamanil:what are the usual side effects?
Posted by blnch on October 31, 2004, at 12:41:22
In reply to Re: Cymbalta Side-effects/Nausea, etc. ?s » blnch, posted by CrazyCO on October 30, 2004, at 21:41:40
Thanx, CrazyCO, for your comments on both Cymbalta re: "nausea"(butterflies) and on Seroquel re: (no) food cravings - so far - for you. MUCH appreciated - gives me some hope and, boy, do I need it!
Posted by blnch on October 31, 2004, at 12:58:49
In reply to Re: Cymbalta Side-effects/Nausea, etc. ?s, posted by ravenstorm on October 31, 2004, at 10:41:51
ravenstorm: I went into the Parnate "experience" quite determinedly. As per my usual, I tried the lowest dose. Within 5 days, I was driving, not caring if I had a wreck. (This was markedly different from the wishful thinking/ slight urge to have a head-on wreck that I fairly often have with plain ole suicidal ideation. Fortunately for all, I have LOTS of impulse control.)
Other Parnate pleasantries included the usual nausea - even worse than my before #1 worst, Wellbutrin. Wellbutrin seems to be an odd AD: many do so well on it, but for those of us who don't, we do REALLY badly on it - we just despise it! Anxiety on Parnate was like Wellbutrin x 3. I am one who can hande ALOT of caffeine, but Parnate was like someone had poured 3 pots of coffee down my throat. This was last February, and it's still that vividly horrible in my memory.
Posted by happy lady on November 1, 2004, at 12:52:35
In reply to Re: Cymbalta Side-effects/Nausea, etc. ?s, posted by blnch on October 31, 2004, at 12:41:22
Hi there Sarah,
I have been taking cymbalta at 30 mgs for 38 days. I have noticed a great increase in mood and anxiety. however, I am experiecing some GI effects. I have nausea off and on. I have needed to up my protonix as I have an increase in GERD symptons. I will see my doctor tomorrow with the hope of maintaining cymbalta. Since I have been on cymbalta for 38 days I doubt the nausea will diminish. I also take 40 mgs of of paxil. Sometimes the combining of theses meds cause to much serontin to be dumped into the stomach producing nausea. Maybe my doctor will lower the paxil. The best to all of you. Keep trying.
Happylady
Posted by blnch on November 1, 2004, at 15:04:08
In reply to Re: Cymbalta Side-effects/Nausea, etc. ?s, posted by happy lady on November 1, 2004, at 12:52:35
Thank You! Sounds like we have much in common, unfortunately...lol.
I absolutely agree with you that serotonin is the culprit re: nausea. For me, any serotonin whatsoever is like dropping a bomb down my esophagus/ GI tract. Like you, the nausea side-effect does NOT go away (at least, not for far too many years, now.)
FYI: I just lowered my Prevacid from 2 of the stonger ones to 1 a day. My GP had OKed my taking twice what is recommended because, as you may well know, these proton pump meds often do NOT work for the promoted 24 hrs. However, I finally solved yet another BIG medical mystery: it was the AM Prevacid dose that was actually making my nausea (not GERD) worse, taken along with Prozac or (fill in the blank of the other meds I've tried). Wish I had figured this out before two more years were gone from my life! Of course - dare I say it? - one would think that's the job of the "learned" GP or pdoc.
If I do end up using Cymbalta, I will be using it as a stand-alone med (dropping the Prozac.) Maybe, then, one Prevacid a day will hold me(?)
It IS distressing to hear you have increased GERD with Cymbalta, but I REALLY appreciate the heads up. AND, that also ties in with someone's speculation here that Cymbalta is like a "cleaned up" Nortrip.(Pamelor). Hmmm.
Posted by sunshine211 on November 2, 2004, at 0:00:27
In reply to Cymbalta Side-effects/Nausea, etc. ?s, posted by blnch on October 29, 2004, at 4:12:09
1.I don't have any nausea and haven't since I started taking it a month and a half ago.
2.I do have constipation! Agghhh! But I have been adding a high fiber cereal to my regular breakfast (it's low fat too). It has been getting better.
3.I sleep better now than I have in months. I take half of a .05mg of Klonopin at night with the Cymbalta.
I took paxil before, my mood is way better now (knock on wood).
Posted by sunshine211 on November 2, 2004, at 0:05:20
In reply to Re: Cymbalta Side-effects/Nausea, etc. ?s, posted by blnch on October 29, 2004, at 17:20:28
My brother takes seroquel for sleep. It is the only thing he can take becasue of substance abuse problems. BE CAREFUL. He gets really dazed out and then knocks out for the night. He had the runs for a while but his bodu adjusted. It's pretty strong stuff.
Posted by shiz on November 2, 2004, at 9:01:00
In reply to Re: Cymbalta+seroquel, posted by sunshine211 on November 2, 2004, at 0:05:20
has anybody quit taken cymbalta yet and get and side effects coming off? or not?
Posted by ravenstorm on November 2, 2004, at 13:21:14
In reply to Re: Cymbalta+seroquel, posted by shiz on November 2, 2004, at 9:01:00
Blnch, please let us know what you decide to do. I have horrible GERD like you . I wish so badly that I could at least tolerate prozac, but I can't even take that. Wellbutrin became intolerable to me due to anxiety, so hearing that you couldn't hack the parnate either makes me reluctant to try that next and I really am not a fan of the side effects I'm hearing about with Nardil.
I just don't think I'm going to take anything with noreph. in it, so I'm reluctant to try the cymbalta (That and the severe nausea that I know would accompany it).
Please do keeps us updated if you decide to try the cymbalta.
Posted by blnch on November 2, 2004, at 14:31:25
In reply to Re: Cymbalta+seroquel, posted by sunshine211 on November 2, 2004, at 0:05:20
Thanx for the heads up on the Seroquel! I, too, had a "substance abuse problem." In my case, it was 100% self-medicating my intractible Major Depression. Cocaine, then, crack was my drug of choice. I just celebrated 7 years clean, as the jargon goes.
Posted by blnch on November 2, 2004, at 14:49:05
In reply to Re: Cymbalta+seroquel, posted by ravenstorm on November 2, 2004, at 13:21:14
Tomorrow I will find out "what it's gonna be." Nervous as a cat starting yesterday, as I am now not so sure I'm willing to go thru "all this" YET again. The GERD factor has me feeling pretty hopeless, now re: Cymbalta. Ditto re: the constipation. The nausea I *maybe* could get around using crytallized ginger.
ravenstorm, the only reason I believe I can tolerate Prozac is because I am one for whom 10 mg works better than more. Otherwise, my stomach would never handle it. I may end up just adding Seoquel for sleep to the Prozac, rather than start all over with Cymbalta. If I'd seen more people here getting a good response with Cymbalta in week 1-2, as with Remeron, I'd be more apt to try & weather all the GI side-efeccts that will (let's face it) very likely ensue for me.
New question: for those who are doing well on Cymbalta, did you also happen to do well (mood-wise) on Effexor?
For me, all I got on Effexor was a stimulating response that faded away within weeks to days at each increase, until I finally had to admit that it wasn't doing much, if anything.
Thanx to all who have relpied. I will keep you updated.
blnch
Posted by sunshine211 on November 2, 2004, at 15:41:54
In reply to Re: Cymbalta+seroquel » sunshine211, posted by blnch on November 2, 2004, at 14:31:25
i am glad to hear you are clean, it is definitely a long road i am waiting for my bro to get to the end of all the bad...keep going!
:)
Posted by blnch on November 2, 2004, at 16:02:11
In reply to Re: Cymbalta+seroquel, posted by sunshine211 on November 2, 2004, at 15:41:54
Thank You! My best friend would have had 6 weeks less clean time than me, but he had not, until this time (hopefully), done it for himself. I found that that is the answer - making a committment to yourself, then doing whatever it takes + not using no matter what. Groups, higher power/ god, sponsors were NOT the answer for me, altho I do think going to a 12-step group - for ONLY one reason - to be around others pursuing the same goal is helpful for around 2 yrs, no longer. After that time, it became VERY counter-productive for me. There is alot of hypocricy/ people using other people = no thanx!
blnch
Posted by theo on November 2, 2004, at 16:25:56
In reply to Re: Cymbalta Side-effects/Nausea, etc. ?s, posted by happy lady on November 1, 2004, at 12:52:35
Just curious, are you taking Paxil or Paxil CR?
Posted by ravenstorm on November 2, 2004, at 21:51:03
In reply to Re: Cymbalta Side-effects/Nausea, etc. ?s » happy lady, posted by theo on November 2, 2004, at 16:25:56
I started on 5mg of prozac and the severe stomach distress and Gerd never lessened even at that low dose. I need to get on an SSRI and I can't because of my stomach!!!!!!!!
Posted by banga on November 4, 2004, at 19:02:18
In reply to Re: Cymbalta Side-effects/Nausea, etc. ?s, posted by ravenstorm on November 2, 2004, at 21:51:03
On day 10 at 40mg....so fr OK, no big changes, a little less anxious perhaps....but feel achy and my throat hurts....some mentioned flu-like sxs, does this pass??
Posted by blnch on November 5, 2004, at 11:31:10
In reply to Re: Cymbalta Side-effects/Nausea, etc. ?s, posted by banga on November 4, 2004, at 19:02:18
Hi guys. Saw the new pdoc. He and I chose to look at Cymbalta later on.
Was instead given T3 (Cytomel) to augment Prozac; Seroquel for sleep. Guess what? Both (apparently rare) turned out to bother my stomach - so am ditching both.
Will see him again in 2 weeks. The great thing is that we spent 1/2 of my hour actually talking about (GASP!) the horrible GI side-effects I have. He absolutely believed me. Still in abit of shock over that! Has never happened before - he is pdoc # 6 or 7......
Posted by Gothic54 on November 12, 2004, at 0:22:34
In reply to Cymbalta *is* being studied for chronic pain (nm) » blnch, posted by Racer on October 29, 2004, at 21:05:44
Hi, all! I am a 29 year old woman, newly diagnosed with Fibromyalgia (spelling?)My doctor has had me try nearly every thing for my constant pain and depression; Zoloft, amtriptiline (spell?),skelaxin,trazadone,bextra, flexeril,celexa,mobic,ostio-bioflex,tylonol #3,...the list seems to go on and on. About 2 weeks ago he wanted me to try 60ml of cymbalta. He said it worked as a AD and pain blocker, yet Non-narcotic... For the first time in about a year, I did sit ups today! I did crunches, push ups, cleaned house, and went Christmas shopping with my mother! I felt GREAT! I felt like I was "in my 20's"...and not "70's". I pray that this keeps up. I was so tired of feeling tired, cold, and achy. The last year has been so dificult...now I have stopped taking most of those other meds, and feel great!
FINALLY...A BREAKTHROUGH!!!
Posted by paltiel on November 19, 2004, at 14:55:51
In reply to Re: Cymbalta Side-effects/Nausea, etc. ?s » blnch, posted by CrazyCO on October 30, 2004, at 21:40:08
> I take cymbalta currently 120mg and I have had slight nausea about 30 minutes or so after I take it. But it is more like butterflies than actual nauea and it passes very quickly.
Anything you notice about Cymbalta at 120 mgs? Sufficiently more effective than 90 mgs? Change of side effects (nausea, appetite, insomnia)?
PS - Thanks, CrazyCO
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