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Dr. Bob is Robert Hsiung, MD,
[email protected]Shown: posts 1 to 11 of 11. This is the beginning of the thread.
Posted by BradD on November 2, 2004, at 12:57:33
I'm currently taking both of these meds and am wondering - why did they not get FDA approval?
Especially Reboxetine which is very similar to Strattera?
Just curious...
Posted by jlbl2l on November 2, 2004, at 13:34:49
In reply to Reboxetine/Tianeptine - why no FDA approval?, posted by BradD on November 2, 2004, at 12:57:33
They were never submitted
Posted by BradD on November 2, 2004, at 13:50:36
In reply to Re: Reboxetine/Tianeptine - why no FDA approval?, posted by jlbl2l on November 2, 2004, at 13:34:49
> They were never submitted
I might be wrong on this one - but I think that Reboxetine was submitted and declined (but there was no mention why)... at least that's what I've read somewhere..
jbl -> how are you doing on your Lyrica? Still working wonders on your pro-sociability?
Posted by lostforwards on November 2, 2004, at 14:22:59
In reply to Reboxetine/Tianeptine - why no FDA approval?, posted by BradD on November 2, 2004, at 12:57:33
> I'm currently taking both of these meds and am wondering - why did they not get FDA approval?
> Especially Reboxetine which is very similar to Strattera?
> Just curious...
Something possibly silly...
I have a conspiracy theory that they don't like Tianeptine because, unlike most ADs, it may increase emotional depth and they don't like that.
Posted by jlbl2l on November 2, 2004, at 14:27:45
In reply to Re: Reboxetine/Tianeptine - why no FDA approval? » jlbl2l, posted by BradD on November 2, 2004, at 13:50:36
I dont know, you may be right..
If you scroll up just a few posts above i answered this yedterday, yes it is working great still except for some significant, quick weight gain...
Posted by SLS on November 2, 2004, at 15:12:06
In reply to Re: Reboxetine/Tianeptine - why no FDA approval? » BradD, posted by jlbl2l on November 2, 2004, at 14:27:45
> I dont know, you may be right..
>
> If you scroll up just a few posts above i answered this yedterday, yes it is working great still except for some significant, quick weight gain...
My guess is that there is an early plateauing of weight increase. You probably won't gain anymore. Please continue to post of your progress and side effects. How much has it been - 5 lbs?Thanks.
- Scott
Posted by karaS on November 2, 2004, at 23:11:36
In reply to Re: Reboxetine/Tianeptine - why no FDA approval? » jlbl2l, posted by BradD on November 2, 2004, at 13:50:36
> > They were never submitted
>
> I might be wrong on this one - but I think that Reboxetine was submitted and declined (but there was no mention why)... at least that's what I've read somewhere..
>Brad,
I think they said it wasn't effective enough. Possibly some politics in there as well. How are you doing on reboxetine? Has it helped you a lot? You take tianeptine at the same time? How are you finding that?
Kara
Posted by Pluto on November 3, 2004, at 0:14:47
In reply to Re: Reboxetine/Tianeptine - why no FDA approval? » BradD, posted by karaS on November 2, 2004, at 23:11:36
Reboxetine was submitted to FDA approval, but in clinical trials, neither fluoxetine nor reboxetine found to be significantly superior to placebo. So, Upjohn abandoned the process.
Tianeptine is a French compound, and I think FDA is not interested in French stuffs. Remember the fate of amineptine. It was the best antidepressant ever made in terms of efficacy and tolerability. Perhaps the first antidepressant which improves the quality of sex life. But FDA found some mysterious reasons to force France to abandon the production of it. They say amineptine is affecting the same parts of the brain where amphetamines work. A simple scheduling was sufficient then to restrict the abuse of amineptine. But..........
Posted by KaraS on November 3, 2004, at 12:20:51
In reply to Re: Reboxetine/Tianeptine - why no FDA approval? » karaS, posted by Pluto on November 3, 2004, at 0:14:47
> Reboxetine was submitted to FDA approval, but in clinical trials, neither fluoxetine nor reboxetine found to be significantly superior to placebo. So, Upjohn abandoned the process.
> Tianeptine is a French compound, and I think FDA is not interested in French stuffs. Remember the fate of amineptine. It was the best antidepressant ever made in terms of efficacy and tolerability. Perhaps the first antidepressant which improves the quality of sex life. But FDA found some mysterious reasons to force France to abandon the production of it. They say amineptine is affecting the same parts of the brain where amphetamines work. A simple scheduling was sufficient then to restrict the abuse of amineptine. But..........
I don't understand. If reboxetine tests were similar to fluoxetine, why abandon reboxetine and charge full ahead with fluoxetine?I had read that amineptine could cause spontaneous orgasms. Can't have any of that, now can we?
K
Posted by zeugma on November 4, 2004, at 19:56:18
In reply to Re: Reboxetine/Tianeptine - why no FDA approval? » Pluto, posted by KaraS on November 3, 2004, at 12:20:51
> > Reboxetine was submitted to FDA approval, but in clinical trials, neither fluoxetine nor reboxetine found to be significantly superior to placebo. So, Upjohn abandoned the process.
> > Tianeptine is a French compound, and I think FDA is not interested in French stuffs. Remember the fate of amineptine. It was the best antidepressant ever made in terms of efficacy and tolerability. Perhaps the first antidepressant which improves the quality of sex life. But FDA found some mysterious reasons to force France to abandon the production of it. They say amineptine is affecting the same parts of the brain where amphetamines work. A simple scheduling was sufficient then to restrict the abuse of amineptine. But..........
>
>
> I don't understand. If reboxetine tests were similar to fluoxetine, why abandon reboxetine and charge full ahead with fluoxetine?
>
> I had read that amineptine could cause spontaneous orgasms. Can't have any of that, now can we?
>
No, it would seem somehow un-American in light of our recent elections (there's my oblique political comment for the day).Fluoxetine is a potent suppressor of orgasms. That in itself is reason for FDA approval.
-z
> K
Posted by KaraS on November 4, 2004, at 23:18:45
In reply to Re: Reboxetine/Tianeptine - why no FDA approval? » KaraS, posted by zeugma on November 4, 2004, at 19:56:18
> > > Reboxetine was submitted to FDA approval, but in clinical trials, neither fluoxetine nor reboxetine found to be significantly superior to placebo. So, Upjohn abandoned the process.
> > > Tianeptine is a French compound, and I think FDA is not interested in French stuffs. Remember the fate of amineptine. It was the best antidepressant ever made in terms of efficacy and tolerability. Perhaps the first antidepressant which improves the quality of sex life. But FDA found some mysterious reasons to force France to abandon the production of it. They say amineptine is affecting the same parts of the brain where amphetamines work. A simple scheduling was sufficient then to restrict the abuse of amineptine. But..........
> >
> >
> > I don't understand. If reboxetine tests were similar to fluoxetine, why abandon reboxetine and charge full ahead with fluoxetine?
> >
> > I had read that amineptine could cause spontaneous orgasms. Can't have any of that, now can we?
> >
> No, it would seem somehow un-American in light of our recent elections (there's my oblique political comment for the day).
>
> Fluoxetine is a potent suppressor of orgasms. That in itself is reason for FDA approval.
>
> -z
> > K
>Oh, I see. It's all about preventing orgasms! :-)
-K
This is the end of the thread.
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