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Dr. Bob is Robert Hsiung, MD,
[email protected]Shown: posts 1 to 10 of 10. This is the beginning of the thread.
Posted by linkadge on June 23, 2004, at 11:49:08
I know by most accounts this is a no-no. I am thinking about small doses of celexa 5 mg, combined with perhaps 300-600mg of St, John's wort.
Linkadge
Posted by tampagirl70 on June 23, 2004, at 12:01:08
In reply to st. john's wort + SSRI, posted by linkadge on June 23, 2004, at 11:49:08
what's your reasoning behind those doses?
Posted by linkadge on June 23, 2004, at 12:21:48
In reply to Re: st. john's wort + SSRI, posted by tampagirl70 on June 23, 2004, at 12:01:08
start low to watch for sertonin syndrome.
Linkadge
Posted by crazychickuk on June 23, 2004, at 13:00:56
In reply to Re: st. john's wort + SSRI, posted by linkadge on June 23, 2004, at 12:21:48
wats the difference between sjw and ssri's snris trylics etc... might give it a go myself..
cheers...
currently on 30mg remeron
Posted by Tony C. on June 23, 2004, at 15:27:47
In reply to Re: st. john's wort + SSRI, posted by crazychickuk on June 23, 2004, at 13:00:56
Hi, I think my Doctor told me to NEVER take St. John's wart with SSRI's cause of Seratonin Syndrome, which could be fatal. Because I think St. John's wart acts like an MAOI Inhibitor. So PLEASE be careful
Sincerely- Tony C.
Posted by linkadge on June 23, 2004, at 16:31:11
In reply to Re: WARNING - DANGER ??? st. john's wort + SSRI, posted by Tony C. on June 23, 2004, at 15:27:47
The reason I want to know is, that oftentimes I come off of celexa and onto SJW. I feel very good for the first few days, but as the celexa leaves my system I fade.
Linkadge
Posted by Torque on June 23, 2004, at 22:12:28
In reply to Re: WARNING - DANGER ??? st. john's wort + SSRI, posted by linkadge on June 23, 2004, at 16:31:11
Are you still taking zyprexa?
Posted by linkadge on June 24, 2004, at 9:11:10
In reply to Re: WARNING - DANGER ??? st. john's wort + SSRI » linkadge, posted by Torque on June 23, 2004, at 22:12:28
Yeah,
I guess right now I'm just throwing out ideas.
Linkadge
Posted by Shawn. T. on June 24, 2004, at 18:54:50
In reply to st. john's wort + SSRI, posted by linkadge on June 23, 2004, at 11:49:08
Combining St. John's wort with SSRI's has been said to cause a "mild" serotonin syndrome (see http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11772128 ). Considering that fact and the fact that you're thinking about taking low doses of each, I don't see why any serious problems should be expected. St. John's wort has only very weak MAO inhibitory properties (see http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10761821&dopt=Abstract and http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12775192&dopt=Abstract ). Its influence on serotonin levels probably involves an indirect effect on the serotonin transporter rather than MAO inhibition. As a result, the danger of combining a low dose of St. John's wort with a low dose of an SSRI isn't nearly as great as the danger of combining a strong MAO inhibitor with an SSRI. There is still some risk involved, so use your own best judgment and exercise caution.
Posted by rod on June 25, 2004, at 5:17:36
In reply to Re: st. john's wort + SSRI, posted by Shawn. T. on June 24, 2004, at 18:54:50
I agree with Shawn. I live in a place, where St. Johns wort is a prescription drug and the prescr. info does not state any contraindication. But if you want to make sure, get the ethanol (or methanol?) extract of Johns wort, because it does not have mao inhibitory properties anymore (thats a standardised extraxt which name I dont remenber...)
Roland
This is the end of the thread.
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