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Dr. Bob is Robert Hsiung, MD,
[email protected]Shown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by Camille Dumont on November 17, 2003, at 11:01:08
I've been on Effexor 225mg for maybe a year and I felt fine. Now I can't seem to control my emotions ... feel depressed and suicidal and I cry at the slightest thing...
Can it work and then stop working?
Posted by Jackd on November 17, 2003, at 12:31:36
In reply to Can a med suddenly stop working?, posted by Camille Dumont on November 17, 2003, at 11:01:08
Yep, unfortunately this is known as "poop-out". Do a search on it. It's the worst thing that can happen after a successful trial, IMO, and people have said it can be a sign of an underlying mood disorder (bipolarity).
Posted by T_R_D on November 18, 2003, at 12:12:13
In reply to Can a med suddenly stop working?, posted by Camille Dumont on November 17, 2003, at 11:01:08
> I've been on Effexor 225mg for maybe a year and I felt fine. Now I can't seem to control my emotions ... feel depressed and suicidal and I cry at the slightest thing...
>
> Can it work and then stop working?You're kind of "in the middle" as far as Effexor dose...you could try ramping it up a little bit to see if that helps. I second that emotion re: the bipolarity. That's where I seem to have ended up and am now taking Carbamazepine (Tegretol) and Wellbutrin. Have you had this happen with other meds or is this the first time?
Posted by Camille Dumont on November 18, 2003, at 12:59:02
In reply to Re: Can a med suddenly stop working?, posted by T_R_D on November 18, 2003, at 12:12:13
> > I've been on Effexor 225mg for maybe a year and I felt fine. Now I can't seem to control my emotions ... feel depressed and suicidal and I cry at the slightest thing...
> >
> > Can it work and then stop working?
>
> You're kind of "in the middle" as far as Effexor dose...you could try ramping it up a little bit to see if that helps. I second that emotion re: the bipolarity. That's where I seem to have ended up and am now taking Carbamazepine (Tegretol) and Wellbutrin. Have you had this happen with other meds or is this the first time?This is the first AD I've taken. I've also been on Trazodone for sleep but it made me into a zombie so then they cave me Seroquel and it made me feel even more drowsy and confused so I ditched both.
I remember the pdoc asking about bipolarity ... well at least his questions were easy to spot ... so I guess he concluded that I wasn't depressed or bipolar ... but then again this is the pdoc who sent me home with no meds, no reference and no help to find a therapist ... just telling me to come back if I started to feel suicidal again.
Yippee!
So I don't really trust his judgement anymore.
I guess I'll start by going back to my doctor. Another pdoc (private clinic) prescribed the seroquel to boost it but UGH! I never want to take that stuff again. Hopefully something else might help.
Posted by ditzypixy on November 18, 2003, at 14:45:41
In reply to Can a med suddenly stop working?, posted by Camille Dumont on November 17, 2003, at 11:01:08
i got the same thing after a while on prozac,i was feeling fine,getting all my creativity back,then the same sorta thing happened,id just start crying,or even weirder,for me,snapping at people and feeling aggro. i think what it is is you can get used to it,and need higher doses ,or maybe some modification of it or another drug on top of it,even vitamins like b12 can help your body metabolise certain drugs better.
i found a use for all my old prozac,i emptied out the powder and threaded a needle through a couple,made a necklace out of them!!!
Posted by Jackd on November 19, 2003, at 13:08:39
In reply to Re: Can a med suddenly stop working?, posted by ditzypixy on November 18, 2003, at 14:45:41
> i found a use for all my old prozac,i emptied out the powder and threaded a needle through a couple,made a necklace out of them!!!
Ahahahahahaha! Well looks like whatever you're on gave you your creativity back again.
Posted by cevans on November 19, 2003, at 22:04:05
In reply to Can a med suddenly stop working?, posted by Camille Dumont on November 17, 2003, at 11:01:08
I have a 9yr that breaks through her meds with record breaking speed. She is currently taking 700mgs of Seroquel along with 750mgs of Depakote a day. She has been on soo many variations of drugs I can't count them. They seem to only last through work up and max a month more. Then it is back to the drawing board.
Posted by dandelion on November 20, 2003, at 14:14:04
In reply to Can a med suddenly stop working?, posted by Camille Dumont on November 17, 2003, at 11:01:08
I had a very similar experience; my psy MD gradually increased Effexor Xr from 37.5 to 75, to 112.5, and so on. I have been taking 225mg Qd for over 6 months. When i first began Effexor, I noticed a difference in my mood almost right away. I felt more cheerful, more optimistic...less numb. But suddenly, i seemed to hit a plateau. I downspiraled a bit, and then just leveled out into this zone that fluctuates between extreme sadness and feelings of worthlessness, to feelings close to "normalcy" and contentment. My psy added Wellbutrin after i complained of feelings of rage and hopelessness. This has to yet to make a major difference, except that i have lost the desire to smoke (which is great). I actually posted this same question months ago, when i first began feeling as if Effexor had "pooped out". I don't think anyone ever responded, and i started to believe that i was just going to have to accept that this is how i will feel forever. However, i've also thought, that perhaps this is just not the right med for me anymore. I will be honest and say too, that I've had thoughts of going the "natural" route and trying to go off all the meds to see how i feel. probably not smart. i have a difficult time accepting that i may need to depend on meds for a while, or for the rest of my life, in order to function productively, and feel content with myself and my life.
This is the end of the thread.
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