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Dr. Bob is Robert Hsiung, MD,
[email protected]Shown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by sisyphus on November 3, 2003, at 7:17:12
Dear all,
I heard that St John's wort is acting like MAOI med. And I found that Wellbutrin (bupropion) is contradicting to MAOI. Then is it safe to take them together?
Thanks
Posted by Susan J on November 3, 2003, at 8:53:38
In reply to St John's wort and Wellbutrin, posted by sisyphus on November 3, 2003, at 7:17:12
Hi,
I'm sure others will have better advice than me. I'm on Wellbutrin, and the prescription drug book I have says *not* to take both St. John's Wort and WB. Why? I have no clue....and have no personal experience with mixing the two....
Posted by sisyphus on November 3, 2003, at 22:08:10
In reply to Re: St John's wort and Wellbutrin ?sisyphus, posted by Susan J on November 3, 2003, at 8:53:38
Thanks a lot.
In Hong Kong, I can only buy Zyban here. The note only says that bupropion cannot be taken with MAOI. I think that your drug book is referring to it. However, I found that whether St John's is a kinda MAOI is still controversial. Many believe that it is not.
Thanks.
> Hi,
>
> I'm sure others will have better advice than me. I'm on Wellbutrin, and the prescription drug book I have says *not* to take both St. John's Wort and WB. Why? I have no clue....and have no personal experience with mixing the two....
Posted by linkadge on November 4, 2003, at 8:46:50
In reply to Re: St John's wort and Wellbutrin, posted by sisyphus on November 3, 2003, at 22:08:10
I'd say this is a no-no. I serotonin syndrome for SJW alone. Dopaminergic meds can (although not directly serotogenic) can actual enhance the possiblility of geting serotonin syndrome.
Ie the same reason you can get SS from Wellbutrin and an MAOI.
Take Care
Linkadge
Posted by Larry Hoover on November 4, 2003, at 9:21:18
In reply to St John's wort and Wellbutrin, posted by sisyphus on November 3, 2003, at 7:17:12
> Dear all,
>
> I heard that St John's wort is acting like MAOI med.At *almost* undetectable levels. The original report of the MAO activity failed to disclose that the doses used were 300 times the therapeutic dose.
> And I found that Wellbutrin (bupropion) is contradicting to MAOI. Then is it safe to take them together?
>
> ThanksIt would be no different than using Wellbutrin with an SSRI. Caution is warranted. Dose should be very carefully and gradually increased.
Lar
This is the end of the thread.
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