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Dr. Bob is Robert Hsiung, MD,
[email protected]Shown: posts 1 to 11 of 11. This is the beginning of the thread.
Posted by Questionmark on June 9, 2003, at 1:19:20
How does Nardil affect your word retrieval/recall?
Posted by Merci on June 9, 2003, at 10:43:33
In reply to Nardil, posted by Questionmark on June 9, 2003, at 1:19:20
Interesting...
My word retrieval/recall has definitely taken a turn for the worse since I started on Nardil - I guess I've kind of assumed it was due to the depression but perhaps it's chemically induced? Hmm, one more thing to think about.
Posted by Carlos on June 9, 2003, at 13:05:07
In reply to Re: Nardil, posted by Merci on June 9, 2003, at 10:43:33
It was bad at first (first week or two) It's fine now.
Posted by indivmed on June 9, 2003, at 15:17:11
In reply to Re: Nardil, posted by Carlos on June 9, 2003, at 13:05:07
I am curious as to whether or not that is a common thread with the MAOIs...I started Parnate a week ago and my word recall is really bad and for some reason, I have problems making the simplest decision (today, whether or not to get chicken nuggets or a chicken sandwich--at least a 15 minute call).
Besides that, I'm actually not depressed now. The Parnate seems to work.
By the way, has anyone taken Wellbutrin with an MAOI...I know it's been done for some in a very careful manner--as with some other stimulants, TCAs, etc...
Posted by ace on June 9, 2003, at 20:29:43
In reply to Nardil, posted by Questionmark on June 9, 2003, at 1:19:20
Posted by Questionmark on June 10, 2003, at 0:26:03
In reply to Re: Nardil/Parnate, posted by indivmed on June 9, 2003, at 15:17:11
Thank you for the responses everyone.
> I am curious as to whether or not that is a common thread with the MAOIs...I started Parnate a week ago and my word recall is really bad and for some reason, I have problems making the simplest decision (today, whether or not to get chicken nuggets or a chicken sandwich--at least a 15 minute call).
Oh i freaking HATE that!! (the indecisive crap). That might actually be from an aggravation of obsessive-compulsive shi* if you have some OC problems anyway though, BUT...
if not, i think that, as well as your poor word recall, will improve. Parnate is supposed to have procognitive effects (i'm pretty sure) and for the most part has definitely had them w/ me in the month that i've been on it-- including word retrieval (unless it just increases my confidence level enough to make me stupid enough to THINK that my cognition and word-usage is better!! -- WOULDN'T be surpRISed!!).
But yeah, i was afraid if i switched to Nardil that i would become a bumbling baffoon again-- but from what you all said it looks like that effect goes away shortly. That's good news. Thanks.
Posted by cosis on June 10, 2003, at 8:59:23
In reply to Re: Nardil, posted by Merci on June 9, 2003, at 10:43:33
> Interesting...
>
> My word retrieval/recall has definitely taken a turn for the worse since I started on Nardil - I guess I've kind of assumed it was due to the depression but perhaps it's chemically induced? Hmm, one more thing to think about..
Posted by temoigneur on June 20, 2003, at 0:14:28
In reply to No effect on it.... (nm) » Questionmark, posted by ace on June 9, 2003, at 20:29:43
Hey everyone, ace, how are you? I'm on about my third or fourth week of Nardil at 60 mg, it's definately struck a blow to my anxiety, but I'm also on zyprexa, 10mg and 7mg clonazepam, and I'm usually tired, but worse yet, I'm fairly depressed, sometimes for hourss on end. I don't know if this could be due to the dopamine blocking effects of zyprexa, any thoughts - thanks.
Posted by Questionmark on June 20, 2003, at 0:40:08
In reply to Nardil and Depression » ace, posted by temoigneur on June 20, 2003, at 0:14:28
> Hey everyone, ace, how are you? I'm on about my third or fourth week of Nardil at 60 mg, it's definately struck a blow to my anxiety, but I'm also on zyprexa, 10mg and 7mg clonazepam, and I'm usually tired, but worse yet, I'm fairly depressed, sometimes for hourss on end. I don't know if this could be due to the dopamine blocking effects of zyprexa, any thoughts - thanks.
Well you're on three sedating drugs at once, so this isn't at all surprising. i would personally think of doing one of two things, or both: decrease the zyprexa to 5 or 2.5 mg or just discontinue it, and/or, decrease your Klonopin dose. This depends on how long you've been on 7mg Klonopin and if you really think you need that high a dose. But 7mg seems pretty high (unless u have epilepsy or something), so i would also definitely think about lowering that-- especially since you're going to be getting added GABAergic-type effects from the Nardil (in addition to that from the Klonopin-- yes its a benzo. agonist but benzos stimulate GABA release i'm pretty sure).
Good luck.
Posted by ace on June 22, 2003, at 22:18:00
In reply to Nardil and Depression » ace, posted by temoigneur on June 20, 2003, at 0:14:28
> Hey everyone, ace, how are you? I'm on about my third or fourth week of Nardil at 60 mg, it's definately struck a blow to my anxiety, but I'm also on zyprexa, 10mg and 7mg clonazepam, and I'm usually tired, but worse yet, I'm fairly depressed, sometimes for hourss on end. I don't know if this could be due to the dopamine blocking effects of zyprexa, any thoughts - thanks.
Good to hear from you mate!,
Zyprexa in my opinion, would augment The AD effect of Nardil at the right dose. I agree with Questionmark - I think your doses of these two other agents are too high- for example try 5mg Zypexa with 2mg Klonopin. You naturally are feeling very sedate and that might be negating the activation and motivation Nardil can give you.
Also, you might not be metabolzing Nardil right- in other words you might need a 90mg dose.
Also, you might just need a little more time on it.
Whatever the case the prospect looks good.
Let me know how you ar going ASAP!
Ace.
Posted by temoigneur on June 23, 2003, at 0:21:19
In reply to Re: Nardil and Depression » temoigneur, posted by ace on June 22, 2003, at 22:18:00
> > Hey everyone, ace, how are you? I'm on about my third or fourth week of Nardil at 60 mg, it's definately struck a blow to my anxiety, but I'm also on zyprexa, 10mg and 7mg clonazepam, and I'm usually tired, but worse yet, I'm fairly depressed, sometimes for hourss on end. I don't know if this could be due to the dopamine blocking effects of zyprexa, any thoughts - thanks.
>
> Good to hear from you mate!,
>
> Zyprexa in my opinion, would augment The AD effect of Nardil at the right dose. I agree with Questionmark - I think your doses of these two other agents are too high- for example try 5mg Zypexa with 2mg Klonopin. You naturally are feeling very sedate and that might be negating the activation and motivation Nardil can give you.
>
> Also, you might not be metabolzing Nardil right- in other words you might need a 90mg dose.
>
Hey Ace, thanks for the advice, how u doing? I have to admit that I'm still often quite depressed on the nardil, still 60mg, and I worry that the anxiety will come back if I lower the dose of zyprexa or clonazepam, I was hoping the nardil would kick in powerfully I've been on it for about a month. I don't see my pdoc for another week and a half - I think I'm going to try raising the dose to 90, not that 30 more milligrams of the effect I'm already getting would be satisfactory at all, but perhaps the nardil is on the verge of kicking in. I'm impetuous, I'll hope what's going on is a combination of what you say, that it needs more time and I need a higher dosage. I'll keep you abreast.
> Also, you might just need a little more time on it.
>
> Whatever the case the prospect looks good.
Thanks ->
>
Let me know how you ar going ASAP!
>
> Ace.Take care, You're the best,
Ben
This is the end of the thread.
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