![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
[email protected]Shown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by Franz on November 3, 2002, at 10:09:40
I am curious why I donīt read much about Buspirone here and on other boards. Also, I never met a person who was using it, but yes I found a psychiatrist that used it for long term anxiety.
In theory it should work by boosting the serotonin S1 receptor, and so control the release if GABA.
Is it a case when the drug does not make any strong noticeable effect is taken as not working by patients?.
Looks like a drug I should consider and compare to clonazepam.
Thanks
Posted by lrw on November 3, 2002, at 11:12:19
In reply to Buspar/buspirone, posted by Franz on November 3, 2002, at 10:09:40
I took Buspar for a few months and it worked a little. I took 10 mg in the morning, 10 mg in afternoon and 10 at night. I don't know if it was just me but all 3 times it just about knocked me out. I could hardly hold my head up from being so tired. I ended up going on 5mg, 5mg and 10 mg at night but that didn't do much for my anxiety. I am now taking Zoloft in the morning and 10 of Buspar at night. The Buspar helps with sleep and sexual disfunction that is caused by the Zoloft.
Posted by cab on November 3, 2002, at 11:57:02
In reply to Buspar/buspirone, posted by Franz on November 3, 2002, at 10:09:40
I don't think my experience is typical, but I tried it for a couple of weeks (I was already taking effexor and lithium) and my anxiety got much, much worse. As soon as I stopped the anxiety improved.
> I am curious why I donīt read much about Buspirone here and on other boards. Also, I never met a person who was using it, but yes I found a psychiatrist that used it for long term anxiety.
>
> In theory it should work by boosting the serotonin S1 receptor, and so control the release if GABA.
>
> Is it a case when the drug does not make any strong noticeable effect is taken as not working by patients?.
>
> Looks like a drug I should consider and compare to clonazepam.
>
> Thanks
>
Posted by utopizen on November 3, 2002, at 13:56:03
In reply to Re: Buspar/buspirone, posted by cab on November 3, 2002, at 11:57:02
> I don't think my experience is typical, but I tried it for a couple of weeks (I was already taking effexor and lithium) and my anxiety got much, much worse. As soon as I stopped the anxiety improved.
>Me too. I went from just SP to total GAD while on it. Stopped it, andit got back to normal anxiety for me.
Posted by Ed O`Flaherty on November 3, 2002, at 15:00:36
In reply to Buspar/buspirone, posted by Franz on November 3, 2002, at 10:09:40
I have seen a lot of people try it but very few stayed on it for long.It takes weeks to work,that is if it works at all.It is though among the hundred most prescribed drugs in the U.S.
Posted by Ritch on November 3, 2002, at 16:10:00
In reply to Buspar/buspirone, posted by Franz on November 3, 2002, at 10:09:40
> I am curious why I donīt read much about Buspirone here and on other boards. Also, I never met a person who was using it, but yes I found a psychiatrist that used it for long term anxiety.
>
> In theory it should work by boosting the serotonin S1 receptor, and so control the release if GABA.
>
> Is it a case when the drug does not make any strong noticeable effect is taken as not working by patients?.
>
> Looks like a drug I should consider and compare to clonazepam.
>
> Thanks
>
Buspar is a strange drug. I took it for a few weeks a couple of times previously. I found it didn't do diddly-squat by itself. However, I combined it with desipramine one time and it made my anxiety much worse. I combined it with Celexa one time and I found a powerful anti-anxiety combo. there. The only problem was that all of my anxiety was replaced with hostility and aggression. I had to be very careful to make sure the Celexa dosage had the upper hand with the Buspar or I would get rages while on it.
Posted by linkadge on November 3, 2002, at 18:03:43
In reply to Re: Buspar/buspirone ŧ Franz, posted by Ritch on November 3, 2002, at 16:10:00
I know what you mean, I took
Celexa with Remeron a few times,
very powerful antianxiety, very good
for sleep but just irritable as
all get out.Linkadge
Posted by jflange on November 7, 2002, at 16:01:01
In reply to Re: Buspar/buspirone ŧ Franz, posted by Ritch on November 3, 2002, at 16:10:00
I agree with Ritch that Buspar does not work well as a monotherapy but ever since I used it in combination with Zoloft, it has been a >much< more effective treatment for anxiety than ssris alone or ssris with a benzo.
While the exact mechanism of Buspar is unknown, the theory is that it both agitates and inhibits the reuptake of serotonin. Taken with an ssri, Buspar can really boost the good effects of an ssri without all the unpleasant side effects of simply increasing the ssri dose. I think, too, it must modulate these S1 receptors in some way that adresses anxiety where ssris do not.
Franz, I think you do not hear much about this drug because it is a sort of disappointing precursor to the ssris, and has never had the marketable quality of being a magic bullet. But hey, it does have one thing over clonazepam: no withdrawals!
jflange
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
[email protected]
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.