Psycho-Babble Medication Thread 103651

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Which is the less sedative, most activating SSRI?

Posted by dazednconfused on April 20, 2002, at 13:48:23

Hi, please would you help me to know which is the less sedative, most activating SSRI?
I got a lot of sedation, drowsiness on SSRI like Effexor and Paxil.
Is there any activating or less sedative on the market?
Thanks very much for your help!

 

Re: Which is the less sedative, most activating SSRI?

Posted by paulb on April 20, 2002, at 14:40:01

In reply to Which is the less sedative, most activating SSRI?, posted by dazednconfused on April 20, 2002, at 13:48:23

according to most clinicians the most to least agitating are:
Fluoxetine
Sertraline
Citalopram
Fluvoxamine
Paroxetine

ive been on Paroxetine, Fluvoxamine and Sertraline and would agree with this. however I would think Mirtazapine and Nefazadone would be the most sedative antidepressants. theres no reason also why you couldnt take Fluoxetine or Sertraline and if you found it too stimulating augment an atypical antipsychotic.
paulb

 

Re: Which is the less sedative, most activating SSRI?

Posted by turalizz on April 20, 2002, at 15:55:00

In reply to Which is the less sedative, most activating SSRI?, posted by dazednconfused on April 20, 2002, at 13:48:23

> Hi, please would you help me to know which is the less sedative, most activating SSRI?
> I got a lot of sedation, drowsiness on SSRI like Effexor and Paxil.
> Is there any activating or less sedative on the market?
> Thanks very much for your help!

Why do you want to try another SSRI, but not another antidepressant?

I had some narcolepsi-like attacks in the past, and slept over 10 hours every day.

The antidepressant that saved my life was mianserin, an older, extremely sedative antidepressant. The AD's having sedative effecs doesn't mean that, that effect will last throughout the day, but it possibly might. A newer AD, Remeron (starting from 30 mg/day, as it might be more sedating in small doses) might be a choice I think.

From my perspective, the AD's I found to be sitimulating are: Tolvon(mianserin), Remeron, Reboxetine, Aurorix(moclobemide; and NONE of the SSRI's, but YMMV as always.

cem

 

Re: Which is the less sedative, most activating SSRI?

Posted by rainbowlight on April 21, 2002, at 1:33:57

In reply to Which is the less sedative, most activating SSRI?, posted by dazednconfused on April 20, 2002, at 13:48:23

For me, and I have tried most of them, the most activating was Celexa. My pdoc has also told me that Zoloft is activating, I started it two weeks ago, a tiny bit of sedation, but nothing like the sedation from Luvox or Paxil. I also take Remeron. It is suppossed to be highly sedating, but it doesn't sedate me at all (but then I never get the NORMAL side effects, lol!)

 

Re: Which is the less sedative, most activating SSRI?

Posted by tex1 on April 22, 2002, at 8:11:35

In reply to Which is the less sedative, most activating SSRI?, posted by dazednconfused on April 20, 2002, at 13:48:23

> Hi, please would you help me to know which is the less sedative, most activating SSRI?
> I got a lot of sedation, drowsiness on SSRI like Effexor and Paxil.
> Is there any activating or less sedative on the market?
> Thanks very much for your help!

Everyone has his own balance, so it's difficult to advise you in this case. The only thing is just trying. According to most part of the studies the less sedating are fluoxetine and mirtazapine.
Best luck.

Tex

 

Re: Which is the less sedative, most activating SSRI?

Posted by beetle on April 23, 2002, at 21:11:29

In reply to Which is the less sedative, most activating SSRI?, posted by dazednconfused on April 20, 2002, at 13:48:23

Activating: Celexa, Paxil, Effexor
Sedating: Remeron


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